Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
Source abstract
Abstract
A system for measuring small oil droplets in an oil-in-water (O/W) emulsion was developed using multiphoton ionization time-of-flight mass spectrometry. In the present study, a capillary column with an inner diameter of 15 µm was used for sample introduction. Moreover, a compact microscopic system was constructed for observing an emulsion flowing through a capillary column. As a result, the length for sample introduction was shortened, which is preferable for the direct evaluation of an emulsion. Using this system, the minimum diameter of a detectable toluene droplet in an O/W emulsion was decreased to 1.7 µm. The present system could be used to evaluate the local microenvironment and stability of an emulsion.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Mass Spectrometry Techniques and Applications · Innovative Microfluidic and Catalytic Techniques Innovation · Analytical Chemistry and Chromatography
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan
Funding
JGC-S Scholarship Foundation
References (32)
Show source-provided references
1. Tadros, T.F. (2009). Emulsion Science and Technology, Wiley-VCH. Chapter 1.10.1002/9783527626564.ch1 ↗
2. Temperature-induced coalescence of droplets manipulated by optical trapping in an oil-in-water emulsion10.2116/analsci.33.709 ↗
3. Fusion of microlitre water-in-oil droplets for simple, fast and green chemical assays10.1039/C5AN00847F ↗
4. Monitoring interfacial lipid oxidation in oil-in-water emulsions using spatially resolved optical techniques10.1021/acs.analchem.7b01228 ↗
5. Luminol chemiluminescence profile of o/w emulsions during thermal oxidation10.2116/analsci.33.249 ↗
6. Determination of the electrostatic potential of oil-in-water emulsion droplets by combined use of two membrane potential-sensitive dyes10.2116/analsci.33.813 ↗
7. Monodisperse double emulsions generated from a microcapillary device10.1126/science.1109164 ↗
8. A simple microfluidic method for one-step encapsulation of reagents with varying concentrations in double emulsion drops for nanoliter-scale reactions and analyses10.1039/C7AY00544J ↗
9. Fluorescence correlation spectroscopy: An efficient tool for measuring size, size-distribution and polydispersity of microemulsion droplets in solution10.1021/ac2012637 ↗
10. Role of hydrocolloids in the creaming of oil in water emulsions10.1021/jf020664n ↗
11. Highly stable concentrated nanoemulsions by the phase inversion composition method at elevated temperature10.1021/la302995a ↗
12. Sensitive, high throughput detection of proteins in individual, surfactant-stabilized picoliter droplets using nanoelectrospray ionization mass spectrometry10.1021/ac400453t ↗
13. Laser ionization/time-of-flight mass spectrometry for the direct analysis of emulsions10.1039/C4AY00633J ↗
14. Time-of-flight mass spectrometry: Introduction to the basics10.1002/mas.21520 ↗
15. Mass spectrometry of aromatic molecules with resonance-enhanced multiphoton ionization10.1021/ac00241a014 ↗
16. Resonant two-photon ionization and mass-analyzed threshold ionization spectroscopy of the selected rotamers of m-methoxyaniline and o-methoxyaniline10.1016/j.jms.2007.05.001 ↗
17. In situ, fast-response, molecular-selective methods for measuring emission factors of volatile organic compounds (VOCs) into the atmosphere10.1246/cl.2009.74 ↗
18. Ultraviolet femtosecond laser ionization mass spectrometry10.1002/tcr.20136 ↗
19. Near-real-time combustion monitoring for PCDD/PCDF indicators by GC-REMPI-TOFMS10.1021/es2027339 ↗
20. Determination of nerve agent metabolites by ultraviolet femtosecond laser ionization mass spectrometry10.1021/acs.analchem.7b00386 ↗
21. Rapid evaluation of the bioremediation of fuel oil in soil by gas chromatography–laser ionization time-of-flight mass spectrometry10.1080/00032719.2017.1319378 ↗
22. Analytical jet spectroscopy of tyrosine and its analogs using a pulsed laser desorption volatilization method10.1366/0003702884427825 ↗
23. Factors affecting quantitative analysis in laser desorption/laser ionization mass spectrometry10.1021/ac0354140 ↗
24. Laser mass spectrometric analysis of polycyclic aromatic hydrocarbons with wide wavelength range laser multiphoton ionization spectroscopy10.1021/ac971264f ↗
25. Pyrolysis-gas chromatography/multiphoton ionization/time-of-flight mass spectrometry for the rapid and selective analysis of polycyclic aromatic hydrocarbons in aerosol particulate matter10.2116/analsci.30.891 ↗
26. Detection limits of organic compounds achievable with intense, short-pulse lasers10.1039/C5AN00529A ↗
27. Aerosol mass spectrometer for simultaneous detection of polyaromatic hydrocarbons and inorganic components from individual particles10.1021/acs.analchem.7b01207 ↗
28. Laser ionization time-of-flight mass spectrometry for the evaluation of a local microenvironment in an emulsion10.1039/C5AY01490E ↗
29. Online monitoring of a styrene monomer and a dimer in an emulsion via laser ionization time-of-flight mass spectrometry10.2116/analsci.33.731 ↗
30. Evaluating the aging of multiple emulsions using resonance-enhanced multiphoton ionization time-of-flight mass spectrometry10.2116/analsci.32.789 ↗
31. A quantitative analysis of an oil component in an emulsion by multiphoton ionization mass spectrometry10.2116/analsci.33.1067 ↗
32. Time-profile measurement of an emulsion using multiphoton ionization time-of-flight mass spectrometry in combination with a microscope10.2116/analsci.32.1059 ↗