Does Platelet-Rich Fibrin Decrease Dimensional Changes and Improve Postoperative Comfort in Post-Extraction Sockets? An Overview of Systematic Reviews
Source abstract
Abstract
This overview aimed to evaluate the methods, quality, and outcomes of systematic reviews (SRs) conducted to investigate the effects of platelet-rich fibrin (PRF) in dental sockets on promoting bone regeneration and soft tissue healing and diminishing the incidence of pain, swelling, trismus, and alveolar osteitis after tooth extraction. An electronic search without date or language restriction was done in PubMed/MEDLINE, Cochrane, and Web of Science until March 2020. Eligibility criteria included SRs that assessed the effect of PRF for human alveolar socket preservation. The quality assessment of the included studies was performed using AMSTAR 2 guidelines. The protocol of this overview was recorded in PROSPERO under the number CRD42018089617. The search and selection process yielded 13 studies published between 2011 and 2018. The analysis of the studies showed inconclusive data for the effect of the PRF and the dimensional changes. There is no definitive evidence for the impact of using PRF alone on bone regeneration in post-extraction sockets. The use of PRF improves soft tissue healing and reduces pain, bleeding, and osteitis in post-extraction sockets.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Periodontal Regeneration and Treatments · Dental Radiography and Imaging · Dental Implant Techniques and Outcomes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Research in Periodontics, School of Dentistry, Universidade Veiga de Almeida, Rio de Janeiro 20271-020, Brazil
Postgraduate Program in Dentistry School, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24020-140, Brazil
Department of Oral Surgery, School of Dentistry, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24220-900, Brazil
Private Practice, 86170 Isernia, Italy
Private Practice, 24121 Bergamo, Italy
Department of Orthodontics, School of Dentistry, Universidade Federal Fluminense, Niterói, Rio de Janeiro 24020-140, Brazil
Funding
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
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