Mechanically Strong CaSiO3 Scaffolds Incorporating B2O3-ZnO Liquid Phase
Source abstract
Abstract
Calcium silicate (CaSiO3) scaffolds were reinforced by introducing liquid phase. The liquid phase was made of B2O3 and ZnO. The fracture toughness and compressive strength increased by 48% and 141%, respectively, compared with those of the scaffolds without the liquid phase. This was attributed to the enhanced densification, the elongated grains pull-out and the cracks bridging. In addition, because of its increasing mechanical properties, the fracture model of the cleavage fracture was more beneficial than the intergranular fracture. The mechanical properties of the scaffolds with the liquid phase could be steadily maintained and then they decreased slowly when immersed in simulated body fluid (SBF). Meanwhile, the hydroxyapatite (HAp) generated on their surfaces. In addition, the scaffolds possessed favorable biocompatibility and could promote cell proliferation. These results demonstrated that the scaffolds with B2O3-ZnO liquid phase are a promising substitute for bone repair applications.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Calcium Carbonate Crystallization and Inhibition · Dental Implant Techniques and Outcomes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China
State Key Laboratory for Powder Metallurgy, Central South University, Changsha 410083, China
State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi’an 710072, China
Key Laboratory of Carcinogenesis of the Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha 410083, China
College of Chemistry, Xiangtan University, Xiangtan 411105, China
Health Management Center, Xiangya Hospital, Central South University, Changsha 410008, China
Human Reproduction Center, Shenzhen Hospital of Hongkong University, Shenzhen 518053, China
Funding
The Natural Science Foundation of China · Overseas, Hong Kong & Macao Scholars Collaborated Researching Fund of National Natural Science Foundation of China · Hunan Provincial Natural Science Foundation of China
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