A Double Closed-Loop Process for Nanoparticle Synthesis via Aerosol Mixing and Venturi Jet Scrubbing
Source abstract
Abstract
Inorganic nanoparticles (NPs) have been synthesised via mixing and coalescence of droplets containing precursors and entrained by gaseous streams. The droplets have been generated by ultrasonic aerosolisation of two different liquid phases, each containing the respective reagent. The as-produced NPs are trapped by mixing with a liquid phase in a Venturi nozzle, acting simultaneously as a collector and concentrator of the solid nanosized phase produced. Commercial electrically powered ultrasonic aerosolising devices have been adapted to atomise salt solutions characterised by high electrical conductivity. This process allowed the synthesis of calcium carbonate NPs with an average diameter in the range of (34–52) nm, according to the concentration of precursors in the aerosolised phases. This closed-loop method of synthesis, where neither capping agents were used nor demanding operating conditions were adopted, can represent a safe and viable eco-friendly technique for NP production free of undesirable compounds, as required for pharmaceutical preparations and theranostic uses.
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Research context
OpenAlex topics: Coagulation and Flocculation Studies · Electrohydrodynamics and Fluid Dynamics · Minerals Flotation and Separation Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
DICCA, Department of Civil, Chemical and Environmental Engineering, Polytechnic School, University of Genova, Via Opera Pia 15, 16145 Genova, Italy
DIFI, Department of Physics, University of Genova, Via Dodecaneso 33, 16146 Genova, Italy
DCCI, Department of Chemistry and Industrial Chemistry, University of Genova, Via Dodecaneso 31, 16146 Genova, Italy
References (53)
Show source-provided references
1. Energy transition technology comes with new process safety challenges and risks—What does it mean?10.1002/prs.12593 ↗
2. Nano-PCM materials: Bridging the gap in energy storage under fluctuating environmental conditions10.1016/j.psep.2024.06.079 ↗
3. Magnetic phase separation in the EuPdSn2 ground state10.1039/D3TC00764B ↗
4. Synthesis, crystal structure and physical properties of Yb2Pd3Ge510.1016/j.jallcom.2018.12.306 ↗
5. Nanotechnology in machining processes: Recent advances10.1016/j.procir.2019.02.002 ↗
6. Nanotechnology revolutionizing heat transfer: A review of nanofluid research and applications
7. Ali, N., Bilal, M., Khan, A., Nguyen, T.A., and Gupta, R.K. (2023). Organic and inorganic nanoparticles. Smart Polymer Nanocomposites, Elsevier.
8. Organic and inorganic nanomaterial coatings for the prevention of microbial growth and infections on biotic and abiotic surfaces10.1016/j.surfcoat.2021.127739 ↗
9. Jacob, J., Cacciotti, I., and Thomas, S. (2024). Polymer–silver composites for food packaging. Nanostructured Materials for Food Packaging Applications, Elsevier.
10. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery10.1021/nn800072t ↗
11. Inorganic nanoparticles: Toxic effects, mechanisms of cytotoxicity and phytochemical interactions
12. Shape control of inorganic nanoparticles from solution10.1039/C5NR07681A ↗
13. Current trends: Zinc oxide nanoparticles preparation via chemical and green method for the photocatalytic degradation of various organic dyes10.1016/j.hybadv.2023.100128 ↗
14. Making photonic crystals via evaporation of nanoparticle-laden droplets on superhydrophobic microstructures10.1021/acs.langmuir.0c00193 ↗
15. A comprehensive review on various techniques used for synthesizing nanoparticles10.1016/j.jmrt.2023.09.291 ↗
16. Biosynthesis of silver nanoparticles by using Fusarium oxysporum and their therapeutic applications
17. A sustainable, top-down mechanosynthesis of carbohydrate-functionalized silver nanoparticles10.1039/D1RE00391G ↗
18. Green synthesis of silver nanoparticles by low-energy wet bead milling of metal spheres10.3390/ma13010063 ↗
19. An improved model of an ASR pyrolysis reactor for energy recovery10.1016/j.energy.2005.10.024 ↗
20. A comparative analysis of chemical vs. green synthesis of nanoparticles and their various applications
21. Dielectric function of gold nanoparticles synthesized using Camellia sinensis extract10.1007/s11468-022-01776-8 ↗
22. Microwave-assisted synthesis of silver nanoparticles using extract of unbaked cilembu sweet potato10.1088/1742-6596/2866/1/012002 ↗
23. Controlled synthesis of alumina in a spray flame aerosol reactor10.1111/jace.18128 ↗
24. Novel Venturi injector reactor design with multiple inlets in ammonia–nitrogen wastewater10.1016/j.seppur.2025.132062 ↗
25. Nano-CaCO3 synthesis by jet-reactor from calcium carbide slag10.1088/2053-1591/abc654 ↗
26. Loop Venturi reactor-A feasible alternative to stirred tank reactors?10.1021/ie970313b ↗
27. Novel Venturi injector reactor design and application in ammonia nitrogen wastewater treatment10.1016/j.jwpe.2024.106352 ↗
28. A venturi reactor with an excellent mass transfer performance for carbon dioxide capture10.1016/j.jenvman.2024.121144 ↗
29. Mass transfer enhancement for simultaneous desulfurization and denitrification by a venturi reactor10.1016/j.jece.2024.113216 ↗
30. Synthesis and characterization of calcite nano-particle derived from cockle shell for clinical application10.11113/aej.v10.15538 ↗
31. Fabrication and characterization of calcium carbonate nanoparticles for delivery of doxorubicin in breast cancer cells10.1016/j.jddst.2025.106979 ↗
32. Folic acid receptor conjugated mesoporous CaCO3 nanoformulation for the therapeutic potential against lung carcinoma10.1016/j.jddst.2024.105392 ↗
33. Smart responsive-calcium carbonate nanoparticles for dual-model cancer imaging and treatment10.1016/j.ultras.2020.106198 ↗
34. NIR-responsive CaCO3@ BMP-2/PDA nanocomposite for multifunctional therapy in periodontitis10.1016/j.colsurfa.2025.136520 ↗
35. Preparing calcium carbonate nanoparticles from biomass waste and its application as fire-retardant agent
36. LIBS and pXRF validation for the removal of Pb by bio-CaCO3 nanoparticles from contaminated water10.1007/s42452-022-05014-y ↗
37. Copper biosorption onto Rhizopus oligosporus: PH-edge tests and related kinetic and equilibrium modeling10.1021/ie020829h ↗
38. Adsorption of carbonate and bicarbonate salts at the air–brine interface10.1016/j.minpro.2006.07.016 ↗
39. Molecular features of the air/carbonate solution interface10.1016/j.jcis.2007.09.097 ↗
40. New insight into the effect of mass transfer on the synthesis of silver and gold nanoparticles10.1039/C8CE01014E ↗
41. Rapid in-droplet tri-fluid micromixing and concentration gradient generation for nanoparticle synthesis10.1016/j.colsurfa.2024.135983 ↗
42. Kašpar, O., Koyuncu, A.H., Pittermannová, A., Ulbrich, P., and Tokárová, V. (2019). Governing factors for preparation of silver nanoparticles using droplet-based microfluidic device. Biomed. Microdevices, 21.10.1007/s10544-019-0435-4 ↗
43. Controlled and tunable polymer particles’ production using a single microfluidic device10.1007/s13204-018-0790-0 ↗
44. Synthesis of MoS2 nanoparticles grown on crumpled 3D graphene microballs using a microfluidic droplet generator10.1007/s42823-021-00253-2 ↗
45. Saqib, M., Tufan, Y., Cemre Orsel, Z., Ercan, B., and Erdem, E.Y. (2024). Biocompatible Janus microparticle synthesis in a microfluidic device. Biomed. Microdevices, 26.10.1007/s10544-024-00711-4 ↗
46. Preparation of TiO2 nanoparticle aggregates and capsules by the ‘Two-Emulsion Method’10.3390/colloids4040057 ↗
47. Aerosol processing: A wind of innovation in the field of advanced heterogeneous catalysts10.1039/C7CS00697G ↗
48. A multi-nebulizer-based aerosol-assisted system for the synthesis of magnetic iron mixed metal oxides nanoparticles (MFe2O4, M = Fe2+, Ni2+, Mn2+, Co2+, Zn2+)10.1007/s11696-023-02987-x ↗
49. Synthesis of monodisperse gold nanoparticles via electrospray-assisted chemical reduction method in cyclohexane10.1016/j.colsurfa.2015.04.040 ↗
50. Aerosol-assisted synthesis of mesoporous Cu/ZnO–ZrO2 catalyst with highly selective photothermal CO2 reduction to methanol10.1039/D3DT00222E ↗
51. Ultrasound-assisted synthesis of titania nanoparticles, characterization of their thin films, and activity in photooxidation of -β-naphthol10.1007/s11664-015-3996-x ↗
52. Trends and opportunities for greener and more efficient microbially induced calcite precipitation pathways: A strategic review10.1680/jgere.24.00039 ↗
53. Life cycle impact of titanium dioxide nanoparticle synthesis through physical, chemical, and biological routes10.1021/acs.est.8b06800 ↗