Numerical Simulation and Analysis of Heart–Aorta Fluid–Structure Interaction Based on S-ALE Method

The aim of this study is to understand the hemodynamic responses in the heart–aorta system under physiological states and use this understanding to enhance the hemodynamic response analysis of cardiovascular fluid–structure interaction (FSI) models. This article developed a heart–aorta FSI model by constructing a structured fluid domain using the S-ALE method. The model realized a cardiac blood pumping pattern by applying a time-varying displacement load to the left ventricle (LV). The simulation reliability of the model was effectively verified by comparing the hemodynamic responses to the literature data. The FSI analysis in different physiological states showed that the altered ejection volume due to changes in LV systole displacement was a key factor influencing the hemodynamic response. As LV systole displacement increased, blood velocity, flow rate, and wall shear stress (WSS) showed a significant linear increase. The effect of changes in blood viscosity on the WSS demonstrated a significant linear correlation. However, the effect on blood velocity and flow rate did not present any significant difference. The S-ALE method used in this paper can rapidly generate fluid domains, providing technical support for the development of personalized medicine in the cardiovascular field.