Possible Approaches to Studying the Influence of Magnetic Fields and Mechanical Effects on the Physicochemical Properties of Aqueous IgG Colloids
Source abstract
Abstract
The influence of various mechanical influences (transfusion, stirring, vibration, shaking, etc.) and magnetic installations (used in the application of spin chemistry methods) on colloidal solutions of protein and water, which are often used in pharmaceutical production, was studied. It has been shown that when mechanical influences are applied, physical and chemical properties of water and aqueous colloids of the IgG protein are changed. Magnetic fields do not have a significant effect on water; however, variation in a number of physical and chemical characteristics is observed in protein colloids. Moreover, the effect after exposure to magnetic fields with a frequency of 8 Hz is higher compared to the effect after exposure to magnetic fields with a frequency of 50 Hz. This effect persists even at extremely low concentrations of IgG protein molecules. The measurement system proposed in this work makes it possible to monitor the state of protein molecules in a non-invasive mode. In the future, optical and potentiometric methods built into flow systems can be used at all stages of the production of protein pharmaceuticals.
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Research context
OpenAlex topics: Chemical and Physical Studies · Magnetic and Electromagnetic Effects · Biofield Effects and Biophysics
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Prokhorov General Physics Institute of the Russian Academy of Sciences, 119991 Moscow, Russia
Department of Biophysics, Belarusian State University, 220030 Minsk, Belarus
Institute of Fertility of Soils of South Russia, 346493 Persianovka, Russia
Department of Fundamental Sciences, Bauman Moscow State Technical University, 105005 Moscow, Russia
Funding
Ministry of Science and Higher Education of the Russian Federation
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