DataVXApplied SciencesPaper
journal article·2023-11-27Open access

Peripheral Giant Cell Granuloma in Pregnancy: A Case Report

Francisco Javier Alcaraz Baturoni, José Sergio Zepeda Nuño, Brenda Fernanda Nolasco González, Moisés Ramos Solano, Melissa Martínez Nieto, Sarah Monserrat Lomelí Martínez

Applied Sciences· Volume 13· Issue 23
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Abstract

Peripheral giant cell granuloma (PGCG) is an asymptomatic, non-neoplastic, and proliferative lesion of unknown etiology. Possible pre-disposing factors, such as hormonal changes during pregnancy, have been suggested. However, the association between PGCG and pregnancy is controversial. There are few reported clinical cases of pregnancy-associated PGCG in the literature, and they occurred only in the lower jaw. The present report is on a 35-year-old female patient at 36 weeks of gestation who presented with a PGCG in the central and lateral incisors of the upper jaw. Management consisted of complete surgical excision of the lesion along with a margin of healthy tissue under local anesthesia, followed by curettage of the adjacent fibers of the affected bony wall. The patient experienced adequate healing without complications. The diagnosis of PGCG was based on clinical characteristics, imaging examinations, and histopathological confirmation. The patient underwent postoperative follow-up evaluations at 3, 6, and 12 months, and there were no signs of recurrence.
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Research context

OpenAlex topics: Oral and Maxillofacial Pathology · Bone Tumor Diagnosis and Treatments · Reconstructive Facial Surgery Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Periodontics Program, Department of Integral Dentistry Clinics, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico

Microbiology and Pathology Department, Pathology Laboratory, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico

Independent Researcher, Guadalajara 44340, Jalisco, Mexico

Instituto de Investigación en Cáncer de la Infancia y la Adolescencia (INICIA), Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico

Department of Medical and Life Sciences, Centro Universitario de la Ciénega, Universidad de Guadalajara, Ocotlán 47810, Jalisco, Mexico

Master of Public Health Program, Department of Wellbeing and Sustainable Development, Centro Universitario del Norte, Universidad de Guadalajara, Colotlán 46200, Jalisco, Mexico

Prostodontics Program, Department of Integral Dentistry Clinics, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico

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