Development of a Personalized and Low-Cost 3D-Printed Liver Model for Preoperative Planning of Hepatic Resections
Source abstract
Abstract
Three-dimensional (3D) printing offers new opportunities in surgical planning and medical education, yet high costs and technological complexity often limit its widespread use, especially in low-resource settings. This study presents a personalized, cost-effective, and anatomically accurate liver model designed using open-source tools and affordable 3D-printing techniques. Segmentation of hepatic CT images was performed in 3D Slicer using a region-growing method, and the resulting models were optimized and exported as STL files. The external mold was printed with Fused Deposition Modeling (FDM) using PLA+, while internal structures such as vessels and tumors were fabricated via Liquid Crystal Display (LCD) printing using PLA Pro resin. The final assembly was cast in food-grade gelatin to mimic liver tissue texture. The complete model was produced for under USD 50, with an average total production time of under 128 h. An exploratory pedagogical evaluation with five medical trainees yielded high Likert scores for anatomical understanding (4.6), spatial awareness (4.4), planning confidence (4.2), and realism (4.4). This model demonstrated utility in preoperative discussions and training simulations. The proposed workflow enables the fabrication of low-cost, realistic hepatic phantoms suitable for education and surgical rehearsal, promoting the integration of 3D printing into everyday clinical practice.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Anatomy and Medical Technology · Surgical Simulation and Training · Advanced Radiotherapy Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Energy-Materials-Instrumentation and Telecom Laboratory (EMIT), Faculty of Science and Technology, University Hassan 1st, Settat 26002, Morocco
Sciences and Engineering of Biomedicals, Biophysics and Health Laboratory, Higher Institute of Health Sciences (ISSS), University Hassan 1st, Settat 26002, Morocco
References (25)
Show source-provided references
1. WHO (2025, July 13). Global Cancer Observatory. Available online: Https://Gco.Iarc.Fr/Today.
2. Hepatocellular Carcinoma10.1056/NEJMra1001683 ↗
3. Foreword10.1159/000438471 ↗
4. Two-Stage Hepatectomy: A Planned Strategy to Treat Irresectable Liver Tumors10.1097/00000658-200012000-00006 ↗
5. 3D Printing Based on Imaging Data: Review of Medical Applications10.1007/s11548-010-0476-x ↗
6. 3D Printout Models vs. 3D-Rendered Images: Which Is Better for Preoperative Planning?10.1016/j.jsurg.2016.01.003 ↗
7. Do 3D Printing Models Improve Anatomical Teaching About Hepatic Segments to Medical Students? A Randomized Controlled Study10.1007/s00268-016-3541-y ↗
8. Advantages and Disadvantages of 3-Dimensional Printing in Surgery: A Systematic Review10.1016/j.surg.2015.12.017 ↗
9. Cost-Effective, Personalized, 3D-Printed Liver Model for Preoperative Planning before Laparoscopic Liver Hemihepatectomy for Colorectal Cancer Metastases10.1007/s11548-017-1527-3 ↗
10. Use of 3D Printing for Medical Education Models in Transplantation Medicine: A Critical Review10.1007/s40472-016-0088-7 ↗
11. Review of 3D Printing Applications in Biomedical Engineering: A Comprehensive Analysis10.58739/jcbs/v14i4.110 ↗
12. Meyer-Szary, J., Luis, M., Mikulski, S., Patel, A., Schulz, F., Tretiakow, D., Fercho, J., Jaguszewska, K., Frankiewicz, M., and Pawłowska, E. (2022). The Role of 3D Printing in Planning ComplexMedical Procedures and Training of Medical Professionals—Cross-Sectional Multispecialty Review. Int. J. Env. Res. Public Health, 19.10.3390/ijerph19063331 ↗
13. Clinical Efficacy and Effectiveness of 3D Printing: A Systematic Review10.1136/bmjopen-2017-016891 ↗
14. The Role of 3D Printing in Anatomy Education and Surgical Training: A Narrative Review10.15694/mep.2017.000092 ↗
15. Wu, S., Zeng, J., Li, H., Han, C., Wu, W., Zeng, W., and Tang, L. (2023). A Review on the Full Chain Application of 3D Printing Technology in Precision Medicine. Processes, 11.10.3390/pr11061736 ↗
16. Jiang, Y., Jiang, H., Yang, Z., and Li, Y. (2024). The Current Application of 3D Printing Simulator in Surgical Training. Front. Med., 11.10.3389/fmed.2024.1443024 ↗
17. Three-Dimensional Print of a Liver for Preoperative Planning in Living Donor Liver Transplantation10.1002/lt.23729 ↗
18. Medical Applications for 3D Printing: Current and Projected Uses
19. Accuracy in Quantitative 3D Image Analysis10.1105/tpc.114.135061 ↗
20. A Low-Cost Surgical Application of Additive Fabrication10.1016/j.jsurg.2013.10.012 ↗
21. Cost-Effective Three-Dimensional Printing of Visibly Transparent Microchips within Minutes10.1021/ac4041857 ↗
22. Personalized 3D Printed Model of Kidney and Tumor Anatomy: A Useful Tool for Patient Education10.1007/s00345-015-1632-2 ↗
23. Application of a Three-Dimensional Print of a Liver in Hepatectomy for Small Tumors Invisible by Intraoperative Ultrasonography: Preliminary Experience10.1007/s00268-014-2740-7 ↗
24. Luque, M.C., Calleja-Hortelano, A., and Romero, P.E. (2019). Use of 3D Printing in Model Manufacturing for Minor Surgery Training of General Practitioners in Primary Care. Appl. Sci., 9.10.3390/app9235212 ↗
25. Three-Dimensional Printed Moulds to Obtain Silicone Hearts with Congenital Defects for Paediatric Heart-Surgeon Training10.1093/ejcts/ezae079 ↗