journal article·2024-12-17Open access

Potential Impacts of Artificial Intelligence (AI) in Biotechnology

Alexandrina Gomes, Beatriz Gonçalves, Bruno Inglês, Sara Silvério, Carlos A. Pinto, Jorge A. Saraiva

Applied Sciences· Volume 14· Issue 24

Abstract

The impact of artificial intelligence (AI) in biotechnology has become increasingly significant, driving advancements across multiple subfields in several areas of science. The demand for faster data analysis, integration of extensive databases, pattern recognition, problem solving, and even hypothesis generation has fueled the development of AI technologies in subjects like modern biotechnology, which AI has revolutionized, where the main goal is to develop new advanced products and technologies through the manipulation of biological organisms. The main impacts of AI observed in biotechnology are focused on four colors of biotechnology: green (agricultural sector); red (health sector); white (industries); and blue (marine sector). Numerous AI tools have been developed and made freely available, significantly reducing researchers’ workloads. However, the application of AI in biotechnology also raises questions that must be addressed. This review exhibits and discusses the impacts of AI on biotechnology, the advantages and disadvantages of its current presence, and the potential ethical issues and social impacts.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Genetics, Bioinformatics, and Biomedical Research · Biomedical and Engineering Education

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal

LAQV-REQUIMTE, Chemistry Department, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal

Funding

FCT/MCTES

References (73)

Show source-provided references
1. History of Artificial Intelligence
2. Computational Intelligence
3. Introduction to Artificial Neural Network
4. A Proposal for the Dartmouth Summer Research Project on Artificial Intelligence, 31 August 1955
5. Giattino, C., Mathieu, E., Samborska, V., and Roser, M. (2024, March 18). Artificial Intelligence. Available online: https://ourworldindata.org/artificial-intelligence#introduction.
6. A Review of AI Teaching and Learning from 2000 to 202010.1007/s10639-022-11491-w ↗
7. Artificial Intelligence, Machine Learning and Deep Learning in Advanced Robotics, a Review10.1016/j.cogr.2023.04.001 ↗
8. Vashishth, T.K., Chaudhary, S., Kumar, B., Kumar, S., Sharma, V., and Sharma, K.K. (2023). The Evolution of Ai and Its Transformative Effects on Computing: A Comparative Analysis. Intell. Eng. Appl. Appl. Sci. Sustain., 425–442.10.4018/979-8-3693-0044-2.ch022 ↗
9. Lederberg, J., Feigenbaum, E., Levinthai, E., and Rindfleisch, T. (1974). SUMEX—A Resource for Applications of Artificial Intelligence in Medicine. Proceedings of the 1974 Annual ACM Conference, San Diego, CA, USA, November 1974, ACM.10.1145/1408800.1408907 ↗
10. Extremozymes: Challenges and Opportunities on the Road to Novel Enzymes Production10.1016/j.procbio.2024.04.035 ↗
11. Clark, D., and Pazdernik, N. (2015). Biotechnology, Academic Cell.10.1016/B978-0-12-385015-7.00007-7 ↗
12. AI for Life: Trends in Artificial Intelligence for Biotechnology10.1016/j.nbt.2023.02.001 ↗
13. Machine Learning in Bioprocess Development: From Promise to Practice10.1016/j.tibtech.2022.10.010 ↗
14. Zimmerman, M.R. (2018). Teaching AI: Exploring New Frontiers for Learning, International Society for Technology in Education.
15. (2024, May 14). Telus How Do You Train Artificial Intelligence (AI)?. Available online: https://www.telusinternational.com/insights/ai-data/article/how-to-train-ai.
16. Machine Learning Advancements in Organic Synthesis: A Focused Exploration of Artificial Intelligence Applications in Chemistry10.1016/j.aichem.2024.100049 ↗
17. How Artificial Intelligence Is Changing Drug Discovery Spotlight10.1038/d41586-018-05267-x ↗
18. Swinney, D.C. (2024, May 27). Old Methods for New Drugs. Available online: https://www.aljazeera.com/opinions/2011/12/8/old-methods-for-new-drugs.
19. Lu, J., Miller, K., Smith, I., and Warren, G. (2024, May 27). Traditional Drug Development Process. Available online: https://www.theactuarymagazine.org/traditional-drug-development-process/.
20. The Mechanism of Action of Aspirin10.1016/S0049-3848(03)00379-7 ↗
21. The First 3500 Years of Aspirin History from Its Roots—A Concise Summary10.1016/j.vph.2018.10.008 ↗
22. First-Generation Agents: Aspirin, Heparin and Coumarins10.1016/j.beha.2004.03.003 ↗
23. Playing with AI to Investigate Human-Computer Interaction Technology and Improving Critical Thinking Skills to Pursue 21st Century Age10.1155/2022/6468995 ↗
24. Fairbank, A. (2024, May 27). How AI Is Shaping the Future of Biotechnology. Available online: https://averyfairbank.com/how-ai-is-shaping-the-future-of-biotechnology/.
25. Integrating Artificial Intelligence and High-Throughput Phenotyping for Crop Improvement10.1016/j.jia.2023.10.019 ↗
26. Selvanarayanan, R., Rajendran, S., Algburi, S., Ibrahim Khalaf, O., and Hamam, H. (2024). Empowering Coffee Farming Using Counterfactual Recommendation Based RNN Driven IoT Integrated Soil Quality Command System. Sci. Rep., 14.10.1038/s41598-024-56954-x ↗
27. Enhanced Detection Algorithm for Apple Bruises Using Structured Light Imaging
28. Awais, M., Mahum, R., Zhang, H., Zhang, W., Mohammed Metwally, A.S., Hu, J., and Arshad, I. (2024). Short-Term Photovoltaic Energy Generation for Solar Powered High Efficiency Irrigation Systems Using LSTM with Spatio-Temporal Attention Mechanism. Sci. Rep., 14.10.1038/s41598-024-60672-9 ↗
29. Artificial Intelligence in Healthcare and Biotechnology: A Review of the Saudi Experience
30. Advances in Artificial Intelligence (AI)-Assisted Approaches in Drug Screening10.1016/j.aichem.2023.100039 ↗
31. High-Throughput Proteomics and AI for Cancer Biomarker Discovery10.1016/j.addr.2021.113844 ↗
32. Health Research in the Era of Artificial Intelligence: Advances in Gene-Editing Study10.1016/j.medp.2024.100027 ↗
33. Convergence of CRISPR and Artificial Intelligence: A Paradigm Shift in Biotechnology10.1016/j.humgen.2024.201297 ↗
34. Deep Aging Clocks: The Emergence of AI-Based Biomarkers of Aging and Longevity10.1016/j.tips.2019.05.004 ↗
35. Artificial Intelligence for Aging and Longevity Research: Recent Advances and Perspectives10.1016/j.arr.2018.11.003 ↗
36. Longevity Pharmacology Comes of Age10.1016/j.drudis.2021.02.015 ↗
37. Briggs, H. (2024, May 31). One of Biology’s Biggest Mysteries “Largely Solved” by AI. Available online: https://www.bbc.com/news/science-environment-55133972.
38. Jumper, J., Evans, R., Pritzel, A., Green, T., Figurnov, M., Tunyasuvunakool, K., Ronneberger, O., Bates, R., and Žídek, A. (2024, May 31). AlphaFold: A Solution to a 50-Year-Old Grand Challenge in Biology. Available online: https://deepmind.google/discover/blog/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology/.
39. Sample, I. (2024, May 31). DeepMind AI Cracks 50-Year-Old Problem of Protein Folding. Available online: https://www.theguardian.com/technology/2020/nov/30/deepmind-ai-cracks-50-year-old-problem-of-biology-research.
40. White Biotechnology: State of the Art Strategies for the Development of Biocatalysts for Biorefining10.1016/j.biotechadv.2015.08.004 ↗
41. Analysing the Connection Between AI and Industry 4.0 from a Cybersecurity Perspective: Defending the Smart Revolution
42. Sahai, A.K., and Rath, N. (2021). Artificial Intelligence and the 4th Industrial Revolution. Artificial Intelligence and Machine Learning in Business Management: Concepts, Challenges, and Case Studies, CRC Press.10.1201/9781003125129-8 ↗
43. Artificial Intelligence Approach for High Level Production of Amylase Using Rhizopus Microsporus Var. Oligosporus and Different Agro-Industrial Wastes10.1002/jctb.5054 ↗
44. Artificial Intelligence in the Creative Industries: A Review10.1007/s10462-021-10039-7 ↗
45. Applications of Artificial Intelligence (AI) in Cannabis Industries: In Vitro Plant Tissue Culture10.51584/IJRIAS.2023.8703 ↗
46. Amore, A., and Philip, S. (2023). Artificial Intelligence in Food Biotechnology: Trends and Perspectives. Front. Ind. Microbiol., 1.10.3389/finmi.2023.1255505 ↗
47. Exploring Blockchain and Artificial Intelligence in Intelligent Packaging to Combat Food Fraud: A Comprehensive Review10.1016/j.fpsl.2024.101287 ↗
48. Prabha, S.P., Nagappan, S., Rathna, R., Viveka, R., and Nakkeeran, E. (2020). Blue Biotechnology: A Vision for Future Marine Biorefineries. Refining Biomass Residues for Sustainable Energy and Bioproducts: Technology, Advances, Life Cycle Assessment, and Economics, Academic Press.10.1016/B978-0-12-818996-2.00021-1 ↗
49. Vermelho, B., Maldonado-Ruiz, K., Pedroza-Islas, R., and Pedraza-Segura, L. (2024). Blue Biotechnology: Marine Bacteria Bioproducts. Microorganisms, 12.10.3390/microorganisms12040697 ↗
50. Improvement of Nutritional Quality of Live Feed for Aquaculture: An Overview10.1111/are.14357 ↗
51. Mayekar, T., Salgaonkar, A.A., Koli, J.M., Patil, P.R., Chaudhari, A., Pawar, N., Kamble, S., Giri, A., Phadke, G.G., and Kapse, P. (2024, October 20). Biotechnology and Its Applications in Aquaculture and Fisheries. Available online: https://www.researchgate.net/publication/336982982_biotechnology_and_its_applications_in_aquaculture_and_fisheries.
52. Applications of Environment Biotechnology in Aquaculture-Review
53. Saeed, A.F.U.H., Su, J., and Ouyang, S. (2021). Marine-Derived Drugs: Recent Advances in Cancer Therapy and Immune Signaling. Biomed. Pharmacother., 134.10.1016/j.biopha.2020.111091 ↗
54. Sustainable Aquaculture Development: A Review on the Roles of Cloud Computing, Internet of Things and Artificial Intelligence (CIA)10.1111/raq.12559 ↗
55. Exploring Opportunities of Artificial Intelligence in Aquaculture to Meet Increasing Food Demand10.1016/j.fochx.2024.101309 ↗
56. Awan, J. Artificial Intelligence Applications to Critical Transportation Issues. Proceedings of the Artificial Intelligence Applications to Critical Transportation Issues.
57. Kalla, D., Kuraku, S., and Samaah, F. (2023). Advantages, Disadvantages and Risks Associated with ChatGPT and AI on Cybersecurity. J. Emerg. Technol. Innov. Res., 10.
58. Advantages and disadvantages of artificial intelligence and machine learning: A literature review
59. Karim, L., Gianluca, Q., Anna, T.G., and Catherine, G. (2022). European Parliament. Directorate-General for Parliamentary Research Services. Artificial Intelligence in Healthcare: Applications, Risks, and Ethical and Societal Impacts, Springer Nature.
60. Elliott, D., and Soifer, E. (2022). AI Technologies, Privacy, and Security. Front. Artif. Intell., 5.10.3389/frai.2022.826737 ↗
61. Transparency and the Black Box Problem: Why We Do Not Trust AI10.1007/s13347-021-00477-0 ↗
62. Could ChatGPT Help You to Write Your next Scientific Paper?: Concerns on Research Ethics Related to Usage of Artificial Intelligence Tools10.5125/jkaoms.2023.49.3.105 ↗
63. Pervez, N., and Titus, A.J. (2024). Integrating MLSecOps in the Biotechnology Industry 5.0, IntechOpen.10.5772/intechopen.114972 ↗
64. Leffer, L. (2024, May 27). The AI Boom Could Use a Shocking Amount of Electricity. Available online: https://www.scientificamerican.com/article/the-ai-boom-could-use-a-shocking-amount-of-electricity/.
65. European Parliament: Directorate-General for Parliamentary Research Services, and De Baerdemaeker, J. (2023). Artificial Intelligence in the Agri-Food Sector: Applications, Risks and Impacts, European Parliament. Available online: https://data.europa.eu/doi/10.2861/516636.
66. Torresen, J. (2018). A Review of Future and Ethical Perspectives of Robotics and AI. Front. Robot. AI, 4.10.3389/frobt.2017.00075 ↗
67. Dixit, S., Kumar, A., Srinivasan, K., Vincent, P.M.D.R., and Ramu Krishnan, N. (2023). Advancing Genome Editing with Artificial Intelligence: Opportunities, Challenges, and Future Directions. Front. Bioeng. Biotechnol., 11.10.3389/fbioe.2023.1335901 ↗
68. Beyond the Turing Test
69. Armstrong, S., and Sotala, K. (2015). How We’re Predicting AI—Or Failing To. Beyond Artificial Intelligence, Springer Nature.10.1007/978-3-319-09668-1_2 ↗
70. The Transformative Potential of Artificial Intelligence10.1016/j.futures.2021.102884 ↗
71. Roser, M. (2024, June 03). AI Timelines: What Do Experts in Artificial Intelligence Expect for the Future?. Available online: https://ourworldindata.org/ai-timelines?ref=lite.improvethenews.org.
72. Grace, K., Stewart, H., Sandkühler, J.F., Thomas, S., Weinstein-Raun, B., and Brauner, J. (2024). Thousands of AI authors on the future of AI. arXiv.
73. Iram, A., Dong, Y., and Ignea, C. (2024). Synthetic Biology Advances towards a Bio-Based Society in the Era of Artificial Intelligence. Curr. Opin. Biotechnol., 87.10.1016/j.copbio.2024.103143 ↗