Endothelial Reprogramming in Sports Traumatology: Role of the Widespread Neuro-Immuno-Endocrine-Endothelial System
Source abstract
Abstract
This paper deals with the role of the widespread neuro-immuno-endocrine-endothelial system in sport traumatology. The aim of this work is to see if sport or regular physical activity is able to reprogram the endothelium, to advance the new concept of neuro-immuno-endocrine-endothelial diffused system, and to introduce in the practice of sport medicine a new test in the fields of “Athlete functional evaluation” and “Sports fitness”. The first object of this paper is to see whether sport or regular physical activity can change the functional structure of the endothelium. The second goal is to frame under a general view the knowledge and individual lines of research on endothelium, to highlight what we believe is, in the organization of homeostasis, the location of this ‘organ’, namely in the neuro-immune-endocrine system spread.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: High Altitude and Hypoxia · Nitric Oxide and Endothelin Effects · Traumatic Brain Injury and Neurovascular Disturbances
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Medicine and Surgery, University of Enna “Kore”, 94100 Enna, Italy
Department of Human and Social Sciences, University of Enna “Kore”, 94100 Enna, Italy
Department of Surgery and Medical-Surgical Specialties, Univesity of Catania, 95123 Catania, Italy
References (39)
Show source-provided references
1. Integrated cardiac, renal and endocrine actions of endothelin10.1172/JCI113876 ↗
2. Endothelin: A new challenge10.1021/jm00087a001 ↗
3. The History of Endocrinology: (Section of the History of Medicine)
4. Gut Microbiota and the Neuroendocrine System10.1007/s13311-017-0600-5 ↗
5. Air Pollution-Induced Vascular Dysfunction: Potential Role of Endothelin-1 (ET-1) System10.1007/s12012-015-9334-y ↗
6. Endothelin-1-induced endothelial microvesicles impair endothelial cell function10.1152/japplphysiol.00816.2019 ↗
7. N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine10.1016/S0021-9258(18)38112-2 ↗
8. Shear Stress Mediates Endothelial Adaptations to Exercise Training in Humans10.1161/HYPERTENSIONAHA.109.146282 ↗
9. Considerazioni cliniche sugli effetti dell’esercizio fisico nella risposta immunitaria di soggetti sani e degli uremici
10. The Effect of Physical Exercise on Endothelial Function10.2165/11317750-000000000-00000 ↗
11. Exercise training enhances endothelial function in young men10.1016/S0735-1097(99)00036-4 ↗
12. Guyton Arthur, C. (1995). Trattato di Fisiologia Medica, PICCIN.
13. Dalla Volta, S. (1996). Malattie del Cuore e dei Vasi, McGraw-Hill.
14. Endothelial Functions10.1161/ATVBAHA.117.309813 ↗
15. Molecular effects of exercise training in patients with cardiovascular disease: Focus on skeletal muscle, endothelium, and myocardium10.1152/ajpheart.00470.2016 ↗
16. Tremblay, J.C., and Pyke, K.E. (2019). Exercise and the Endothelium. Cardiorespiratory Fitness in Cardiometabolic Diseases, Springer.10.1007/978-3-030-04816-7_6 ↗
17. Effects of prolonged endurance exercise on vascular endothelial and inflammation markers
18. Beyond organoids: In vitro vasculogenesis and angiogenesis using cells from mammals and zebrafish10.1016/j.reprotox.2017.07.002 ↗
19. Behavior of repolarization variables during exercise test in the athlete’s heart10.1111/j.1542-474X.2012.00495.x ↗
20. Significance of plasma nitric oxide/endothelial-1 ratio for prediction of coronary artery disease10.1177/000331970505600304 ↗
21. Current views on the paraneurone concept10.1016/0166-2236(79)90013-4 ↗
22. The endothelium and its role in regulating vascular tone10.2174/1874192401004010302 ↗
23. Dejana, E., and Prosdocimi, M. (1991). Il Laboratorio Endoteliale, Il Pensiero Scientifico Editore.
24. Rossi, G.P., Zanin, L., Dal Palù, C., and Cesari, M. (1995). L’ Endotelina Nella Fisiologia e Nella Patologia, Federazione Medica.
25. Physical Training Increases eNOS Vascular Expression and Activity and Reduces Restenosis After Balloon Angioplasty or Arterial Stenting in Rats10.1161/01.RES.0000046233.94299.D6 ↗
26. Enhanced endothelial activity reflected in cutaneous blood flow oscillations of athletes10.1007/s00421-003-0867-6 ↗
27. Effect of exercise on chosen parameters of endothelium function in middle age health humans
28. Zawadzki10.1038/288373a0 ↗
29. The role of potassium channels in the endothelial dysfunction induced by periodontitis10.1590/1678-7757-2018-0048 ↗
30. Endothelial Activation
31. Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men10.1016/j.amjhyper.2004.11.006 ↗
32. Martini, L., and Ganong, W.F. (2013). Neuroendocrinology: Volume II, Academic Press.
33. The mechanism of pancreatic secretion10.1113/jphysiol.1902.sp000920 ↗
34. Novel Electrocardiographic Parameters of Altered Repolarization in Uncomplicated Overweight and Obesity10.1038/oby.2010.252 ↗
35. Physical exercise is terapy–L’attività motoria è terapia
36. Functional evaluation of the diabetic athlete: Role of the sports doctor
37. Abrignani, G., Braschi, A., di Girolamo, P., Francavilla Vincenzo Cristian, N., Renda, A., Di Girolamo, G., and Francavilla, S. (2010). Novo. Il TPE/QT ratio nell’obesità complicate o meno da cardiopatia ischemica cronica. G. Ital. Cardiol., ISSN: 1972-6481.
38. Endothelins10.1096/fasebj.5.12.1916094 ↗
39. Role of the endocardial endothelium in the regulation of myocardial function. Physiologic and pathophysiologic implications10.1097/00000542-199312000-00027 ↗