An In-Vitro Evaluation of Toxic Metals Concentration in the Third Molars from Residents of the Legnica-Głogów Copper Area and Risk Factors Determining the Accumulation of Those Metals: A Pilot Study
Source abstract
Abstract
The purpose of this study was to determine tissue concentration of toxic metals, namely Mn, Cr, Ni, Cu, Fe, Cd, Pb, and Zn, in the removed third molars in patients from the Legnica-Głogów copper district. A group of 69 patients with an average age of 27.3 ± 6.9 years was enrolled into the study. There were 16 (23.2%) men and 53 (76.8%) women. Patients were divided into two groups according to the place of residence—residents of the Legnica-Głogów Copper Area (n = 49) and the control group, residents of Wrocław (n = 20). Determination of the Pb, Cd, Cr, Ni, Fe, Mn, Cu, Zn content was performed by atomic absorption spectrometry in an air–acetylene flame using the SpectraAA atomic absorption spectrometer with a V2 AA240FS flame attachment. The content of Fe and Pb in the third molars was higher among residents of the Legnica-Głogów Copper Area (p = 0.016 and p = 0.002, respectively). The significant risk factors that may contribute to the accumulation of toxic metals in teeth were identified. We showed a significant correlation between the level of Cr, Cu, and Zn and age, and between chromium and vitamin D3 concentration in the blood (p < 0.05 for all).
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Research context
OpenAlex topics: Heavy Metal Exposure and Toxicity · Mercury impact and mitigation studies · Heavy metals in environment
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Academic Dental Polyclinic of Dental Center of Technology Transfer Ltd., Krakowska 26, 50-425 Wroclaw, Poland
Department of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland
Department of Prosthetic Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland
Department of Human Nutrition, Wroclaw University of Environmental and Life Sciences, Chelmonskiego 37/41, 51-630 Wroclaw, Poland
Department of Basic Sciences, Wroclaw Medical University, Chalubinskiego 3, 50-368 Wroclaw, Poland
Department of Dental Surgery, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland
Department of Biostructure and Animal Physiology, Wrocław University of Environmental and Life Sciences, Kożuchowska 1/3, 51-631 Wroclaw, Poland
Funding
Wroclaw Medical University · Faculty of Veterinary Medicine and the Faculty of Biotechnology and Food Science, Wrocław University of Environmental and Life Sciences
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