Manufacture and Characterization of Alginate-CMC-Dextran Hybrid Double Layer Superabsorbent Scaffolds
Source abstract
Abstract
This study focused on the manufacturing of functional superabsorbent sponges using natural polymers. An alginate/CMC-embedded dextran hybrid dual-layer formulation was prepared using the freeze-drying method. The physical properties of the formulation were characterized using a field emission scanning electron microscope and a universal testing machine, and the swelling ratio was calculated. Cell viability assays were performed using keratinocytes (HaCaT cells). The results showed that this formulation can absorb a large amount of moisture and provide morphological stability through its tensile strength and uniform porosity, and this was verified by its biocompatibility. We believe that in the future, by combining this novel hybrid dual-layer superabsorbent sponge with antibacterial agents with excellent porosity, it would serve as a medical material for producing bandages that can absorb blood and body fluids, feminine hygiene products, and functional antibacterial masks.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Hydrogels: synthesis, properties, applications · Electrospun Nanofibers in Biomedical Applications · Wound Healing and Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Advanced Mechatronics R&D Group, Daegyeong Division, Korea Institute of Industrial Technology (KITECH), 320 Technosunhwan-ro, Yuga-eup, Dalseong-gun, Daegu 42994, Korea
Advanced Energy Materials and Components R&D Group, Dongnam Division, Korea Institute of Industrial Technology (KITECH), 804 Baekyang-daero, Sasang-gu, Busan 46938, Korea
References (17)
Show source-provided references
1. Superabsorbent polymer (SAP) hydrogels for protein enrichment10.1016/j.seppur.2015.04.024 ↗
2. Eco-Friendly and biocompatible cross-linked carboxymethylcellulose hydrogels as adsorbents for the removal of organic dye pollutants for environmental applications10.1080/09593330.2017.1367845 ↗
3. Synthesis of a new superabsorbent copolymer based on acrylic acid grafted onto carboxymethyl tragacanth10.1016/j.carbpol.2018.08.094 ↗
4. Synthesis and swelling properties of protein-poly (acrylic acid-co-acrylamide) superabsorbent composite10.1002/pc.21077 ↗
5. Synthesis of superabsorbent polymers based on chitosan derivative graft acrylic acid-co-acrylamide and its property testing10.1016/j.ijbiomac.2019.03.176 ↗
6. Calcium alginate gel fibers: Influence of alginate source and gel structure on fiber strength10.1002/app.1994.070511010 ↗
7. The conversion of calcium alginate fibers into alginic Acid fibers and sodium alginate fibers10.1002/app.24524 ↗
8. Polysaccharide hydrogels for protein drug delivery10.1016/0144-8617(95)00080-1 ↗
9. Dextran hydrogel scaffolds enhance angiogenic responses and promote complete skin regeneration during burn wound healing10.1073/pnas.1115973108 ↗
10. Synthesis and properties of carboxymethyl cellulose-graft-poly (acrylic acid-co-acrylamide) as a novel cellulose-based superabsorbent10.1002/app.23948 ↗
11. Biocompatible cellulose-based superabsorbent hydrogels with antimicrobial activity10.1016/j.carbpol.2015.10.057 ↗
12. Jeong, S.I., Park, J.S., Gwon, H.J., An, S.J., Lim, Y.M., Song, B.R., Kim, Y.J., Min, B.H., and Kim, M.S. (2017). Preparation and Characterization of CMC Hydrogels with Porcine Cartilage, The Polymer Society of Korea.10.7317/pk.2017.41.1.151 ↗
13. Control of pore structure and size in freeze-dried collagen sponges10.1002/jbm.1028 ↗
14. Choi, J.Y., Hong, G.S., Kwon, T.K., and Lim, J.O. (2018). Fabrication of Oxygen Releasing Scaffold by Embedding H2O2-PLGA Microspheres into Alginate-Based Hydrogel Sponge and Its Application for Wound Healing. Appl. Sci., 8.10.3390/app8091492 ↗
15. Preparation of High Molecular Weight Atactic Poly(vinyl alcohol) Hydrogel by Electron Beam Irradiation Technique
16. Lee, J., Park, S., Roh, H.G., Oh, S., Kim, S., Kim, M., Kim, D., and Park, J. (2018). Preparation and Characterization of Superabsorbent Polymers Based on Starch Aldehydes and Carboxymethyl Cellulose. Polymers, 10.10.3390/polym10060605 ↗
17. Superabsorbent hydrogels based on cellulose for smart swelling and controllable delivery10.1016/j.eurpolymj.2009.04.033 ↗