Development of an Internet of Things Based Electrochemical Microfluidic System for Free Calcium Detection
Source abstract
Abstract
This paper represents the design, fabrication, and implementation of an Internet of Things (IoT)-based electrochemical microfluidic system for free calcium concentration detection with a 3D printing technique. Free calcium solutions with desired concentrations between 0 and 40 µM can be obtained. The solutions were used to calibrate the system by using an impedance analyzer for monitoring the impedance change to determine the operating frequency. Continuously, an IoT enabled point of care device was used for real-time detection and to send signals to the cloud for sharing. The relationship between the concentration and reactance are y = − 1.3812 Lgx + 0.9809 at a wavelength of 450 Hz, with an R2 of 0.9719. We measured the calcium concentration changing from 39.8 µM to 1.35 µM (nearly real-time) by the PoC device and showed the concentration changes resulting with time on the cell phone app. The results depicted in this paper provide a strong platform for the precise and real-time monitoring of different biomedical samples.
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Research context
OpenAlex topics: Biosensors and Analytical Detection · IoT and Edge/Fog Computing · Microfluidic and Capillary Electrophoresis Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Chemistry and Chemical Engineering, Guang Zhou University, Guangzhou 510006, China
School of Engineering, Macquarie University, Sydney, NSW 2109, Australia
AgResearch Limited, 10 Bisley Street, Hamilton West, Hamilton 3217, New Zealand
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