Formation of Ordered Ionic Salt Agglomerates Through Evaporative Crystallization in Hanging Drop Systems
Source abstract
Abstract
This study introduces novel experimental systems that facilitate the nucleation, growth, aggregation, and agglomeration of ionic salt solutions, leading to structurally and functionally distinctive crystal formations. Through evaporative crystallization in hanging drops—including layered binary solutions—a range of macroscopic agglomerates were produced, such as hollow spheroidal NaCl/NiSO4 structures, octahedral NaCl films, pentagonally arranged CdSO4 spherulites, and NH4Cl dendritic shells. Additionally, NaCl spheroids were used as templates to fabricate carbon-based morphologies and colloidal photonic crystals with convex or concave geometries, which were subsequently analyzed optically. The study reveals that crystallization and self-assembly, whether independently or synergistically applied, can yield complex architectures with potential applications in advanced device manufacturing beyond conventional processing methods.
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Research context
OpenAlex topics: Pickering emulsions and particle stabilization · nanoparticles nucleation surface interactions · Material Dynamics and Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Lasers Department, National Institute for Lasers, Plasma and Radiation Physics, 409 Atomistilor Street, 077125 Bucharest-Magurele, Romania
Academy of Romanian Scientists (AOSR), Ilfov Street 3, 050044 Bucharest, Romania
Geological Institute of Romania, 1 Caransebes Street, 012271 Bucharest, Romania
Funding
the Romanian Minister of Education and Research under the Romanian National Nucleu Program LAPLAS VII
References (100+)
Show source-provided references
1. Self-assembly at all scales10.1126/science.1070821 ↗
2. Beyond molecules: Self-assembly of mesoscopic and macroscopic components10.1073/pnas.082065899 ↗
3. Self-assembly: From crystals to cells10.1039/b819321p ↗
4. Introduction: Molecular Self-Assembly10.1021/acs.chemrev.1c00884 ↗
5. Guided molecular self-assembly: A review of recent efforts10.1088/0964-1726/12/2/315 ↗
6. Recent advances in supramolecular self-assembly derived materials for high-performance supercapacitors10.1039/D3NA00067B ↗
7. Driving Forces of the Self-Assembly of Supramolecular Systems: Partially Ordered Mesophases10.1134/S003602441806016X ↗
8. The forces at work in collodial self-assembly: A review on fundamental interactions between collodial particles10.1002/apj.144 ↗
9. A Review on Colloidal Self-Assembly and their Applications10.2174/1573413712666160530120807 ↗
10. Self-assembly and applications of anisotropic nanomaterials: A review10.1016/j.nantod.2014.12.005 ↗
11. Self-assembly of nanoparticles at interfaces10.1039/b706609k ↗
12. Monodispersed Colloidal Spheres: Old Materials with New Applications10.1002/(SICI)1521-4095(200005)12:10<693::AID-ADMA693>3.0.CO;2-J ↗
13. From colloidal particles to photonic crystals: Advances in self-assembly and their emerging applications10.1039/D0CS00706D ↗
14. To sink, swim, twin, or nucleate: A critical appraisal of crystal aggregation processes10.1130/G46660.1 ↗
15. Klein, C. (2025, March 05). Mineral. Britannica. Available online: https://www.britannica.com/science/mineral-chemical-compound.
16. Crystal Growth in Geology: Patterns on the Rocks
17. Agates, Geodes, Concretions and Orbicules: Self-Organized Zoning and Morphology
18. Introduction to Crystallization of Fine Chemicals and Pharmaceuticals
19. Davey, R., and Garside, J. (2000). From Molecules to Crystallizers—An Introduction to Crystallization, Oxford University Press.10.1093/hesc/9780198504894.001.0001 ↗
20. Classical Nucleation Theory10.1007/978-90-481-3643-8_1 ↗
21. Usual and unusual crystallization from solution10.1016/j.jcrysgro.2010.01.006 ↗
22. The kinetics of crystal growth10.1039/qr9641800001 ↗
23. Crystal growth kinetics10.1016/0025-5416(84)90194-0 ↗
24. Measurement of agglomeration during crystallization: Is the differentiation of aggregates and agglomerates via ultrasonic irradiation possible?10.1016/j.ces.2019.115214 ↗
25. Modelling of multiple-mechanism agglomeration in a crystallization process10.1016/S0032-5910(02)00213-9 ↗
26. Salt Crystallization during Evaporation: Impact of Interfacial Properties10.1021/la8005629 ↗
27. Supersaturation tracking for the development, optimization and control of crystallization processes10.1016/j.cherd.2010.02.010 ↗
28. Estimation of metastable zone width in different nucleation processes10.1016/S0009-2509(00)00450-4 ↗
29. Different modes of heat transfer and crystallization in a drop of NaCl solution: The influence of key factors on the crystallization rate and the heat transfer coefficient10.1016/j.ijthermalsci.2020.106602 ↗
30. Relating induction time and metastable zone width10.1039/C7CE00770A ↗
31. The dependence of evaporation and crystallization kinetics on dynamic and thermal background10.1002/aic.16282 ↗
32. Experimental study of evaporation and crystallization of brine droplets under different temperatures and humidity levels10.1016/j.icheatmasstransfer.2019.104427 ↗
33. Gravity-driven crystallization in protein and NaCl droplets10.1016/j.colsurfa.2024.135821 ↗
34. Characterization of sodium chloride crystals grown in microgravity10.1016/j.jcrysgro.2011.04.001 ↗
35. Evaporation and crystallization of NaCl-water droplets suspended in air by acoustic levitation10.1016/j.ces.2022.117441 ↗
36. Crystallization controlled by the geometry of a surface10.1021/ja9085512 ↗
37. Crystallization at Inorganic-organic Interfaces: Biominerals and Biomimetic Synthesis10.1126/science.261.5126.1286 ↗
38. Crystallization at Interfaces in Food Emulsions—A General Phenomenon
39. Models of Crystallisation in Evaporating Droplets10.1557/PROC-398-637 ↗
40. Studies of the Crystallization and Dissolution of Individual Suspended Sodium Chloride Aerosol Particles10.1021/acs.jpca.4c02158 ↗
41. Preparation of porous particles by liquid–liquid interfacial crystallization10.1016/j.apt.2010.09.012 ↗
42. Crystallization in emulsions10.1016/S1359-0294(02)00080-8 ↗
43. Patterns during Evaporative Crystallization of a Saline Droplet10.1021/acs.langmuir.2c01535 ↗
44. Sperling, M., and Gradzielski, M. (2017). Droplets, Evaporation and a Superhydrophobic Surface: Simple Tools for Guiding Colloidal Particles into Complex Materials. Gels, 3.10.3390/gels3020015 ↗
45. Evaporation from drops containing dissolved solids10.1002/aic.690060104 ↗
46. Sodium chloride crystallization from thin liquid sheets, thick layers, and sessile drops in microgravity10.1016/j.jcrysgro.2015.07.026 ↗
47. Bormashenko, E., Roy, P.K., Shoval, S., and Legchenkova, I. (2020). Interfacial Crystallization within Liquid Marbles. Condens. Matter, 5.10.20944/preprints202009.0616.v1 ↗
48. Li, Q., Wang, Z., Guo, H., Zhao, J., Luo, H., and Huang, X. (2024). A perspective view of salt crystallization from solution in porous media: Morphology, mechanism, and salt efflorescence. Sci. Rep., 14.10.1038/s41598-024-74645-5 ↗
49. Metastability Limit for the Nucleation of NaCl Crystals in Confinement10.1021/jz500090x ↗
50. Evaporation with sodium chloride crystallization in a capillary tube10.1016/j.jcrysgro.2015.04.010 ↗
51. Aggregate Science: From Structures to Properties10.1002/adma.202001457 ↗
52. Mechanical properties of agglomerates10.1016/S0032-5910(01)00318-7 ↗
53. Crystallization from Thin Films on a Hot Plate: A New Approach of Solid Surface Pattering
54. Self-organisation of single-crystals as ripple patterns through laser ablation of ionic salt solutions10.1016/j.apsusc.2017.02.104 ↗
55. Flower-like agglomerates of hydroxyapatite crystals formed on an egg-shell membrane10.1016/j.colsurfb.2010.10.006 ↗
56. Shahidzadeh, N., Schut, M., Desarnaud, J., Prat, M., and Bonn, D. (2015). Salt stains from evaporating droplets. Sci. Rep., 5.10.1038/srep10335 ↗
57. Multifractal Growth of Crystalline NaCl Aggregates in a Gelatin Medium10.1021/cg301499b ↗
58. Complex Pattern Formation in Solutions of Protein and Mixed Salts Using Dehydrating Sessile Droplets10.1021/acs.langmuir.0c01122 ↗
59. Continuous Production of NaCl Spherical Particles via Emulsion Crystallization in Microfluidic Devices10.1021/acs.cgd.3c00973 ↗
60. Model of textural development of layered crystal aggregates10.1127/ejm/12/3/0609 ↗
61. Ring shells obtained from pure water drops evaporating on a soluble substrate10.1016/j.colsurfa.2022.129724 ↗
62. Zhang, X., Chen, H., Wang, Z., Wang, N., and Zang, D. (2023). Evaporation of Saline Droplets on a Superhydrophobic Substrate: Formation of Crystal Shell and “Legs”. Materials, 16.10.3390/ma16145168 ↗
63. Mesocrystals: Inorganic superstructures made by highly parallel crystallization and controlled alignment10.1002/anie.200500496 ↗
64. Rise and side infiltration in opals and porous materials for their skin-free replica synthesis10.1088/2053-1591/aaf9fd ↗
65. Porous Single Crystals of Calcite from Colloidal Crystal Templates: ACC Is Not Required for Nanoscale Templating10.1002/adfm.201001366 ↗
66. Biomineralization inspired crystal growth for biomimetic materials preparation10.1016/j.jcrysgro.2022.127029 ↗
67. Biomineralization strategy: From material manufacturing to biological regulation10.1016/j.giant.2024.100317 ↗
68. Soft crystals-flexible response systems with high structural order10.1002/chem.201805641 ↗
69. A change in the physical state of a non-equilibrium blood plasma protein film in patients with carcinoma10.1134/1.1470608 ↗
70. Facet engineering of ultrathin two-dimensional materials10.1039/D2CS00067A ↗
71. Near-incompressible faceted polymer microcapsules from metal-organic framework templates10.1002/adma.201302442 ↗
72. Design of GaN convex diffractive microlenses10.1016/S0030-3992(02)00073-7 ↗
73. Concave grating and convex mirror double dispersion spectrograph for optical network applications10.1364/AO.36.007822 ↗
74. Sandu, I., Antohe, I., Fleaca, C.T., Dumitrache, F., Urzica, I., Brajnicov, S., Iagaru, R., Sava, B.A., and Dumitru, M. (2024). Shaping in the Third Direction: Self-Assembly of Convex Colloidal Photonic Crystals on an Optical Fiber Tip by Hanging Drop Method. Polymers, 16.10.3390/polym16131931 ↗
75. Sandu, I., Antohe, I., Fleaca, C.T., Dumitrache, F., Urzica, I., and Dumitru, M. (2024). Shaping in the Third Direction: Colloidal Photonic Crystals with Quadratic Surfaces Self-Assembled by Hanging-Drop Method. Polymers, 16.10.3390/polym16131931 ↗
76. Hanging colloidal drop: A new photonic crystal synthesis route10.1016/j.photonics.2018.02.001 ↗
77. Gravitational effect in evaporating binary microdroplets10.1103/PhysRevLett.122.114501 ↗
78. Solutal and Gravitational Effects during Binary Mixture Droplets Evaporation10.1007/s12217-024-10105-z ↗
79. The Influence of Gravity on Single Crystallization in Large Volume Drops10.4236/jcpt.2014.44025 ↗
80. Crystallization Kinetics of Amorphous Materials
81. Comparison of sodium chloride hopper cubes grown under microgravity and terrestrial conditions10.1038/s41526-019-0085-0 ↗
82. Gielen, B., Jordens, J., Thomassen, L.C.J., Braeken, L., and Van Gerven, T. (2017). Agglomeration Control during Ultrasonic Crystallization of an Active Pharmaceutical Ingredient. Crystals, 7.10.3390/cryst7020040 ↗
83. Effect of Evaporation Temperature on the Quality of Colloidal Crystals at the Water—Air Interface10.1021/la025888e ↗
84. Influence of growth parameters on the fabrication of high-quality colloidal crystals via a controlled evaporation self-assembly method10.1016/j.tsf.2010.02.062 ↗
85. Chen, R.-Q., Lu, Q.-Q., Cheng, Q.-D., Ao, L.-B., Zhang, C.-Y., Hou, H., Liu, Y.-M., Li, D.-W., and Yin, D.-C. (2015). An ignored variable: Solution preparation temperature in protein crystallization. Sci. Rep., 5.10.1038/srep07797 ↗
86. Using Temperature To Crystallize Proteins: A Mini-Review10.1021/cg800665b ↗
87. Crystallization of NaCl by fast evaporation of water in droplets of NaCl solutions10.1016/j.foodres.2016.03.030 ↗
88. Infrared (10.6-μm) radiation induced evaporation of large water drops10.1364/JOSA.71.000887 ↗
89. Laser droplet heating: Fast and slow heating regimes10.1364/AO.28.003671 ↗
90. Enhanced Evaporation of Microscale Droplets With an Infrared Laser10.1115/1.4034486 ↗
91. Optical properties of alkali halide crystals10.1088/1742-6596/1697/1/012253 ↗
92. Output couplers of ultra-transparent KCl and NaCl in a pulsed CO2 laser10.1016/0030-3992(89)90105-9 ↗
93. Probing NaCl hydrate formation from aqueous solutions by terahertz time-domain spectroscopy10.1039/D0CP01571G ↗
94. Capturing the Freeze-Drying Dynamics of NaCl Nanoparticles Using THz Spectroscopy10.1021/jacs.8b07828 ↗
95. Faceted structure: A design for desired illumination and manufacture using 3D printing10.1364/OSAC.1.000026 ↗
96. Self-Assembled Three-Dimensional Graphene-Based Polyhedrons Inducing Volumetric Light Confinement10.1021/acs.nanolett.6b05412 ↗
97. Growth of carbon nanotubes in six orthogonal directions on spherical alumina microparticles10.1016/j.carbon.2011.01.060 ↗
98. Synthesis of NaCl single crystals with defined morphologies as templates for fabricating hollow nano/micro-structures10.1039/C4RA15385E ↗
99. Zhang, Z., Feng, J., Jiang, Y., Liu, P., Zhang, Q., Wei, R., Chen, X., and Feng, J. (2018). Self-Sacrificial Salt Templating: Simple Auxiliary Control over the Nanoporous Structure of Porous Carbon Monoliths Prepared through the Solvothermal Route. Nanomaterials, 8.10.3390/nano8040255 ↗
100. Fabrication of Hexagonal Prism-Shaped Double S-Scheme Cu2O@CdS/ZnS Heterojunctions Utilizing Zeolite Templates: Enhanced Photocatalytic Hydrogen Production and Mechanism Insight10.1021/acs.cgd.4c00651 ↗