Spark plasma sintered HA ‐ZnO ultrafine composite: Mechanical, bactericidal, and cytocompatibility properties
Source abstract
Abstract
Abstract Calcium‐phosphate based hydroxyapatite ( HA ) biomaterials are widely being investigated due to their osseointegration property, but those inherently lack antibacterial property. In the present work, wet‐chemically synthesized rod‐shaped zinc oxide (ZnO) is embedded in HA and its role as antibacterial agent without compromising cytocompatability property is established. In particular, HA ‐ xZnO ( x = 0, 5, 10 wt.%) composites were consolidated by spark plasma sintering at 950°C in vacuum. A host of the spectroscopy and microscopy techniques were utilized to analyze the nature of distribution of ZnO as well as surface chemical characteristics. While the bactericidal property is expectedly induced, the elastic modulus as well as cell adhesion property remains uncompromised.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Dental materials and restorations · Dental Implant Techniques and Outcomes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Laboratory for Biomaterials, Materials Research Center Indian Institute of Science Bangalore India
Materials Science and Engineering Yeungnam University Gyeongsangbuk‐do Korea
References (36)
Show source-provided references
1. Basu B · 2017
2. Basu B · 2017
3. Basu B · 2017
4. 10.1002/(SICI)1097-4636(199823)43:3<338::AID-JBM16>3.0.CO;2-B10.1002/(SICI)1097-4636(199823)43:3<338::AID-JBM16>3.0.CO;2-B ↗
5. 10.1126/science.284.5418.131810.1126/science.284.5418.1318 ↗
6. 10.1002/jbm.b.3303110.1002/jbm.b.33031 ↗
7. 10.1007/s12034-014-0839-y10.1007/s12034-014-0839-y ↗
8. 10.1016/j.msec.2011.04.01510.1016/j.msec.2011.04.015 ↗
9. 10.1039/c2tx00012a10.1039/c2tx00012a ↗
10. 10.1088/1468-6996/9/3/03500410.1088/1468-6996/9/3/035004 ↗
11. 10.1111/jace.1238610.1111/jace.12386 ↗
12. A review of mammalian toxicity of ZnO nanoparticles, Nanotechnology
13. 10.1063/1.199266610.1063/1.1992666 ↗
14. 10.1021/cg700730410.1021/cg7007304 ↗
15. 10.1021/jp063312i10.1021/jp063312i ↗
16. 10.1016/j.powtec.2012.12.04510.1016/j.powtec.2012.12.045 ↗
17. 10.1002/jbm.a.3152710.1002/jbm.a.31527 ↗
18. 10.1016/j.msec.2005.11.00410.1016/j.msec.2005.11.004 ↗
19. Preparation and characterization of novel antibacterial nano‐ ceramic‐composites for bone grafting
20. 10.1007/s10853-008-2497-110.1007/s10853-008-2497-1 ↗
21. 10.1002/jbm.b.3194810.1002/jbm.b.31948 ↗
22. 10.1002/jbm.b.3345510.1002/jbm.b.33455 ↗
23. TagaiH AokiH.Preparation of synthetic hydroxyapatite and sintering of apatite ceramics. In:HastingsGW WilliamsDF eds.Mechanical Properties of Biomaterials. Proc. Conf. at Keele Univ. Sept. 1978.Chichester:Wiley;1980. 1978.
24. 10.1016/j.snb.2004.04.08010.1016/j.snb.2004.04.080 ↗
25. 10.1016/S0022-0248(02)01372-610.1016/S0022-0248(02)01372-6 ↗
26. 10.1016/j.wear.2005.02.06410.1016/j.wear.2005.02.064 ↗
27. 10.1016/j.carbon.2010.04.04710.1016/j.carbon.2010.04.047 ↗
28. 10.1016/j.ceramint.2008.11.02810.1016/j.ceramint.2008.11.028 ↗
29. 10.1016/j.msea.2009.02.05210.1016/j.msea.2009.02.052 ↗
30. 10.1002/jbm.b.3173410.1002/jbm.b.31734 ↗
31. 10.1002/cyto.a.2002610.1002/cyto.a.20026 ↗
32. 10.1038/srep3524310.1038/srep35243 ↗
33. 10.1016/j.colsurfb.2012.01.04610.1016/j.colsurfb.2012.01.046 ↗
34. 10.1002/adfm.20080108110.1002/adfm.200801081 ↗
35. 10.1016/j.toxlet.2010.10.00310.1016/j.toxlet.2010.10.003 ↗
36. 10.1016/j.freeradbiomed.2011.08.02510.1016/j.freeradbiomed.2011.08.025 ↗