In Vitro Corrosion Behavior of Zn3Mg0.7Y Biodegradable Alloy in Simulated Body Fluid (SBF)
Source abstract
Abstract
Biodegradable metallic materials represent a new class of biocompatible materials for medical applications based on numerous advantages. Among them, those based on zinc have a rate of degradation close to the healing period required by many clinical problems, which makes them more suitable than those based on magnesium or iron. The poor mechanical properties of Zn could be significantly improved by the addition of Mg and Y. In this research, we analyze the electro-chemical and mechanical behavior of a new alloy based on Zn3Mg0.7Y compared with pure Zn and Zn3Mg materials. Microstructure and chemical composition were investigated by electron microscopy and energy dispersive spectroscopy. The electrochemical corrosion was analyzed by linear polarization (LP), cyclic polarization (CP) and electrochemical impedance spectroscopy (EIS). For hardness and scratch resistance, a microhardness tester and a scratch module were used. Findings revealed that the mechanical properties of Zn improved through the addition of Mg and Y. Zn, Zn-Mg and Zn-Mg-Y alloys in this study showed highly active behavior in SBF with uniform corrosion. Zinc metals and their alloys with magnesium and yttrium showed a moderate degradation rate and can be considered as promising biodegradable materials for orthopedic application.
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Research context
OpenAlex topics: Magnesium Alloys: Properties and Applications · Corrosion Behavior and Inhibition · Aluminum Alloys Composites Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Faculty of Materials Science and Engineering, “Gh. Asachi” Technical University from Iasi, 700050 Iasi, Romania
Faculty of Dental Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania
Faculty of Mechanical Engineering, “Gh. Asachi” Technical University from Iasi, 700050 Iasi, Romania
Funding
Gheorghe Asachi Technical University of Iași
References (39)
Show source-provided references
1. Design biodegradable Zn alloys: Second phases and their significant influences on alloy properties
2. Evolution of Mg–Zn second phases during ECAP at different processing temperatures and its impact on mechanical properties of Zn-1.6Mg (wt.%) alloys10.1016/j.jallcom.2019.151987 ↗
3. Effect of exposure time on corrosion behavior of zinc-alloy in simulated body fluid solution: Electrochemical and surface investigation10.1016/j.jmrt.2020.12.050 ↗
4. Xue, P., Ma, M., Li, Y., Li, X., Yuan, J., Shi, G., Wang, K., and Zhang, K. (2020). Microstructure, Mechanical Properties, and In Vitro Corrosion Behavior of Biodegradable Zn-1Fe-xMg Alloy. Materials, 13.10.3390/ma13214835 ↗
5. Corrosion behavior of biodegradable metals in two different simulated physiological solutions: Comparison of Mg, Zn and Fe10.1016/j.corsci.2021.109278 ↗
6. Updates on the research and development of absorbable metals for biomedical applications10.1007/s40204-018-0091-4 ↗
7. Eliaz, N. (2012). Biodegradable Metals. Degradation of Implant Materials, Springer.10.1007/978-1-4614-3942-4 ↗
8. Resorbable polymer fixation for craniomaxillofacial surgery: Development and engineering paradigms10.1097/00001665-200011060-00011 ↗
9. Current status and future direction of biodegraable metallic and polymeric vascular scaffolds for next-generation stents10.1016/j.actbio.2017.07.019 ↗
10. Zinc exhibits ideal physiological corrosion behavior for bioabsorbable stents10.1002/adma.201300226 ↗
11. Biodegradable metal stents: A focused review on materials and clinical studies10.1166/jbt.2014.1263 ↗
12. Progress of biodegradable metals10.1016/j.pnsc.2014.08.014 ↗
13. Comparative in vitro study on pure metals (Fe, Mn, Mg, Zn and W) as biodegradable metals10.1016/j.jmst.2013.03.019 ↗
14. The neurobiology of zinc in health and disease10.1038/nrn1671 ↗
15. Biodegradable metals10.1016/j.mser.2014.01.001 ↗
16. In vitro investigation of Fe30Mn6Si shape memory alloy as potential biodegradable metallic material10.1016/j.matlet.2010.10.068 ↗
17. Zinc Signaling
18. Zn-Mg and Zn-Cu alloys for stenting applications: From nanoscale mechanical characterization to in vitro degradation and biocompatibility
19. Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation10.1016/j.actbio.2011.05.008 ↗
20. Effects of Mg on microstructure and corrosion properties of Zn–Mg alloy10.1016/j.jallcom.2014.03.025 ↗
21. Baciu, E.R., Cimpoesu, R., Vitalariu, A., Baciu, C., Cimpoesu, N., Sodor, A., Zegan, G., and Murariu, A. (2021). Surface analysis of 3D (SLM) Co-Cr-W dental metallic materials. Appl. Sci., 11.10.3390/app11010255 ↗
22. Cimpoesu, R., Vizureanu, P., Stirbu, I., Sodor, A., Zegan, G., Prelipceanu, M., Cimpoesu, N., and Ioanid, N. (2021). Corrosion-Resistance Analysis of HA Layer Deposited through Electrophoresis on Ti4Al4Zr Metallic Substrate. Appl. Sci.-Basel, 11.10.3390/app11094198 ↗
23. Bejinariu, C., Burduhos-Nergis, D.P., and Cimpoesu, N. (2021). Immersion Behavior of Carbon Steel, Phosphate Carbon Steel and Phosphate and Painted Carbon Steel in Saltwater. Materials, 14.10.3390/ma14010188 ↗
24. Cimpoesu, N., Sandulache, F., Istrate, B., Cimpoesu, R., and Zegan, G. (2018). Electrochemical Behavior of Biodegradable FeMnSi-MgCa Alloy. Metals, 8.10.3390/met8070541 ↗
25. Panaghie, C., Cimpoesu, R., Istrate, B., Cimpoesu, N., Bernevig, M.-A., Zegan, G., Roman, A.-M., Chelariu, R., and Sodor, A. (2021). New Zn3Mg-xY Alloys: Characteristics, Microstructural Evolution and Corrosion Behavior. Materials, 14.10.3390/ma14102505 ↗
26. The microstructure, stability, and elastic properties of 14H long-period stacking-ordered phase in Mg–Zn–Y alloys: A first-principles study10.1007/s10853-013-7755-1 ↗
27. Microstructures, mechanical properties and in vitro corrosion behavior of biodegradable Zn alloys microalloyed with Al, Mn, Cu, Ag and Li elements10.1016/j.jmst.2021.06.049 ↗
28. The influence of Ca and Cu additions on the microstructure, mechanical and degradation properties of Zn–Ca–Cu alloys for absorbable wound closure device applications
29. Microstructure, mechanical properties, in vitro degradation behavior and hemocompatibility of novel Zn–Mg–Sr alloys as biodegradable metals10.1016/j.matlet.2015.07.151 ↗
30. Structural and mechanical aspects of hypoeutectic Zn–Mg binary alloys for biodegradable vascular stent applications
31. Long-term in vitro corrosion behavior of Zn-3Ag and Zn-3Ag-0.5Mg alloys considered for biodegradable implant applications10.1016/j.matdes.2021.110289 ↗
32. Microstructure evolution and mechanical performance of ternary Zn-0.8Mg-0.2Sr (wt. %) alloy processed by equal-channel angular pressing10.1016/j.msea.2021.141809 ↗
33. Microstructure, mechanical properties, and biodegradation response of the grain-refined Zn alloys for potential medical materials10.1016/j.jmrt.2021.08.024 ↗
34. Benefits of use of acoustic emission in scratch testing
35. Gallego, A., Piotrkowski, R., Ruzzante, J., Cabo, A., Garcia-Hernandez, M.T., and Castro, E. (2021, October 24). Acoustic Emission Technique to Assess Microfractures of Metallic Coatings with Scratch-Tests. PACS Reference: 43.35.Zc. 8. Available online: http://sea-acustica.es/fileadmin/publicaciones/Sevilla02_ult03012.pdf.
36. Influence of thermal treatment on microstructure, mechanical and degradation properties of Zn–3Mg alloy as potential biodegradable implant material10.1016/j.matdes.2015.06.181 ↗
37. Song, J. (2019). Theory of Diffusion Impedance in Nanostructured Electrochemical Systems. [Ph.D. Thesis, Massachusetts Institute of Technology].
38. Mathematical modeling of porous battery electrodes—Revisit of Newman’s model10.1016/j.electacta.2011.01.012 ↗
39. Roman, A.M., Geantă, V., Cimpoesu, R., Munteanu, C., Lohan, N.M., Zegan, G., Cernei, E.R., Ionită, I., Cimpoesu, N., and Ioanid, N. (2022). In-Vitro Analysis of FeMn-Si Smart Biodegradable Alloy. Materials, 15.10.3390/ma15020568 ↗