journal article·2021-09-08Open access

Oral Manifestations in Scurvy Pediatric Patients: A Systematic Review and a Case Report

Maria Francesca Gicchino, Antonio Romano, Speranza Cioffi, Fausto Fiori, Emanuele Miraglia del Giudice, Alberta Lucchese, Alma Nunzia Olivieri, Rosario Serpico

Applied Sciences· Volume 11· Issue 18

Abstract

Scurvy is generated by lack of vitamin C; although it is considered a rare and past disease, scurvy continues to be detected in children with neurodevelopmental disorders and with selective diet habits. Identifying scurvy can be demanding due to the perceived rarity of the condition, and it can become a tricky diagnostic question given to the variety of nonspecific symptoms, including gingival manifestations. This study aims to identify most common clinical features in order to provide a complete picture of the signs and symptoms, and to offer clinicians the diagnostic tools for identifying patients suffering from scurvy. We present a case report of a child affected by scurvy; it has also been performed as a systematic review about scurvy in pediatric population. A search yielded 107 relevant studies since 1990. Most of the identified cases have shown oral, musculoskeletal and cutaneous manifestation that improved within a few days of starting vitamin C therapy. Identifying scurvy’s characteristic clinical features allows a timely diagnosis, thus avoiding invasive investigations. Pediatric dentists should possess adequate knowledge and experience to identify the main characteristics of scurvy. This can help facilitate a prompt diagnosis in order to provide timely intervention to the patient that is relatively ease and safe.
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Research context

OpenAlex topics: Vitamin C and Antioxidants Research · Vitamin K Research Studies · Alcoholism and Thiamine Deficiency

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Woman and Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, via De Crecchio 6, 80138 Naples, Italy

Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, via De Crecchio 6, 80138 Naples, Italy

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