Advanced Biological Imaging for Intracellular Micromanipulation: Methods and Applications
Source abstract
Abstract
Intracellular micromanipulation assisted by robotic systems has valuable applications in biomedical research, such as genetic diagnosis and genome-editing tasks. However, current studies suffer from a low success rate and a large operation damage because of insufficient information on the operation information of targeted specimens. The complexity of the intracellular environment causes difficulties in visualizing manipulation tools and specimens. This review summarizes and analyzes the current development of advanced biological imaging sampling and computational processing methods in intracellular micromanipulation applications. It also discusses the related limitations and future extension, providing an important reference about this field.
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Research context
OpenAlex topics: Cell Image Analysis Techniques · Advanced Fluorescence Microscopy Techniques · Microfluidic and Bio-sensing Technologies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
State Key Laboratory for Manufacturing Systems Engineering and the International Joint Laboratory for Micro/Nano Manufacturing and Measurement Technologies, School of Mechanical Engineering, Xi’an Jiaotong University, Xi’an 710049, China
Department of Biomedical Engineering, City University of Hong Kong, Hong Kong SAR 999077, China
Funding
Research Grants Council, University Grants Committee · National Natural Science Foundation of China · 111 Program
References (100+)
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