Potential Applications of Clay-Based Therapy for the Reduction of Pesticide Exposures in Humans and Animals
Source abstract
Abstract
The risk of pesticide exposure in humans and animals may be magnified following natural and man-made disasters such as hurricanes and floods that can result in mobilization and redistribution of contaminated sediments. To develop broad-acting sorbents for mixtures of diverse toxins, we have processed calcium and sodium montmorillonite clays with high concentrations of sulfuric acid. These acid-processed montmorillonite clays (APMs) have shown limited hydration and swelling in water, higher surface areas, and lower trace metal levels than the parent clays, prior to processing. Isothermal analyses have indicated that newly developed APMs are highly active sorbents, with significantly increased binding capacities for a wide range of pesticides, including pentachlorophenol (PCP), 2,4,6-trichlorophenol (2,4,6-TCP), lindane, diazinon, linuron, trifluralin and paraquat. The safety and protective effects of APMs, against pesticide design mixtures, were confirmed in a living organism (Hydra vulgaris). Further work is planned to confirm the safety of the APMs in long-term rodent studies. This is the first report of a sorbent material (other than carbon) with high binding efficacy for mixtures of these pesticides. Based on our results, APMs (and similar clays), may be able to decrease human and animal pesticide exposures during disasters and emergencies.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Pesticide Exposure and Toxicity · Pesticide and Herbicide Environmental Studies · Vitamin C and Antioxidants Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Veterinary Integrative Biosciences Department, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA
Funding
National Institute of Environmental Health Sciences · U.S. Department of Agriculture
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