journal article·2024-05-21Open access

Improving Anorexia Nervosa Treatment with Virtual Reality Body Exposure and Attentional Bias Modification: A Single Case Study

Mariarca Ascione, Eduardo Serrano-Troncoso, Marta Carulla-Roig, Anna Blasco Martínez, Fernando Guerrero Álvarez, Franck-Alexandre Meschberger-Annweiler, Bruno Porras-Garcia, Marta Ferrer-Garcia, José Gutierrez-Maldonado

Applied Sciences· Volume 14· Issue 11

Abstract

This case study explores the potential of integrating attentional bias modification training (ABMT) with mirror exposure therapy (MET), utilizing virtual reality and eye-tracking, for a 14-year-old girl diagnosed with anorexia nervosa (AN). The ABMT-MET intervention was used alongside a standard treatment program called Home Treatment (HoT), which combines cognitive behavioral therapy with family-based therapy. Though the patient began HoT with a 3-week inpatient phase, the ABMT-MET intervention specifically took place during the subsequent Home Treatment sessions. The experimental treatment, comprising five consecutive weekly sessions, was bookended by pre- and post-assessment sessions and included a six-month follow-up. During the sessions, the patient engaged in systematic and hierarchical exposure to a virtual representation of her silhouette, with gradual adjustments made to the avatar’s body mass index (BMI) toward a healthier range. ABMT sessions, conducted before each MET session, aimed to redistribute the patient’s focus evenly across her body, successfully neutralizing her initial attentional bias toward non-weight-related body parts. The patient demonstrated consistent decreases in anxiety and fear of weight gain, effectively progressing through the BMI hierarchy in the virtual setting. Post-treatment assessments indicated significant enhancements in body dissatisfaction, drive for thinness, body-checking behaviors, and body appreciation, with these gains preserved at the six-month follow-up, although the attentional bias returned to pre-treatment levels. Though the single-case design limits definitive conclusions, these findings suggest ABMT-MET may be a promising adjunct therapy for AN, requiring further research for confirmation.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Eating Disorders and Behaviors · Virtual Reality Applications and Impacts · Impact of Technology on Adolescents

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Clinical Psychology and Psychobiology, University of Barcelona, Passeig de la Vall d’Hebron 171, 08035 Barcelona, Spain

Institute of Neurosciences, University of Barcelona, Passeig de la Vall d’Hebron 171, 08035 Barcelona, Spain

Department of Child and Adolescent Mental Health, Hospital Sant Joan de Déu, Passeig Sant Joan de Déu, 2, 08950 Barcelona, Spain

Child and Adolescent Mental Health Research Group, Institut de Recerca Sant Joan de Déu, Santa Rosa 39-57, 08950 Barcelona, Spain

Department of Basic Sciences, Universitat Internacional de Catalunya, Josep Trueta Street, s/n, 08195 Barcelona, Spain

Funding

Spanish Ministry of Science and Innovation (Agencia Estatal de In-vestigación, Ministerio de Ciencia e Innovación, Spain) · Fundació La Marató de TV3

References (56)

Show source-provided references
1. Incidence, prevalence and mortality of anorexia nervosa and bulimia nervosa10.1097/YCO.0000000000000739 ↗
2. Mirror exposure therapy for body image disturbances and eating disorders: A review10.1016/j.cpr.2018.08.006 ↗
3. Body image treatment within an inpatient program for anorexia nervosa: The role of mirror exposure in the desensitization process10.1002/eat.10027 ↗
4. Adjunctive mirror exposure for eating disorders: A randomized controlled pilot study10.1016/j.brat.2012.09.004 ↗
5. Mirror exposure to increase body satisfaction: Should we guide the focus of attention towards positively or negatively evaluated body parts?10.1016/j.jbtep.2015.06.002 ↗
6. Porras-Garcia, B., Ferrer-Garcia, M., Serrano-Troncoso, E., Carulla-Roig, M., Soto-Usera, P., Miquel-Nabau, H., Olivares, L.F.C., Marnet-Fiol, R., Santos-Carrasco, I.M., and Borszewski, B. (2021). AN-VR-BE. A Randomized Controlled Trial for Reducing Fear of Gaining Weight and Other Eating Disorder Symptoms in Anorexia Nervosa through Virtual Reality-Based Body Exposure. J. Clin. Med., 10.10.3390/jcm10040682 ↗
7. Addressing the fear of fat: Extending imaginal exposure therapy for anxiety disorders to anorexia nervosa10.1007/s40519-014-0115-6 ↗
8. Selective visual attention towards oneself and associated state body satisfaction: An eye-tracking study in adolescents with different types of eating disorders10.1007/s10802-017-0263-z ↗
9. Mendoza-Medialdea, M.T., Meschberger-Annweiler, F.A., Ascione, M., Rueda-Pina, A., Rabarbari, E., Porras-Garcia, B., Ferrer-Garcia, M., and Gutiérrez-Maldonado, J. (2023). Body Dissatisfaction and Body-Related Attentional Bias: Is There a Causal Relationship?. J. Clin. Med., 12.10.3390/jcm12175659 ↗
10. Cognitive-behavioral theories of eating disorders10.1177/0145445503259853 ↗
11. Information processing biases in eating disorders10.1016/j.cpr.2003.10.004 ↗
12. Attentional bias for body and food in eating disorders: Increased distraction, speeded detection, or both?10.1016/j.brat.2007.12.003 ↗
13. Selective Attention of Patients with Anorexia Nervosa While Looking at Pictures of Their Own Body and the Bodies of Others: An Exploratory Study10.1097/PSY.0b013e31823ba787 ↗
14. Selective visual attention for ugly and beautiful body parts in eating disorders10.1016/j.brat.2004.01.003 ↗
15. Tuschen-Caffier, B., Bender, C., Caffier, D., Klenner, K., Braks, K., and Svaldi, J. (2015). Selective visual attention during mirror exposure in anorexia and bulimia nervosa. PLoS ONE, 10.10.1371/journal.pone.0145886 ↗
16. The way we look at our own body really matters! Body-related attentional bias as a predictor of worse clinical outcomes after a virtual reality body exposure therapy
17. Attention bias modification: A new approach to the treatment of eating disorders?10.1002/eat.22107 ↗
18. Does attention bias modification improve attentional control? A double-blind randomized experiment with individuals with social anxiety disorder10.1016/j.janxdis.2014.10.007 ↗
19. Attention bias modification for reducing speech anxiety10.1016/j.brat.2013.10.001 ↗
20. Visual search attentional bias modification reduced social phobia in adolescents10.1016/j.jbtep.2013.11.006 ↗
21. A preliminary evaluation of a home-based, computer-delivered attention training treatment for anxious children living in regional communities10.5127/jep.053315 ↗
22. Meschberger-Annweiler, F.A., Ascione, M., Porras-Garcia, B., Ferrer-Garcia, M., Moreno-Sanchez, M., Miquel-Nabau, H., Serrano-Troncoso, E., Carulla-Roig, M., and Gutiérrez-Maldonado, J. (2023). An Attentional Bias Modification Task, through Virtual Reality and Eye-Tracking Technologies, to Enhance the Treatment of Anorexia Nervosa. J. Clin. Med., 12.10.3390/jcm12062185 ↗
23. Miquel-Nabau, H., Briseño-Oloriz, N., Porras-Garcia, B., Ascione, M., Meschberger-Annweiler, F.A., Ferrer-Garcia, M., Moreno-Sanchez, M., Serrano-Troncoso, E., Carulla-Roig, M., and Gutiérrez Maldonado, J. (2023). Modification of Body-Related Attentional Bias through Virtual Reality and Eye-Tracking in Healthy Participants: Implications for Anorexia Nervosa Treatments. Brain Sci., 13.10.3390/brainsci13050764 ↗
24. Ascione, M., Carulla-Roig, M., Miquel-Nabau, H., Porras-Garcia, B., Meschberger-Annweiler, F.A., Serrano-Troncoso, E., Ferrer-Garcia, M., Moreno-Sánchez, M., and Gutierrez-Maldonado, J. (2023). Attentional Bias Modification Training Based on Virtual Reality and Eye Tracking in Anorexia Nervosa Patients. J. Clin. Med., 12.10.3390/jcm12185932 ↗
25. Eye tracking of attention in the affective disorders: A meta-analytic review and synthesis10.1016/j.cpr.2012.09.004 ↗
26. Testing virtual reality-based cue-exposure software: Which cue-elicited responses best discriminate between patients with eating disorders and healthy controls?
27. Agras, W.S., and Robinson, A.H. (2018). The Oxford Handbook of Eating Disorders, Oxford University Press. [2nd ed.].10.1093/oxfordhb/9780190620998.001.0001 ↗
28. Virtual reality body swapping: A tool for modifying the allocentric memory of the body10.1089/cyber.2015.0229 ↗
29. Does owning a “fatter” virtual body increase body anxiety in college students?
30. Porras Garcia, B., Ferrer Garcia, M., Olszewska, A., Yilmaz, L., González Ibañez, C., Gracia Blanes, M., Gültekin, G., Serrano Troncoso, E., and Gutiérrez Maldonado, J. (2019). Is this my own body? changing the perceptual and affective body image experience among college students using a new virtual reality embodiment-based technique. J. Clin. Med., 8.10.3390/jcm8070925 ↗
31. American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Association Publishing. [5th ed.].10.1176/appi.books.9780890425596 ↗
32. ‘Therapists in action’-Home treatment in adolescent anorexia nervosa: A stepped care approach to shorten inpatient treatment10.1002/erv.2755 ↗
33. A substantive and methodological review of family-based treatment for eating disorders: The last 25 years of research: Eating disorder treatment10.1111/j.1467-6427.2011.00566.x ↗
34. Effectiveness of psychological interventions for eating disorders in adolescence: An overview of systematic reviews
35. The five tenets of family-based treatment for adolescent eating disorders10.1186/s40337-022-00585-y ↗
36. Hyönä, J., Radach, R., and Deubel, H. (2003). The Mind’s Eye: Cognitive and Applied Aspects of Eye Movement Research, Elsevier.
37. Development and validation of the Physical Appearance State and Trait Anxiety Scale (PASTAS)10.1016/0887-6185(91)90032-O ↗
38. A review of existing measures of attentional biases in body image and eating disorders research: Attentional measures in body image research10.1111/ajpy.12161 ↗
39. Eye-tracking research in eating disorders: A systematic review
40. Garner, D.M. (2004). Eating Disorder Inventory-3. Professional Manual, Psychological Assessment Resources.
41. Elosua, P., López-Jaúregui, A., and Sánchez-Sánchez, F. (2010). EDI-3, Inventario de Trastornos de la Conducta Alimentaria-3, Manual, Tea Ediciones.
42. Development of the body checking questionnaire: A self-report measure of body checking behaviors10.1002/eat.10012 ↗
43. The Body Appreciation Scale: Development and psychometric evaluation10.1016/j.bodyim.2005.06.002 ↗
44. Spanish version of the Body Appreciation Scale (BAS) for adolescents10.5209/rev_SJOP.2011.v14.n1.37 ↗
45. SUS—A quick and dirty usability scale
46. Porras-Garcia, B., Ferrer-Garcia, M., Serrano-Troncoso, E., Carulla-Roig, M., Soto-Usera, P., Miquel-Nabau, H., Shojaeian, N., de la Montaña Santos-Carrasco, I., Borszewski, B., and Díaz-Marsá, M. (2020). Validity of virtual reality body exposure to elicit fear of gaining weight, body anxiety and body-related attentional bias in patients with anorexia nervosa. J. Clin. Med., 9.10.3390/jcm9103210 ↗
47. Looking good. BMI, attractiveness bias and visual attention10.1016/j.appet.2008.04.008 ↗
48. World Health Organization [WHO] (2004). International Statistical Classification of Diseases and Related Health Problems, Tenth Revision.
49. Bias for the (un)attractive self: On the role of attention in causing body (dis)satisfaction10.1037/a0022095 ↗
50. Clinical significance: A statistical approach to defining meaningful change in psychotherapy research10.1037/0022-006X.59.1.12 ↗
51. Morley, S., and Dowzer, C.N. (2014). Manual for the Leeds Reliable Change Indicator: Simple Excel(tm) Applications for the Analysis of Individual Patient and Group Data, University of Leeds.
52. The Time Course of Attentional Allocation While Women High and Low in Body Dissatisfaction View Self and Model Physiques10.1080/08870440701697367 ↗
53. Virtual reality in the treatment of generalized anxiety disorders
54. Take a look at the bright side: Effects of positive body exposure on selective visual attention in women with high body dissatisfaction10.1016/j.brat.2016.05.006 ↗
55. Magrini, M., Curzio, O., Tampucci, M., Donzelli, G., Cori, L., Imiotti, M.C., Maestro, S., and Moroni, D. (2022). Anorexia Nervosa, Body Image Perception and Virtual Reality Therapeutic Applications: State of the Art and Operational Proposal. Int. J. Environ. Res. Public Health, 19.10.3390/ijerph19052533 ↗
56. Matamala-Gomez, M., Maselli, A., Malighetti, C., Realdon, O., Mantovani, F., and Riva, G. (2021). Virtual Body Ownership Illusions for Mental Health: A Narrative Review. J. Clin. Med., 10.10.3390/jcm10010139 ↗