journal article·2025-02-07Open access

Assessing Cardiac Sympatho-Vagal Balance Through Wavelet Transform Analysis of Heart Rate Variability

A.M. Nelushi, C.H. Manathunga, N.G.S. Shantha Gamage, Tadachika Nakayama

Applied Sciences· Volume 15· Issue 4

Abstract

Heart rate variability (HRV), which is the variation between consecutive heartbeats, reflects the electrical activity of the heart and provides insight into the autonomic nervous system (ANS) function. This study uses wavelet transform-based HRV feature extraction to investigate cardiac sympatho-vagal balance. Both the continuous wavelet transform (CWT) and discrete wavelet transform (DWT) methods were applied in different steps. DWT was used for R-peak detection and CWT and MODWT were used to generate spectrograms from RR intervals. Frequency components (HF, LF, and VLF) within 0.003–0.4 Hz were extracted, and power estimation was performed. The LF/HF ratio, indicating sympatho-vagal balance, was calculated. ECG data from 42 arrhythmia patients and 18 normal sinus rhythm subjects were analyzed. The results showed a lower LF/HF ratio in arrhythmia patients, with higher HF power in arrhythmia subjects and higher LF power in normal sinus rhythm subjects. The study suggests that the parasympathetic nervous system dominates the ANS in arrhythmia patients, while the sympathetic nervous system dominates in normal sinus rhythm patients.
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Research context

OpenAlex topics: Heart Rate Variability and Autonomic Control · Non-Invasive Vital Sign Monitoring · ECG Monitoring and Analysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Physics, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka

Department of Science and Technology Innovation, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka 940-2188, Niigata, Japan

Extreme Energy–Density Research Institute (EDI), Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka 940-2188, Niigata, Japan

References (47)

Show source-provided references
1. Heart rate variability: Origins, methods, and interpretive caveats10.1111/j.1469-8986.1997.tb02140.x ↗
2. Stress and heart rate variability: A meta-analysis and review of the literature10.30773/pi.2017.08.17 ↗
3. Electronic evaluations of the fetal heart rate patterns preceding fetal death: Further observations
4. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction10.1016/0002-9149(87)90795-8 ↗
5. Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study10.1161/01.CIR.90.2.878 ↗
6. The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors10.1016/j.ijcard.2009.09.543 ↗
7. Depression, heart rate variability, and acute myocardial infarction10.1161/hc4201.097834 ↗
8. Heart rate variability in depressive and anxiety disorders10.1067/mhj.2000.109981 ↗
9. Chalmers, J.A., Quintana, D.S., Abbott, M.J.-A., and Kemp, A.H. (2014). Anxiety disorders are associated with reduced heart rate variability: A meta-analysis. Front. Psychiatry, 5.10.3389/fpsyt.2014.00080 ↗
10. Influence of age and gender on autonomic regulation of heart10.1007/s10877-012-9424-3 ↗
11. Methods derived from nonlinear dynamics for analysing heart rate variability10.1098/rsta.2008.0232 ↗
12. Standardized tests of heart rate variability: Normal ranges obtained from 309 healthy humans, and effects of age, gender, and heart rate10.1007/BF02322053 ↗
13. Twenty-Four Hour Time Domain Heart Rate Variability and Heart Rate: Relations to Age and Gender Over Nine Decades10.1016/S0735-1097(97)00554-8 ↗
14. Effects of Gender and Aging on Differential Autonomic Responses to Orthostatic Maneuvers10.1111/j.1540-8167.2008.01257.x ↗
15. Effects of active and passive tobacco cigarette smoking on heart rate variability10.1016/j.ijcard.2011.10.140 ↗
16. Heart rate variability in alcohol use: A review10.1016/j.pbb.2018.12.003 ↗
17. The effects of exposure to environmental factors on Heart Rate Variability: An ecological perspective10.1016/j.envpol.2013.02.005 ↗
18. Time-frequency analysis of heart rate variability using short-time Fourier analysis10.1088/0967-3334/21/2/303 ↗
19. Heart rate variability: A review10.1007/s11517-006-0119-0 ↗
20. Boashash, B. (2015). Time-Frequency Signal Analysis and Processing: A Comprehensive Reference, Academic Press.
21. Daubechies, I. (1992). Ten Lectures on Wavelets, SIAM.10.1137/1.9781611970104 ↗
22. QRS detection using new wavelets10.1080/03091900110096038 ↗
23. Comparative study of QRS complex detection in ECG
24. A Robust R Peak Detection Algorithm Using Wavelet Transform for Heart Rate Variability Studies
25. Detection of ECG characteristic points using wavelet transforms10.1109/10.362922 ↗
26. A Real-Time QRS Detector Based on Discrete Wavelet Transform and Cubic Spline Interpolation10.1089/tmj.2008.0073 ↗
27. A theory for multiresolution signal decomposition: The wavelet representation10.1109/34.192463 ↗
28. A discrete-time multiresolution theory10.1109/78.229891 ↗
29. Pale, U., Thürk, F., and Kaniusas, E. (June, January 30). Heart rate variability analysis using different wavelet transformations. Proceedings of the 2016 39th International Convention on Information and Communication Technology, Electronics and Microelectronics (MIPRO), Opatija, Croatia.10.1109/MIPRO.2016.7522403 ↗
30. Computer-aided diagnosis of diabetic subjects by heart rate variability signals using discrete wavelet transform method10.1016/j.knosys.2015.02.005 ↗
31. Comparison of Wavelet Types and Thresholding Methods on Wavelet Based Denoising of Heart Sounds
32. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals10.1161/01.CIR.101.23.e215 ↗
33. The impact of the MIT-BIH Arrhythmia Database10.1109/51.932724 ↗
34. Elgendi, M., Jonkman, M., and De Boer, F. (2010). Frequency Bands Effects on QRS Detection. Biosignals, 2003.
35. Cartas-Rosado, R., Becerra-Luna, B., Martínez-Memije, R., Infante-Vázquez, Ó., Lerma, C., Pérez-Grovas, H., and Rodríguez-Chagolla, J.M. (2020). Continuous wavelet transform based processing for estimating the power spectrum content of heart rate variability during hemodiafiltration. Biomed. Signal Process. Control, 62.10.1016/j.bspc.2020.102031 ↗
36. Heart rate variability: Standards of measurement, physiological interpretation, and clinical use10.1093/oxfordjournals.eurheartj.a014868 ↗
37. Dar, M.N., Akram, M.U., Usman, A., and Khan, S.A. (2015, January 15–17). ECG biometric identification for general population using multiresolution analysis of DWT based features. Proceedings of the 2015 Second International Conference on Information Security and Cyber Forensics (InfoSec), Cape Town, South Africa.10.1109/InfoSec.2015.7435498 ↗
38. Hernando, A., Posada-Quintero, H., Peláez-Coca, M.D., Gil, E., and Chon, K.H. (2022). Autonomic Nervous System characterization in hyperbaric environments considering respiratory component and non-linear analysis of Heart Rate Variability. Comput. Methods Programs Biomed., 214.10.1016/j.cmpb.2021.106527 ↗
39. Assessment of autonomic function in humans by heart rate spectral analysis10.1152/ajpheart.1985.248.1.H151 ↗
40. Beat to beat variability in cardiovascular variables: Noise or music?10.1016/0735-1097(89)90408-7 ↗
41. Cardiovascular neural regulation explored in the frequency domain10.1161/01.CIR.84.2.482 ↗
42. Power spectrum analysis of heart rate variability to assess the changes in sympathovagal balance during graded orthostatic tilt10.1161/01.CIR.90.4.1826 ↗
43. The US Preventive Services Task Force Guide to Clinical Preventive Services, AMA Council on Scientific Affairs
44. Heart rate variability: A noninvasive electrocardiographic method to measure the autonomic nervous system
45. Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog10.1161/01.RES.59.2.178 ↗
46. Wavelet Transform based HRV Analysis10.1016/j.protcy.2013.12.462 ↗
47. Shaffer, F., and Ginsberg, J.P. (2017). An Overview of Heart Rate Variability Metrics and Norms. Front. Public Health, 5.10.3389/fpubh.2017.00258 ↗