Early Oral Cancer Detection with AI: Design and Implementation of a Deep Learning Image-Based Chatbot

Oral cancer remains a critical global health challenge, with delayed diagnosis driving high morbidity and mortality. Despite progress in artificial intelligence, computer vision, and medical imaging, early detection tools that are accessible, explainable, and designed for patient engagement remain limited. This study presents a novel system that combines a patient-centred chatbot with a deep learning framework to support early diagnosis, symptom triage, and health education. The system integrates convolutional neural networks, class activation mapping, and natural language processing within a conversational interface. Five deep learning models were evaluated (CNN, DenseNet121, DenseNet169, DenseNet201, and InceptionV3) using two balanced public datasets. Model performance was assessed using accuracy, sensitivity, specificity, diagnostic odds ratio (DOR), and Cohen’s Kappa. InceptionV3 consistently outperformed the other models across these metrics, achieving the highest diagnostic accuracy (77.6%) and DOR (20.67), and was selected as the core engine of the chatbot’s diagnostic module. The deployed chatbot provides real-time image assessments and personalised conversational support via multilingual web and mobile platforms. By combining automated image interpretation with interactive guidance, the system promotes timely consultation and informed decision-making. It offers a prototype for a chatbot, which is scalable and serves as a low-cost solution for underserved populations and demonstrates strong potential for integration into digital health pathways. Importantly, the system is not intended to function as a formal screening tool or replace clinical diagnosis; rather, it provides preliminary guidance to encourage early medical consultation and informed health decisions.