A Non-Invasive Fetal QRS Complex Detection Method Based on a Multi-Feature Fusion Neural Network
Source abstract
Abstract
Fetal heart monitoring, as a crucial part of fetal monitoring, can accurately reflect the fetus’s health status in a timely manner. To address the issues of high computational cost, inability to observe fetal heart morphology, and insufficient accuracy associated with the traditional method of calculating the fetal heart rate using a four-channel maternal electrocardiogram (ECG), a method for extracting fetal QRS complexes from a single-channel non-invasive fetal ECG based on a multi-feature fusion neural network is proposed. Firstly, a signal entropy data quality detection algorithm based on the blind source separation method is designed to select maternal ECG signals that meet the quality requirements from all channel ECG data, followed by data preprocessing operations such as denoising and normalization on the signals. After being segmented by the sliding window method, the maternal ECG signals are calculated as data in four modes: time domain, frequency domain, time–frequency domain, and data eigenvalues. Finally, the deep neural network using three multi-feature fusion strategies—feature-level fusion, decision-level fusion, and model-level fusion—achieves the effect of quickly identifying fetal QRS complexes. Among the proposed networks, the one with the best performance has an accuracy of 95.85% and sensitivity of 97%.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: ECG Monitoring and Analysis · Blind Source Separation Techniques · Neonatal and fetal brain pathology
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Electronic Engineering, Beijing University of Posts and Telecommunications, Beijing 100876, China
Technical Department, Beijing Health State Monitoring & Consulting Co., Ltd., Beijing 100080, China
References (51)
Show source-provided references
1. Continuous Cardiotocography (CTG) as a Form of Electronic Fetal Monitoring (EFM) for Fetal Assessment during Labour
2. Anisha, M., Kumar, S.S., Nithila, E.E., and Benisha, M. (2021). Detection of Fetal Cardiac Anomaly from Composite Abdominal Electrocardiogram. Biomed. Signal Process. Control, 65.10.1016/j.bspc.2020.102308 ↗
3. Doppler Ultrasound Technology for Fetal Heart Rate Monitoring: A Review10.1109/TUFFC.2019.2943626 ↗
4. Remote Plethysmographic Imaging Using Ambient Light10.1364/OE.16.021434 ↗
5. Varanini, M., Tartarisco, G., Billeci, L., Macerata, A., Pioggia, G., and Balocchi, R. (2013, January 22–25). A Multi-Step Approach for Non-Invasive Fetal ECG Analysis. Proceedings of the Computing in Cardiology 2013, Zaragoza, Spain.
6. Extracting Fetal Heart Signal from Noisy Maternal ECG by Multivariate Singular Spectrum Analysis10.4310/SII.2010.v3.n3.a12 ↗
7. An Efficient Unsupervised Fetal QRS Complex Detection from Abdominal Maternal ECG10.1088/0967-3334/35/8/1607 ↗
8. Power-MF: Robust Fetal QRS Detection from Non-Invasive Fetal Electrocardiogram Recordings10.1088/1361-6579/ad4952 ↗
9. A Novel Deep Learning Technique for Morphology Preserved Fetal ECG Extraction from Mother ECG Using 1D-CycleGAN10.1016/j.eswa.2023.121196 ↗
10. Single-Lead Noninvasive Fetal ECG Extraction by Means of Combining Clustering and Principal Components Analysis10.1007/s11517-019-02087-7 ↗
11. An Effective Integrated Framework for Fetal QRS Complex Detection Based on Abdominal ECG Signal10.1007/s40846-024-00850-2 ↗
12. Kahankova, R., Mikolasova, M., and Martinek, R. (2022). Optimization of Adaptive Filter Control Parameters for Non-Invasive Fetal Electrocardiogram Extraction. PLoS ONE, 17.10.1371/journal.pone.0266807 ↗
13. Fetal QRS Extraction from Single-Channel Abdominal ECG Using Adaptive Improved Permutation Entropy10.1007/s13246-024-01386-0 ↗
14. Petrolis, R., and Krisciukaitis, A. (2013, January 22–25). Multi Stage Principal Component Analysis Based Method for Detection of Fetal Heart Beats in Abdominal ECGs. Proceedings of the Computing in Cardiology 2013, Zaragoza, Spain.
15. Deogire, A.D. (2018, January 6–8). Multi Lead Fetal QRS Detection with Principal Component Analysis. Proceedings of the 2018 3rd International Conference for Convergence in Technology (I2CT), Pune, India.10.1109/I2CT.2018.8529322 ↗
16. Evaluation of an Improved Algorithm for Fetal QRS Detection
17. Niknazar, M., Rivet, B., and Jutten, C. (2013, January 22–25). Fetal QRS Complex Detection Based on Three-Way Tensor Decomposition. Proceedings of the Computing in Cardiology 2013, Zaragoza, Spain.
18. Perlman, O., Katz, A., and Zigel, Y. (2013, January 22–25). Noninvasive Fetal QRS Detection Using a Linear Combination of Abdomen ECG Signals. Proceedings of the Computing in Cardiology 2013, Zaragoza, Spain.
19. A Dual Attention-Based Autoencoder Model for Fetal ECG Extraction From Abdominal Signals10.1109/JSEN.2022.3213586 ↗
20. Sharma, K., and Masood, S. (2021). Deep Learning-Based Non-Invasive Fetal Cardiac Arrhythmia Detection. Applications of Artificial Intelligence and Machine Learning, Springer.10.1007/978-981-16-3067-5_38 ↗
21. Fetal QRS Complexes Detection Using Deep Learning Technique10.1007/s42835-023-01682-x ↗
22. Nguyen, V.D. (2024, January 17–21). Fetal ECG Extraction on Time-Frequency Domain Using Conditional GAN. Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, Seattle, WA, USA.10.1109/CVPRW63382.2024.00499 ↗
23. A Deep Learning Approach for Fetal QRS Complex Detection10.1088/1361-6579/aab297 ↗
24. Lee, J.S., Seo, M., Kim, S.W., and Choi, M. (2018, January 24–27). Fetal QRS Detection Based on Convolutional Neural Networks in Noninvasive Fetal Electrocardiogram. Proceedings of the 2018 4th International Conference on Frontiers of Signal Processing (ICFSP), Poitiers, France.10.1109/ICFSP.2018.8552074 ↗
25. Vo, K., Le, T., Rahmani, A.M., Dutt, N., and Cao, H. (2020). An Efficient and Robust Deep Learning Method with 1-D Octave Convolution to Extract Fetal Electrocardiogram. Sensors, 20.10.3390/s20133757 ↗
26. PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals10.1161/01.CIR.101.23.e215 ↗
27. Non-Invasive Fetal ECG Analysis10.1088/0967-3334/35/8/1521 ↗
28. A Practical Guide to Non-Invasive Foetal Electrocardiogram Extraction and Analysis10.1088/0967-3334/37/5/R1 ↗
29. Determination of Fetal Heart Rate from Abdominal Signals: Evaluation of Beat-to-Beat Accuracy in Relation to the Direct Fetal Electrocardiogram
30. Physiological Time-Series Analysis Using Approximate Entropy and Sample Entropy10.1152/ajpheart.2000.278.6.H2039 ↗
31. A Multi-Step Method with Signal Quality Assessment and Fine-Tuning Procedure to Locate Maternal and Fetal QRS Complexes from Abdominal ECG Recordings10.1088/0967-3334/35/8/1665 ↗
32. A Comparison of the Denoising Performance Using Capon Time-Frequency and Empirical Wavelet Transform Applied on Biomedical Signal
33. Fetal ECG Extraction From Maternal ECG Using Attention-Based CycleGAN10.1109/JBHI.2021.3111873 ↗
34. A Dilated Inception CNN-LSTM Network for Fetal Heart Rate Estimation10.1088/1361-6579/abf7db ↗
35. Accurate Fetal QRS-Complex Classification from Abdominal Electrocardiogram Using Deep Learning10.1007/s44196-023-00339-x ↗
36. An Automated Methodology for Fetal Heart Rate Extraction From the Abdominal Electrocardiogram10.1109/TITB.2006.888698 ↗
37. Krishna, B.T. (2017, January 26–29). Fetal ECG Extraction Using Time-Frequency Analysis Techniques. Proceedings of the 2017 International Conference on Robotics and Automation Sciences (ICRAS), Hong Kong, China.10.1109/ICRAS.2017.8071938 ↗
38. Implementation for Fetal ECG Detection from Multi-Channel Abdominal Recordings with 2D Convolutional Neural Network10.1007/s11265-021-01676-w ↗
39. Non-Linear Methods in HRV Analysis10.1016/j.protcy.2016.01.134 ↗
40. Nonlinear Analysis of the Performance and Reliability of Wavelet Singularity Detection Based Denoising for Doppler Ultrasound Fetal Heart Rate Signals10.1016/S1386-5056(98)00102-6 ↗
41. Yan, J., Xia, C., Wang, H., Wang, Y., Guo, R., Li, F., and Yan, H. (2008, January 16–18). Nonlinear Dynamic Analysis of Wrist Pulse with Lyapunov Exponents. Proceedings of the 2008 2nd International Conference on Bioinformatics and Biomedical Engineering, Shanghai, China.10.1109/ICBBE.2008.874 ↗
42. Estimating Fractal Dimension10.1364/JOSAA.7.001055 ↗
43. Singular value decomposition tutorial
44. Huang, N.E. (2008). Hilbert-Huang Transform and Its Applications, World Scientific. Interdisciplinary Mathematical Sciences; Repr.
45. End-to-End Deep Learning Architecture for Separating Maternal and Fetal ECGs Using W-Net10.1109/ACCESS.2022.3166925 ↗
46. He, K., Zhang, X., Ren, S., and Sun, J. (2016, January 27–30). Deep Residual Learning for Image Recognition. Proceedings of the 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Las Vegas, NV, USA.10.1109/CVPR.2016.90 ↗
47. Vaswani, A., Shazeer, N., Parmar, N., Uszkoreit, J., Jones, L., Gomez, A.N., Kaiser, Ł., and Polosukhin, I. (2017). Attention Is All You Need. Proceedings of the Advances in Neural Information Processing Systems, Curran Associates, Inc.
48. Hori, C., Hori, T., Lee, T.-Y., Zhang, Z., Harsham, B., Hershey, J.R., Marks, T.K., and Sumi, K. (2017, January 22–29). Attention-Based Multimodal Fusion for Video Description. Proceedings of the 2017 IEEE International Conference on Computer Vision (ICCV), Venice, Italy.10.1109/ICCV.2017.450 ↗
49. Single Layer & Multi-Layer Long Short-Term Memory (LSTM) Model with Intermediate Variables for Weather Forecasting10.1016/j.procs.2018.08.153 ↗
50. Speech Emotion Recognition Using Deep 1D & 2D CNN LSTM Networks10.1016/j.bspc.2018.08.035 ↗
51. Zhang, X., Zhou, X., Lin, M., and Sun, J. (2018, January 18–23). ShuffleNet: An Extremely Efficient Convolutional Neural Network for Mobile Devices. Proceedings of the 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition, Salt Lake City, UT, USA.10.1109/CVPR.2018.00716 ↗