Comparative Metabolic Profiling of Different Raphanus sativus Cultivars and Their Antioxidant and Anti-Inflammatory Activities
Source abstract
Abstract
This study investigates the phytochemical composition of the aerial parts of three radish cultivars: KR 391, KR CheongHong, and KR 407, named RL1, RL2, and RL3, respectively, using UPLC–Orbitrap–MS to profile the secondary metabolites. The secondary metabolites were characterized to provide a comprehensive overview of their diversity and bioactivity. Multivariate analysis revealed cultivar-specific variations in metabolite profiles and tentatively identified 22 metabolites, which include 17 flavonoids and five phenolics. The extracts of the radish cultivars were tested for their cytotoxicity, antioxidant activity measured with a DPPH assay, and anti-inflammatory activity measured by NO production. The findings highlight the pharmaceutical potential of radish aerial parts and provide insights into the relationship between metabolite composition and biological activity, contributing to their value in health-promoting applications.
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Research context
OpenAlex topics: Phytochemicals and Antioxidant Activities · Phytochemistry and Biological Activities · Natural product bioactivities and synthesis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Integrative Biological Sciences and Industry, Sejong University, 209, Neungdong-ro, Gwangjin-gu, Seoul 05006, Republic of Korea
Agricultural Company Corporation DASANBIO Inc., 251-29, Ihwa-ro, Pyeongtaek-si 17865, Republic of Korea
Department of Bioresources Engineering, Sejong University, 209, Neungdong-ro, Gwangjin-gu, Seoul 05006, Republic of Korea
Funding
Research Program for Agricultural Science and Technology Development · Rural Development Administration · Ministry of Education
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