journal article·2025-03-24Open access

Development of Surrogate Model for Patient-Specific Lattice-Structured Hip Implant Design via Finite Element Analysis

Rashwan Alkentar, Tamás Mankovits

Applied Sciences· Volume 15· Issue 7

Abstract

Patient-tailored hip implants are a major area of development in orthopedic surgery. Thanks to the recent developments in titanium printing, the medical industry now places special demands on implants. The lattice design enhances osseointegration and brings the stiffness of the implant closer to that of the bone, so this is an important direction in the development of hip implant design processes. In our previous research, several lattice structures were compared from a strength perspective, considering surgical specifications regarding cell size. The so-called 3D lattice infill type built into ANSYS with a predefined size has proven to be suitable for medical practice and can be easily manufactured with additive manufacturing techniques. A major step in the implant design process is numerical strength analysis, which elucidates implant material response. Due to the complex geometry of the lattice structure, finite element calculations are extremely time-consuming and require high computation capacity; therefore, the focus of our current research was to develop a surrogate numerical model that provides sufficiently fast and accurate information about the behavior of the designed structure. The developed surrogate model reduces the simulation time by more than one hundred times, and the accuracy of the calculation is more than satisfactory for engineering practice. The deviation from the original model is, on average, below 5%, taking deformation into account. This makes the design phase much more manageable and competitive.
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Research context

OpenAlex topics: Orthopaedic implants and arthroplasty · Titanium Alloys Microstructure and Properties · Powder Metallurgy Techniques and Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Mechanical Engineering, Faculty of Engineering, University of Debrecen, Ótemető u. 2-4., H-4028 Debrecen, Hungary

Doctoral School of Informatics, Faculty of Informatics, University of Debrecen, Kassai u. 26., H-4028 Debrecen, Hungary

Funding

University of Debrecen Scientific Research Bridging Fund (DETKA) · OMAA 117öu9—Experimentelle und numerische Untersuchung maßgeschneiderter, zel-lulärer Implantate, hergestellt mit AM-Technologie project

References (43)

Show source-provided references
1. Prasad, K., Bazaka, O., Chua, M., Rochford, M., Fedrick, L., Spoor, J., Symes, R., Tieppo, M., Collins, C., and Cao, A. (2017). Metallic Biomaterials: Current Challenges and Opportunities. Materials, 10.10.3390/ma10080884 ↗
2. Park, J.O., and Bronzino, J.D. (2002). Biomaterials, Informa.10.1201/9781420040036 ↗
3. Metallic implant biomaterials10.1016/j.mser.2014.10.001 ↗
4. Highly porous, low elastic modulus 316L stainless steel scaffold prepared by selective laser melting10.1016/j.msec.2016.07.027 ↗
5. Kim, H.R., Jang, S.-H., Kim, Y.K., Son, J.S., Min, B.K., Kim, K.-H., and Kwon, T.-Y. (2016). Microstructures and Mechanical Properties of Co-Cr Dental Alloys Fabricated by Three CAD/CAM-Based Processing Techniques. Materials, 9.10.3390/ma9070596 ↗
6. Microstructure and mechanical properties of direct metal laser sintered TI-6AL-4V
7. Bari, K. (2023). Design, Simulation, and Mechanical Testing of 3D-Printed Titanium Lattice Structures. J. Compos. Sci., 7.10.3390/jcs7010032 ↗
8. Ti–6Al–4V triply periodic minimal surface structures for bone implants fabricated via selective laser melting10.1016/j.jmbbm.2015.06.024 ↗
9. The relationship between stress shielding and bone resorption around total Hip stems and the effects of flexible materials10.1097/00003086-199201000-00014 ↗
10. Effect of sintering conditions on the microstructural and mechanical characteristics of porous magnesium materials prepared by powder metallurgy10.1016/j.msec.2013.10.014 ↗
11. Microstructural and mechanical properties of biodegradable iron foam prepared by powder metallurgy10.1016/j.matdes.2015.06.022 ↗
12. CoCr porous scaffolds manufactured via selective laser melting in orthopedics: Topographical, mechanical, and biological characterization10.1002/jbm.b.34328 ↗
13. Porous titanium scaffolds fabricated using a rapid prototyping and powder metallurgy technique10.1016/j.biomaterials.2008.05.032 ↗
14. Surface Engineering for Bone Implants: A Trend from Passive to Active Surfaces10.3390/coatings2030095 ↗
15. Distefano, F., Pasta, S., and Epasto, G. (2023). Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review. J. Funct. Biomater., 14.10.3390/jfb14030125 ↗
16. Kladovasilakis, N., Tsongas, K., and Tzetzis, D. (2020). Finite Element Analysis of Orthopedic Hip Implant with Functionally Graded Bioinspired Lattice Structures. Biomimetics, 5.10.3390/biomimetics5030044 ↗
17. Nogueira, P., Lopes, P., Oliveira, L., Alves, J.L., Magrinho, J.P.G., de Deus, A.M., Vaz, M.F., and Silva, M.B. (2024). Evaluation of Lattice Structures for Medical Implants: A Study on the Mechanical Properties of Various Unit Cell Types. Metals, 14.10.3390/met14070780 ↗
18. Salaha, Z.F.M., Ammarullah, M.I., Abdullah, N.N.A.A., Aziz, A.U.A., Gan, H.-S., Abdullah, A.H., Kadir, M.R.A., and Ramlee, M.H. (2023). Biomechanical Effects of the Porous Structure of Gyroid and Voronoi Hip Implants: A Finite Element Analysis Using an Experimentally Validated Model. Materials, 16.10.3390/ma16093298 ↗
19. Chen, W., Zheng, X., and Liu, S. (2018). Finite-Element-Mesh Based Method for Modeling and Optimization of Lattice Structures for Additive Manufacturing. Materials, 11.10.3390/ma11112073 ↗
20. Design and analysis of strut-based lattice structures for vibration isolation10.1016/j.precisioneng.2017.09.010 ↗
21. Modelling and FE simulation of 3D printed Co-Cr Lattice Structures for biomedical applications10.1016/j.procir.2022.06.066 ↗
22. Numerical analysis of thermal damage by changing irradiation angle for peri-implantitis using photothermal therapy
23. Hoffer, J.G., Geiger, B.C., Ofner, P., and Kern, R. (2021). Mesh-Free Surrogate Models for Structural Mechanic FEM Simulation: A Comparative Study of Approaches. Appl. Sci., 11.10.3390/app11209411 ↗
24. The role of machine learning for insight into the material behavior of lattices: A surrogate model based on data from finite element simulation10.1016/j.rineng.2024.102547 ↗
25. Gongora, A.E., Friedman, C., Newton, D.K., Yee, T.D., Doorenbos, Z., Giera, B., Duoss, E.B., Han, T.Y.-J., Sullivan, K., and Rodriguez, J.N. (2024). Accelerating the design of lattice structures using machine learning. Sci. Rep., 14.10.1038/s41598-024-63204-7 ↗
26. Bai, J., Li, M., and Shen, J. (2024). Prediction of Mechanical Properties of Lattice Structures: An Application of Artificial Neural Networks Algorithms. Materials, 17.10.3390/ma17174222 ↗
27. High-resolution topology optimization method of multi-morphology lattice structures based on three-dimensional convolutional neural networks (3D-CNN)10.1007/s00158-023-03688-5 ↗
28. Bending behavior of 2D periodic plates with different unit cells: Numerical and experimental investigations10.1016/j.mtcomm.2022.103774 ↗
29. Analysis and optimization of strut-based lattice structures by simplified finite element method10.1007/s00707-022-03443-9 ↗
30. Müller, P., Synek, A., Stauß, T., Steinnagel, C., Ehlers, T., Gembarski, P.C., Pahr, D., and Lachmayer, R. (2024). Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE. Sci. Rep., 14.10.1038/s41598-024-56327-4 ↗
31. Closed-form effective elastic constants of frame-like periodic cellular solids by a symbolic object-oriented finite element program10.1007/s10999-016-9342-5 ↗
32. Effective out-of-plane rigidities of 2D lattices with different unit cell topologies10.1007/s00419-019-01547-8 ↗
33. Exact forms of effective elastic properties of frame-like periodic cellular solids10.1007/s00419-016-1129-5 ↗
34. In-Plane Stiffness and Yield Strength of Periodic Metal Honeycombs10.1115/1.1646165 ↗
35. Use of compression test to determine the Young’s modulus of the titanium alloy Ti6Al4V manufactured via direct metal laser sintering
36. Alkentar, R., Kladovasilakis, N., Tzetzis, D., and Mankovits, T. (2023). Effects of Pore Size Parameters of Titanium Additively Manufactured Lattice Structures on the Osseointegration Process in Orthopedic Applications: A Comprehensive Review. Crystals, 13.10.3390/cryst13010113 ↗
37. Alkentar, R., Máté, F., and Mankovits, T. (2022). Investigation of the Performance of Ti6Al4V Lattice Structures Designed for Biomedical Implants Using the Finite Element Method. Materials, 15.10.3390/ma15186335 ↗
38. (2011). Mechanical Testing of Metals—Ductility Testing—Compression Test for Porous and Cellular Metals (Standard No. ISO 13314:2011).
39. U.S Titanium Industry (2025, February 09). Titanium Alloys Ti6Al4V. Available online: https://www.azom.com/article.aspx?ArticleID=1547.
40. (2025, March 21). Standard Specification for Titanium and Titanium Alloy Bars and Billets. Available online: https://store.astm.org/standards/b348.
41. High-strength porous biomaterials for bone replacement: A strategy to assess the interplay between cell morphology, mechanical properties, bone ingrowth and manufacturing constraints10.1016/j.actbio.2015.10.048 ↗
42. (2010). Partial and Total Hip Joint Prostheses—Part 4: Determination of Endurance Properties and Performance of Stemmed Femoral Components 2010 (Standard No. ISO 7206-4:2010).
43. (2012). Standard Specification for Total Hip Joint Prosthesis and Hip Endoprosthesis Bearing Surfaces Made of Metallic, Ceramic, and Polymeric Materials (Standard No. ASTM F2033-12).