Recent Innovations Brought about by Weight-Bearing CT Imaging in the Foot and Ankle: A Systematic Review of the Literature
Source abstract
Abstract
The decade from 2010–2020 has seen the development of cone beam weight-bearing CT (WBCT) as a major innovation in the foot and ankle realm, becoming an important modality for bone and joint imaging. The ability to provide three-dimensional images of the naturally loaded skeleton has enabled several subsequent innovations to arise with aims to hasten image processing and to extend the clinical applications of WBCT. The objective of this work was to identify, categorize and explain those emerging techniques. We performed a structured review of the literature according to PRISMA standards, finally including 50 studies. We subsequently proposed a classification of these techniques. Segmentation and distance mapping were identified as key features. We conclude that although WBCT has already been adopted in a number of clinical communities with an immediate improvement in patient workflows, adoption of advanced techniques is yet to come. However, that relies mostly not on the technology itself, but on improvements in AI software allowing practitioners to quickly process images in daily practice and enabling the clinicians to obtain an accurate three-dimensional evaluation of the segment considered. Standardization will be paramount to amass large amounts of comparable data, which will fuel further innovations in a potentially virtuous circle.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Foot and Ankle Surgery · Orthopedic Surgery and Rehabilitation · Diabetic Foot Ulcer Assessment and Management
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Foot and Ankle Surgery, Ramsay Healthcare Clinique de l’Union, 31240 Saint Jean, France
Department of Orthopedics, Duke University of Medicine, Durham, NC 27710, USA
Movement Analysis Laboratory, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy
Department of Orthopedic Surgery, Federico II University Hospital, 80131 Napoli, Italy
References (97)
Show source-provided references
1. A new volumetric CT machine for dental imaging based on the cone-beam technique: Preliminary results10.1007/s003300050586 ↗
2. Maximum entropy reconstruction from cone-beam projection data10.1016/0010-4825(79)90020-9 ↗
3. Binary vascular reconstruction from a limited number of cone beam projections10.1118/1.597223 ↗
4. Computerized transverse axial tomography10.1259/0007-1285-46-552-1023 ↗
5. Practical cone-beam algorithms10.1364/JOSAA.1.000612 ↗
6. Development of a subject-standing-type cone-beam computed tomography for chest and orthopedic imaging10.1163/15685570152772450 ↗
7. A dedicated cone-beam CT system for musculoskeletal extremities imaging: Design, optimization, and initial performance characterization10.1118/1.3611039 ↗
8. WE-G-217BCD-04: Diagnostic Image Quality Evaluation of a Dedicated Extremity Cone- Beam CT Scanner: Pre-Clinical Studies and First Clinical Results10.1118/1.4736212 ↗
9. Weight-bearing CT imaging of the lower extremity10.2214/AJR.12.8481 ↗
10. Weightbearing CT scan of severe flexible pes planus deformities10.3113/FAI.2008.0199 ↗
11. The biomechanics of the first metatarsal bone in hallux valgus: A preliminary study utilizing a weight bearing extremity CT10.1016/j.fas.2013.01.003 ↗
12. PedCAT for 3D-imaging in standing position allows for more accurate bone position (angle) measurement than radiographs or CT10.1016/j.fas.2014.04.004 ↗
13. Cost Analysis and Reimbursement of Weightbearing Computed Tomography10.1177/24730114231164143 ↗
14. Assessment of Hindfoot Alignment Comparing Weightbearing Radiography to Weightbearing Computed Tomography10.1177/10711007211014171 ↗
15. Weight-bearing cone-beam CT: The need for standardised acquisition protocols and measurements to fulfill high expectations—A review of the literature10.1007/s00256-022-04223-1 ↗
16. Geometric 3D analyses of the foot and ankle using weight-bearing and non weight-bearing cone-beam CT images: The new standard?10.1016/j.ejrad.2021.109674 ↗
17. Augmented stress weightbearing CT for evaluation of subtle tibiofibular syndesmotic injuries in the elite athlete10.1007/s00256-022-04229-9 ↗
18. Correction of ankle varus deformity using patient-specific dome-shaped osteotomy guides designed on weight-bearing CT: A pilot study10.1007/s00402-021-04164-9 ↗
19. Impact of Coleman Block Test on Adult Hindfoot Alignment Assessed by Clinical Examination, Radiography, and Weight-Bearing Computed Tomography10.1177/2473011420933264 ↗
20. Three-dimensional analysis for quantification of knee joint space width with weight-bearing CT: Comparison with non-weight-bearing CT and weight-bearing radiography10.1016/j.joca.2021.11.019 ↗
21. High Reliability for Semiautomated 3D Measurements Based on Weightbearing CT Scans10.1177/10711007211034522 ↗
22. Angular and linear measurements of adult flexible flatfoot via weight-bearing CT scans and 3D bone reconstruction tools10.1038/s41598-021-95708-x ↗
23. 3D measurement techniques for the hindfoot alignment angle from weight-bearing CT in a clinical population10.1038/s41598-022-21440-9 ↗
24. Richter, M., Zech, S., Naef, I., Duerr, F., and Schilke, R. (2024). Automatic software-based 3D-angular measurement for weight-bearing CT (WBCT) is valid. Foot Ankle Surg.10.1016/j.fas.2024.02.016 ↗
25. An Objective Computational Method to Quantify Ankle Osteoarthritis From Low-Dose Weightbearing Computed Tomography10.1177/24730114221116805 ↗
26. Semi-automated 3-dimensional analysis of the normal foot and ankle using weight bearing CT—A report of normal values and bony relationships10.1016/j.fas.2022.12.001 ↗
27. A Comparison Between X-ray Imaging and an Innovative Computer-aided Design Method Based on Weightbearing CT Scan Images for Assessing Hallux Valgus10.1053/j.jfas.2018.12.044 ↗
28. High-Resolution Cone-Beam Computed Tomography is a Fast and Promising Technique to Quantify Bone Microstructure and Mechanics of the Distal Radius10.1007/s00223-020-00773-5 ↗
29. Upright cone CT of the hindfoot: Comparison of the non-weight-bearing with the upright weight-bearing position10.1007/s00330-013-3028-2 ↗
30. Diagnostic value of cone beam computed tomography (CBCT) in occult scaphoid and wrist fractures10.1016/j.ejrad.2017.10.010 ↗
31. The advantages of cone-beam computerised tomography (CT) in pain management following total knee arthroplasty, in comparison with conventional multi-detector CT10.1016/j.otsr.2021.102874 ↗
32. Impact of introducing extremity cone-beam CT in an emergency radiology department: A population-based study10.1016/j.otsr.2021.102834 ↗
33. Cone-beam computed tomography compared to X-ray in diagnosis of extremities bone fractures: A study of 198 cases10.1016/j.ejro.2019.01.009 ↗
34. Cone-Beam CT of the Extremities in Clinical Practice10.1148/rg.230143 ↗
35. Results of more than 11,000 scans with weightbearing CT—Impact on costs, radiation exposure, and procedure time10.1016/j.fas.2019.05.019 ↗
36. Effective radiation dose of a MSCT, two CBCT and one conventional radiography device in the ankle region10.1186/s13047-015-0067-8 ↗
37. Effective doses in radiology and diagnostic nuclear medicine: A catalog10.1148/radiol.2481071451 ↗
38. Initial Clinical Experience With Extremity Cone-Beam CT of the Foot and Ankle in Pediatric Patients10.2214/AJR.15.15099 ↗
39. A Case-Control Study of 3D vs 2D Weightbearing CT Measurements of the M1-M2 Intermetatarsal Angle in Hallux Valgus10.1177/10711007221091812 ↗
40. A method to incorporate the effect of beam quality on image noise in a digitally reconstructed radiograph (DRR) based computer simulation for optimisation of digital radiography10.1088/1361-6560/aa81fb ↗
41. Flexible Adult Acquired Flatfoot Deformity: Comparison Between Weight-Bearing and Non-Weight-Bearing Measurements Using Cone-Beam Computed Tomography10.2106/JBJS.16.01366 ↗
42. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews10.1186/s13643-021-01626-4 ↗
43. Can Weight-Bearing Computed Tomography Be a Game-Changer in the Assessment of Ankle Sprain and Ankle Instability?10.1016/j.fcl.2023.01.003 ↗
44. Combination of PedCAT Weightbearing CT With Pedography Assessment of the Relationship Between Anatomy-Based Foot Center and Force/Pressure-Based Center of Gravity10.1177/1071100717744206 ↗
45. Subluxation of the Middle Facet of the Subtalar Joint as a Marker of Peritalar Subluxation in Adult Acquired Flatfoot Deformity: A Case-Control Study10.2106/JBJS.19.00073 ↗
46. Consensus for the Use of Weightbearing CT in the Assessment of Progressive Collapsing Foot Deformity10.1177/1071100720950722 ↗
47. Relationship Between Chronic Lateral Ankle Instability and Hindfoot Varus Using Weight-Bearing Cone Beam Computed Tomography10.1177/1071100719858309 ↗
48. 3D Biometrics for Hindfoot Alignment Using Weightbearing CT10.1177/1071100717690806 ↗
49. Statistical shape model-based tibiofibular assessment of syndesmotic ankle lesions using weight-bearing CT10.1002/jor.25318 ↗
50. Interaction of loading and ligament injuries in subtalar joint instability quantified by 3D weightbearing computed tomography10.1002/jor.25126 ↗
51. Templating of Syndesmotic Ankle Lesions by Use of 3D Analysis in Weightbearing and Nonweightbearing CT10.1177/1071100718791834 ↗
52. Evaluation of a Weightbearing CT Artificial Intelligence-Based Automatic Measurement for the M1-M2 Intermetatarsal Angle in Hallux Valgus10.1177/10711007211015177 ↗
53. Semi-automatic software-based 3D-angular measurement for Weight-Bearing CT (WBCT) in the foot provides different angles than measurement by hand10.1016/j.fas.2022.01.001 ↗
54. 2D Manual vs 3D Automated Assessment of Alignment in Normal and Charcot-Marie-Tooth Cavovarus Feet Using Weightbearing CT10.1177/10711007221084308 ↗
55. Comparison between Weightbearing-CT semiautomatic and manual measurements in Hallux Valgus10.1016/j.fas.2022.02.014 ↗
56. Assessment of Progressive Collapsing Foot Deformity Using Semiautomated 3D Measurements Derived from Weightbearing CT Scans10.1177/10711007211049754 ↗
57. Metatarsophalangeal and interphalangeal joint angle measurements on weight-bearing CT images10.1016/j.fas.2023.01.005 ↗
58. Weightbearing CT Analysis of the Transverse Tarsal Joint During Eversion and Inversion10.1177/10711007211034821 ↗
59. Pes cavovarus in Charcot-Marie-Tooth compared to the idiopathic cavovarus foot: A preliminary weightbearing CT analysis10.1016/j.fas.2020.04.004 ↗
60. Techniques for 3D foot bone orientation angles in weight-bearing from cone-beam computed tomography10.1016/j.fas.2020.03.013 ↗
61. Change in the First Cuneiform-Second Metatarsal Distance After Simulated Ligamentous Lisfranc Injury Evaluated by Weightbearing CT Scans10.1177/1071100720938331 ↗
62. Reliability and correlation analysis of computed methods to convert conventional 2D radiological hindfoot measurements to a 3D setting using weightbearing CT10.1007/s11548-018-1727-5 ↗
63. Combination of pedCAT® for 3D Imaging in Standing Position With Pedography Shows No Statistical Correlation of Bone Position With Force/Pressure Distribution10.1053/j.jfas.2015.10.004 ↗
64. Study on the three-dimensional orientation of the posterior facet of the subtalar joint using simulated weight-bearing CT10.1002/jor.24163 ↗
65. 3-D joint space mapping at the ankle from weight-bearing CT: Reproducibility, repeatability, and challenges for standardisation10.1007/s00330-023-09718-6 ↗
66. Weightbearing CT assessment of foot and ankle joints in Pes Planovalgus using distance mapping10.1016/j.fas.2021.10.004 ↗
67. Distance mapping of the foot and ankle joints using weightbearing CT: The cavovarus configuration10.1016/j.fas.2020.05.007 ↗
68. Correlation of 3D Joint Space Width From Weightbearing CT With Outcomes After Intra-articular Calcaneal Fracture10.1177/1071100720933891 ↗
69. Peiffer, M., Ghandour, S., Nassour, N., Taseh, A., Burssens, A., Waryasz, G., Bejarano-Pineda, L., Audenaert, E., Ashkani-Esfahani, S., and DiGiovanni, C.W. (2024). Normative contact mechanics of the ankle Joint: Quantitative assessment utilizing bilateral weightbearing CT. J. Biomech., 168.10.1016/j.jbiomech.2024.112136 ↗
70. Coverage maps demonstrate 3D Chopart joint subluxation in weightbearing CT of progressive collapsing foot deformity10.1038/s41598-022-23638-3 ↗
71. Using area and volume measurement via weightbearing CT to detect Lisfranc instability10.1002/jor.24970 ↗
72. Volume measurements on weightbearing computed tomography can detect subtle syndesmotic instability10.1002/jor.25049 ↗
73. Utility of Volumetric Measurement via Weight-Bearing Computed Tomography Scan to Diagnose Syndesmotic Instability10.1177/1071100720917682 ↗
74. Ashkani-Esfahani, S., Lucchese, O., Bhimani, R., Taseh, A., Waryasz, G., Kerkhoffs, G.M.M., Maas, M., DiGiovanni, C.W., and Guss, D. (2024). Automation improves the efficiency of weightbearing CT scan 3D volumetric assessments of the syndesmosis. Foot Ankle Surg., in press.10.1016/j.fas.2024.05.010 ↗
75. Centre of Rotation of the Human Subtalar Joint Using Weight-Bearing Clinical Computed Tomography10.1038/s41598-020-57912-z ↗
76. Preoperative Guidance With Weight-Bearing Computed Tomography and Patient-Specific Instrumentation in Foot and Ankle Surgery10.1177/15563316211026325 ↗
77. Accuracy of Weightbearing CT Scans for Patient-Specific Instrumentation in Total Ankle Arthroplasty10.1177/24730114211061493 ↗
78. Diagnostic performance of 3D standing CT imaging for detection of knee osteoarthritis features10.1080/00913847.2015.1074854 ↗
79. Impact of Torque on Assessment of Syndesmotic Injuries Using Weightbearing Computed Tomography Scans10.1177/1071100719829720 ↗
80. Torque application helps to diagnose incomplete syndesmotic injuries using weight-bearing computed tomography images10.1007/s00256-019-3155-1 ↗
81. The use of three-dimensional biometric Foot and Ankle Offset to predict additional realignment procedures in total ankle replacement10.1016/j.fas.2022.02.007 ↗
82. 3D, Weightbearing Topographical Study of Periprosthetic Cysts and Alignment in Total Ankle Replacement10.1177/1071100719891411 ↗
83. Subtalar joint configuration on weightbearing CT scan10.1177/1071100714540890 ↗
84. Computed tomography-based radiostereometric analysis in orthopedic research: Practical guidelines10.2340/17453674.2023.15337 ↗
85. Guideline for RSA and CT-RSA implant migration measurements: An update of standardizations and recommendations10.2340/17453674.2024.40709 ↗
86. Measuring hindfoot alignment in weight bearing CT: A novel clinical relevant measurement method10.1016/j.fas.2015.10.002 ↗
87. Lenz, A.L., Strobel, M.A., Anderson, A.M., Fial, A.V., MacWilliams, B.A., Krzak, J.J., and Kruger, K.M. (2021). Assignment of local coordinate systems and methods to calculate tibiotalar and subtalar kinematics: A systematic review. J. Biomech., 120.10.1016/j.jbiomech.2021.110344 ↗
88. Intraobserver and interobserver reliability of cone beam weightbearing semi-automatic three-dimensional measurements in symptomatic pes cavovarus10.1016/j.fas.2019.07.005 ↗
89. Multiparametric 3-D analysis of bone and joint space width at the knee from weight bearing computed tomography10.1016/j.ostima.2022.100069 ↗
90. The Relationship of Three-Dimensional Joint Space Width on Weight Bearing CT With Pain and Physical Function10.1002/jor.24566 ↗
91. Assessment of coronal plane subtalar joint alignment in peritalar subluxation via weight-bearing multiplanar imaging10.1177/1071100714557861 ↗
92. Subluxation of the talocalcaneal joint in adults who have symptomatic flatfoot10.2106/00004623-199908000-00010 ↗
93. Three-Dimensional Distance and Coverage Maps in the Assessment of Peritalar Subluxation in Progressive Collapsing Foot Deformity10.1177/1071100720983227 ↗
94. Impact of the rotational position of the hindfoot on measurements assessing the integrity of the distal tibio-fibular syndesmosis10.1016/j.fas.2019.10.010 ↗
95. CORR Insights®: Can Weightbearing Cone-beam CT Reliably Differentiate Between Stable and Unstable Syndesmotic Ankle Injuries? A Systematic Review and Meta-Analysis10.1097/CORR.0000000000002223 ↗
96. Cone-beam CT measurements of distal tibio-fibular syndesmosis in asymptomatic uninjured ankles: Does weight-bearing matter?10.1007/s00256-018-3074-6 ↗
97. Distal Tibiofibular Syndesmotic Widening in Progressive Collapsing Foot Deformity10.1177/1071100720982907 ↗