journal article·2023-10-13Open access

Liver Tumor Computed Tomography Image Segmentation Based on an Improved U-Net Model

Hefu Li, Binmei Liang

Applied Sciences· Volume 13· Issue 20

Abstract

An automated segmentation method for computed tomography (CT) images of liver tumors is an urgent clinical need. Tumor areas within liver cancer images are easily missed as they are small and have unclear borders. To address these issues, an improved liver tumor segmentation method based on U-Net is proposed. This involves incorporating attention mechanisms into the U-Net’s skip connections, giving higher weights to important regions. Through dynamically adjusting the attention recognition characteristics, the method achieves accurate localization that is focused on and discriminates target regions. Testing using the LiTS (liver tumor segmentation) public dataset resulted in a Dice similarity coefficient of 0.69. The experiments demonstrated that this method can accurately segment liver tumors.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Advanced Neural Network Applications · Medical Image Segmentation Techniques · AI in cancer detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Computer and Electronic Information, Guangxi University, Nanning 530004, China

References (30)

Show source-provided references
1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries10.3322/caac.21492 ↗
2. The liver tumor segmentation benchmark (lits)10.1016/j.media.2022.102680 ↗
3. Zheng, Z., Zhang, X., Xu, H., Liang, W., Zheng, S., and Shi, Y. (2018). A Unified Level Set Framework Combining Hybrid Algorithms for Liver and Liver Tumor Segmentation in CT Images. BioMed Res. Int., 2018.10.1155/2018/3815346 ↗
4. CT liver tumor segmentation hybrid approach using neutrosophic sets, fast fuzzy c-means and adaptive watershed algorithm—ScienceDirect10.1016/j.artmed.2018.11.007 ↗
5. CT liver image segmentation based on regional growth and unified levelset
6. Spatial feature fusion convolutional network for liver and liver tumor segmentation from CT images10.1002/mp.14585 ↗
7. Liver Tumor Segmentation Algorithm Based on Improved V-Net Model
8. An automatic liver segmentation method based on optimized tree model
9. H-DenseUNet: Hybrid Densely Connected UNet for Liver and Tumor Segmentation From CT Volumes10.1109/TMI.2018.2845918 ↗
10. U-Next: A novel convolution neural network with an aggregation U-Net architecture for gallstone segmentation in CT images10.1109/ACCESS.2019.2953934 ↗
11. Zhang, Z., Wu, C., Coleman, S., and Kerr, D. (2020). DENSE-INception U-net for medical image segmentation. Comput. Methods Programs Biomed., 192.10.1016/j.cmpb.2020.105395 ↗
12. Ronneberger, O., Fischer, P., and Brox, T. (2015). U-Net: Convolutional Networks for Biomedical Image Segmentation, Springer International Publishing.10.1007/978-3-319-24574-4_28 ↗
13. Automatic Liver Lesion Segmentation Using A Deep Convolutional Neural Network Method10.1002/mp.12155 ↗
14. Huang, G., Liu, Z., Van Der Maaten, L., and Weinberger, K.Q. (2017–26, January 21). Densely Connected Convolutional Networks. Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, Honolulu, HI, USA.10.1109/CVPR.2017.243 ↗
15. Medical image classification using synergic deep learning10.1016/j.media.2019.02.010 ↗
16. Cervical cancer classification using convolutional neural networks and extreme learning machines10.1016/j.future.2019.09.015 ↗
17. Automatic liver and tumour segmentation from CT images using Deep learning algorithm10.1016/j.rico.2021.100087 ↗
18. Vaswani, A., Shazeer, N., Parmar, N., Uszkoreit, J., Jones, L., Gomez, A.N., Kaiser, Ł., and Polosukhin, I. (2017). Attention Is All You Need. arXiv.
19. Wang, X., Girshick, R., Gupta, A., and He, K. (2018, January 18–23). Non-local Neural Networks. Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, Salt Lake City, UT, USA.10.1109/CVPR.2018.00813 ↗
20. Feature selection and residual fusion segmentation network for liver tumor10.11834/jig.210250 ↗
21. Dosovitskiy, A., Beyer, L., Kolesnikov, A., Weissenborn, D., Zhai, X., Unterthiner, T., Dehghani, M., Minderer, M., Heigold, G., and Gelly, S. (2020). An Image is Worth 16 × 16 Words: Transformers for Image Recognition at Scale. arXiv.
22. Li, L., and Ma, H. (2022). RDCTrans U-Net: A Hybrid Variable Architecture for Liver CT Image Segmentation. Sensors, 22.10.3390/s22072452 ↗
23. U-Net and Its Variants for Medical Image Segmentation: A Review of Theory and Applications10.1109/ACCESS.2021.3086020 ↗
24. Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., and Ronneberger, O. (2016). 3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation, Springer.10.1007/978-3-319-46723-8_49 ↗
25. Wang, X., Han, S., Chen, Y., Gao, D., and Vasconcelos, N. (2020, January 4–8). Volumetric Attention for 3D Medical Image Segmentation and Detection. Proceedings of the International Conference on Medical Image Computing and Computer-Assisted Intervention, Lima, Peru.10.1007/978-3-030-32226-7_20 ↗
26. Ma, J. (2021). Cutting-edge 3D Medical Image Segmentation Methods in 2020: Are Happy Families All Alike?. arXiv.
27. He, K., Zhang, X., Ren, S., and Sun, J. (2016, January 27–30). Deep residual learning for image recognition. Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR), Las Vegas, NV, USA.10.1109/CVPR.2016.90 ↗
28. Hu, J., Shen, L., and Sun, G. (2018, January 18–23). Squeeze-and-Excitation Networks. Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition (CVPR), Salt Lake City, UT, USA.10.1109/CVPR.2018.00745 ↗
29. Dey, R., and Hong, Y. (2020, January 3–7). Hybrid cascaded neural network for liverlesion segmentation. Proceedings of the 17th IEEE International Symposium on Biomedical Imaging(ISBI), Iowa City, IA, USA.10.1109/ISBI45749.2020.9098656 ↗
30. Multi-scale self-guided attention for medical image segmentation10.1109/JBHI.2020.2986926 ↗