Potential Prebiotic and Anti-Obesity Effects of Codium fragile Extract
Source abstract
Abstract
Polysaccharides from marine algae exhibit beneficial biological activities. In this study, we examined the effect of Codium fragile extract (CFE) on prebiotic and anti-obesity activity through in vitro experiments. CFE increases the growth of specific beneficial microbial populations with concomitant decrease in pathogenic microbes. Further, total phenolic content (TPC), total flavonoid content (TFC), and DPPH radical scavenging activity (DPPH activity) after fermentation with CFE as the carbon source were higher than for glucose as the control. Moreover, CFE inhibited adipocyte differentiation by inducing differentiation-related factors when the induction of 3T3-L1 preadipocytes into adipocytes was induced. Therefore, we suggest that CFE can be used as a prebiotic material with an anti-obesity effect for human health.
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Research context
OpenAlex topics: Seaweed-derived Bioactive Compounds · Microbial Metabolites in Food Biotechnology · Algal biology and biofuel production
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Marine Biotechnology Research Center, Jeonnam Bioindustry Foundation, 21-7, Nonggongdanji 4Gil, Wando-eup, Wando-gun 59108, Korea
Department of Biotechnology, Chonnam National University, Yeosu-si 59626, Korea
Bada and Haecho Fishery Crorp., 1111-2, Cheonma-ro, Pungyang-myeon, Goheung-gun 59548, Korea
Funding
Small and Medium Business Administration
References (68)
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