journal article·2021-09-06Open access

Theoretical Evaluation of Microwave Ablation Applied on Muscle, Fat and Bone: A Numerical Study

Cheng Chen, Ming-An Yu, Lin Qiu, Hong-Yu Chen, Zhen-Long Zhao, Jie Wu, Li-Li Peng, Zhi-Liang Wang, Ruo-Xiu Xiao

Applied Sciences· Volume 11· Issue 17

Abstract

(1) Background: Microwave ablation (MWA) is a common tumor ablation surgery. Because of the high temperature of the ablation antenna, it is strongly destructive to surrounding vital tissues, resulting in high professional requirements for clinicians. The method used to carry out temperature observation and damage prediction in MWA is significant; (2) Methods: This work employs numerical study to explore temperature distribution of typical tissues in MWA. Firstly, clinical MWA based on isolated biological tissue is implemented. Then, the Pennes models and microwave radiation physics are established based on experimental parameters and existing related research. Initial values and boundary conditions are adjusted to better meet the real clinical materials and experimental conditions. Finally, clinical MWA data test this model. On the premise that the model is matched with clinical MWA, fat and bone are deduced for further heat transfer analysis. (3) Results: Numerical study obtains the temperature distribution of biological tissue in MWA. It observes the heat transfer law of ablation antenna in biological tissue. Additionally, combined with temperature threshold, it generates thermal damage of biological tissues and predicts the possible risks in MWA; (4) Conclusions: This work proposes a numerical study of typical biological tissues. It provides a new theoretical basis for clinically thermal ablation surgery.
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Research context

OpenAlex topics: Ultrasound and Hyperthermia Applications · Infrared Thermography in Medicine · Thermoelastic and Magnetoelastic Phenomena

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Internet of Things and Electronic Engineering, School of Computer and Communication Engineering, University of Science and Technology Beijing, Beijing 100083, China

Interventional Medicine, China-Japan Friendship Hospital, Beijing 100029, China

Department of Thermal Science and Energy Engineering, School of Energy and Environmental Engineering, University of Science and Technology Beijing, Beijing 100083, China

Institute of Artificial Intelligence, University of Science and Technology Beijing, Beijing 100083, China

Funding

National Key Research and Development Program · Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences · Beijing Nova Program · Beijing Municipal Science & Technology Commission · Beijing University of Chemical Technology-China-Japan Friendship Hospital Biomedical Trans-formation Joint Fund Project · Capital health research and development project · Fundamental Research Funds for the Central Universities

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