Acoustic Voice and Speech Biomarkers of Treatment Status during Hospitalization for Acute Decompensated Heart Failure
Source abstract
Abstract
This study investigates acoustic voice and speech features as biomarkers for acute decompensated heart failure (ADHF), a serious escalation of heart failure symptoms including breathlessness and fatigue. ADHF-related systemic fluid accumulation in the lungs and laryngeal tissues is hypothesized to affect phonation and respiration for speech. A set of daily spoken recordings from 52 patients undergoing inpatient ADHF treatment was analyzed to identify voice and speech biomarkers for ADHF and to examine the trajectory of biomarkers during treatment. Results indicated that speakers produce more stable phonation, a more creaky voice, faster speech rates, and longer phrases after ADHF treatment compared to their pre-treatment voices. This project builds on work to develop a method of monitoring ADHF using speech biomarkers and presents a more detailed understanding of relevant voice and speech features.
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Research context
OpenAlex topics: Voice and Speech Disorders · Phonocardiography and Auscultation Techniques · Respiratory and Cough-Related Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Center for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA
Speech and Hearing Bioscience and Technology, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA
MGH Institute of Health Professions, Boston, MA 02129, USA
Institute for Heart, Vascular, and Stroke Care, Massachusetts General Hospital, Boston, MA 02114, USA
Department of Surgery, Harvard Medical School, Boston, MA 02115, USA
Biofourmis, Inc., Boston, MA 02110, USA
Division of Cardiovascular Medicine, Oregon Health & Science University, Portland, OR 97239, USA
Computer Science & Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Funding
Center for Assessment Technology and Continuous Health (CATCH) at Massachusetts General Hospital · NIH National Heart, Lung, and Blood Institute · Voice Health Institute
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