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journal article·2026-02Open access

A plasmonic and intelligent sweat sensing patch for large‐scale health monitoring

Yuanchao Liu, Binbin Zhou, Gang Xu, Wei Luo, Xiujuan Hu, Feiyu Guan, Shengqun Shi, Zhixing Ge, Shaofei Shen, Annan Chen, Lianbo Guo, Condon Lau, Chwee Teck Lim, Jian Lu

InfoMat· Volume 8· Issue 2
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Source abstract

Abstract

Abstract The need for rapid and comprehensive health monitoring is especially critical during health crises involving chronic diseases of epidemic proportions or infectious disease outbreaks. Sweat testing offers a rapid, in situ, and noninvasive alternative to traditional blood testing, minimizing discomfort and cross‐infection risks. However, the development and commercialization of simple, highly scalable, and power‐free sweat sensing devices have been slow and challenging. Here, we design a miniaturized, modular, and skin‐interfaced sweat sensing patch for rapid and efficient large‐scale health monitoring and diagnosis through multimodal laser sensing. The patch's workflow involves sweat collection via a microfluidics‐based collection module, followed by sweat sensing and artificial intelligence (AI)‐assisted diagnosis. The sweat sensing module, prepared by coating silver nanowires on filter paper, enables rapid detection of multi‐analytes (e.g., glucose, lactate, urea, sodium, potassium, and lead) using multimodal laser sensing techniques (that combine surface‐enhanced Raman spectroscopy with nano‐enhanced laser‐induced breakdown spectroscopy). Furthermore, the multispectral data, analyzed with AI assistance, can rapidly and efficiently detect abnormalities in sweat components for quick diagnosis. Our volunteer trials also show that real‐world health monitoring is feasible. Overall, this straightforward and cost‐effective patch, integrated with multimodal laser sensing, can potentially enable large‐scale health monitoring and diagnosis. image
Source: crossref · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Biosensors and Analytical Detection · Surface Modification and Superhydrophobicity

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Mechanical Engineering City University of Hong Kong Kowloon Hong Kong SAR The People's Republic of China

Shenzhen Institute of Advanced Electronic Materials, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences Shenzhen The People's Republic of China

School of Optical and Electronic Information Huazhong University of Science and Technology Wuhan The People's Republic of China

School of Integrated Circuits Huazhong University of Science and Technology Wuhan The People's Republic of China

Department of Physics City University of Hong Kong Kowloon Hong Kong SAR The People's Republic of China

Wuhan National Laboratory for Optoelectronics (WNLO) Huazhong University of Science and Technology Wuhan The People's Republic of China

Institute for Health Innovation and Technology, National University of Singapore Singapore Singapore

Shanxi Key Lab for Modernization of TCVM College of Life Science, Shanxi Agricultural University Taigu Shanxi The People's Republic of China

Department of Biomedical Engineering National University of Singapore Singapore Singapore

Hong Kong Branch of National Precious Metals Material Engineering Research Centre, City University of Hong Kong Hong Kong SAR The People's Republic of China

Funding

National Natural Science Foundation of China · City University of Hong Kong

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