Prospects of Novel Technologies for PFAS Destruction in Water and Wastewater
Source abstract
Abstract
PFASs, compounds to which the C-F bond—the strongest known in nature—bestows high resistance to degradation, have been detected in surface and groundwater worldwide, including drinking water supplies. Current regulations on long-chain PFASs resulted in the shift to short-chain PFASs in industrial uses, with their increasing environmental detection. Currently, suggested BATs for PFAS removal from aqueous solutions include mainly adsorption or membrane filtration; however, different response behavior to even simple treatment was observed concerning long- and short-chain PFAS molecules. In order to permanently destroy (mineralize) PFASs and their precursors, treatment technologies that can deliver sufficiently high energy to crack the C-F bond are needed. This paper discusses current PFAS removal technologies and state of the art advanced methods for PFAS removal and destruction, critically discussing their efficiency, applicability, emerging issues, and future prospects.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Per- and polyfluoroalkyl substances research · Toxic Organic Pollutants Impact · Luminescence and Fluorescent Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
DICAR, University of Pavia, 27100 Pavia, Italy
References (100+)
Show source-provided references
1. EEA (2025, June 18). PFAS Contamination in Europe. Available online: https://www.eea.europa.eu/en/european-zero-pollution-dashboards/indicators/treatment-of-drinking-water-to-remove-pfas-signal.
2. Blake, M. (2025). They Poisoned the World, Random House.
3. A nationwide survey of perfluorinated alkyl substances in waters, sediment and biota collected from aquatic environment in Vietnam: Distributions and bioconcentration profiles10.1016/j.jhazmat.2016.04.010 ↗
4. Microplastics in the urban water cycle: A critical analysis of issues and of possible (needed?) solutions10.1016/j.scitotenv.2024.176580 ↗
5. Distribution, transformation and remediation of poly- and per-fluoroalkyl substances (PFAS) in wastewater sources10.1016/j.psep.2022.06.002 ↗
6. Modiri, M., Sasi, P., Crone, B., Potter, P., Van Buren, J., Doroshow, A., Voit, J., and Mills, M.A. (2024). PFAS Precursors in Wastewater, University of Cincinnati Department of Chemical and Environmental Engineering Graduate Seminar.
7. A review of the occurrence, transformation, and removal of poly-and perfluoroalkyl substances (PFAS) in wastewater treatment plants10.1016/j.watres.2021.117187 ↗
8. Exploring unknown per- and polyfluoroalkyl substances in the German environment–The total oxidizable precursor assay as helpful tool in research and regulation10.1016/j.scitotenv.2021.146825 ↗
9. Accumulation of perfluorinated alkyl substances (PFAS) in agricultural plants: A review10.1016/j.envres.2018.10.023 ↗
10. Per- and Polyfluoroalkyl Substances (PFAS) in PubChem: 7 Million and Growing10.1021/acs.est.3c04855 ↗
11. NIH (2025, June 16). Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS). National Institute of Health, Available online: https://www.niehs.nih.gov/health/topics/agents/pfc.
12. US EPA (2024). Per- and Polyfluoroalkyl Substances (PFAS) Final. PFAS National Primary Drinking Water Regulation. 40 CFR Parts 141 and 142, ANHE.
13. Short-chain per- and polyfluoroalkyl substances in aquatic systems: Occurrence, impacts and treatment10.1016/j.cej.2019.122506 ↗
14. Short-chain perfluoroalkyl acids: Environmental concerns and a regulatory strategy under REACH10.1186/s12302-018-0134-4 ↗
15. Simultaneous analysis of perfluoroalkyl and polyfluoroalkyl substances including ultrashort-chain C2 and C3 compounds in rain and river water samples by ultra performance convergence chromatography10.1016/j.chroma.2017.09.049 ↗
16. Photochemical reactivity of perfluorooctanoic acid (PFOA) in conditions representing surface water10.1016/j.scitotenv.2011.04.036 ↗
17. 6:2 Fluorotelomer sulfonate aerobic biotransformation in activated sludge of waste water treatment plants10.1016/j.chemosphere.2010.11.003 ↗
18. Capodaglio, A.G. (2025). Micro- and Nano-Plastics in DrinkingWater: Threat or Hype?. Critical State-of-the-Art Analysis of Risks and Approaches. Xenobiotics, 15.10.3390/jox15030085 ↗
19. Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science and a Proposed Path Forward10.1002/etc.4869 ↗
20. US EPA (2024). Best Available Technologies and Small System Compliance Technologies for Per- and Polyfluoroalkyl Substances (PFAS) in Drinking Water. EPA Document Number: 815R24011. U.S. Environmental Protection Agency. Office of Water.
21. Early breakthrough of short-chain perfluoroalkyl substances in adsorptive media treatment10.1002/rem.21717 ↗
22. Bond dissociation energies of organic molecules10.1021/ar020230d ↗
23. Computing accurate bond dissociation energies of emerging per- and polyfluoroalkyl substances: Achieving chemical accuracy using connectivity-based hierarchy schemes10.1016/j.jhazmat.2024.133804 ↗
24. Bond dissociation energy of the phenol OH bond from ab initio calculations10.1016/j.cplett.2006.04.022 ↗
25. Understanding organofluorine chemistry. An introduction to the C–F bond10.1039/B711844A ↗
26. Kirsch, P. (2004). Modern Fluoroorganic Chemistry, Wiley-VCH Verlag GmbH & Co. KGaA.
27. Capodaglio, A.G. (2019). Contaminants of emerging concern removal by high-energy oxidation-reduction processes: State of the art. Appl. Sci., 9.10.3390/app9214562 ↗
28. High energy radiation – Induced cooperative reductive/oxidative mechanism of perfluorooctanoate anion (PFOA) decomposition in aqueous solution10.1016/j.chemosphere.2022.133920 ↗
29. Benchmark DFT studies on C–CN homolytic cleavage and screening the substitution effect on bond dissociation energy10.1007/s00894-019-3930-x ↗
30. Exploring an accurate machine learning model to quickly estimate stability of diverse energetic materials10.1016/j.isci.2024.109452 ↗
31. Figures-of-merit for the technical development and application of advanced oxidation technologies for both electric- and solar-driven systems (IUPAC Technical Report)10.1351/pac200173040627 ↗
32. Meegoda, J.N., de Souza, B.B., Casarini, M.M., and Kewalramani, J.A. (2022). A Review of PFAS Destruction Technologies. Int. J. Environ. Res. Public. Health, 19.10.3390/ijerph192416397 ↗
33. Detection, occurrence, and fate of fluorotelomer alcohols in municipal wastewater treatment plants10.1021/acs.est.7b00315 ↗
34. Occurrence and fate of perfluorinated acids in two wastewater treatment plants in Shanghai, China10.1007/s11356-013-2044-8 ↗
35. Per- and polyfluoroalkyl substances in water and soil in wastewater-irrigated farmland in Jordan10.1016/j.scitotenv.2020.137057 ↗
36. A mass estimate of Perfluoroalkyl Substance (PFAS) release from Australian wastewater treatment plants10.1016/j.chemosphere.2018.06.024 ↗
37. Which type of pollutants need to be controlled with priority in wastewater treatment plants: Traditional or emerging pollutants?10.1016/j.envint.2019.104982 ↗
38. Evaluation of the efficiency of selected wastewater treatment processes in removing selected perfluoroalkyl substances (PFASs)10.1016/j.jenvman.2019.109945 ↗
39. Linking PFAS partitioning behavior in sewage solids to the solid characteristics, solution chemistry, and treatment processes10.1016/j.chemosphere.2020.129530 ↗
40. Review of influence of critical operation conditions on by-product/intermediate formation during thermal destruction of PFAS in solid/biosolids10.1016/j.scitotenv.2022.158796 ↗
41. Legacy and emerging per- and polyfluoroalkyl substances (PFASs) in Australian biosolids10.1016/j.chemosphere.2020.129143 ↗
42. Perfluoroalkyl substances (PFAS) adsorption in drinking water by granular activated carbon: Influence of activated carbon and PFAS characteristics10.1016/j.scitotenv.2021.148821 ↗
43. Removal efficiency of multiple poly-and perfluoroalkyl substances (PFASs) in drinking water using granular activated carbon (GAC) and anion exchange (AE) column tests10.1016/j.watres.2017.04.057 ↗
44. Removal of per-and polyfluoroalkyl substances using super-fine powder activated carbon and ceramic membrane filtration10.1016/j.jhazmat.2018.11.050 ↗
45. Adsorption behavior and mechanism of perfluorinated compounds on various adsorbents—A review10.1016/j.jhazmat.2014.04.038 ↗
46. Regeneration of exhausted adsorbents after PFAS adsorption: A critical review10.1016/j.jhazmat.2024.134429 ↗
47. Exploring the factors that influence the adsorption of anionic PFAS on conventional and emerging adsorbents in aquatic matrices10.1016/j.watres.2020.115950 ↗
48. A review of PFAS adsorption from aqueous solutions: Current approaches, engineering applications, challenges, and opportunities10.1016/j.envpol.2023.121138 ↗
49. Synthesis of a perfluorooctanoic acid molecularly imprinted polymer for the selective removal of perfluorooctanoic acid in an aqueous environment10.1002/app.43192 ↗
50. Covalent organic frameworks: A review of synthesis methods, properties and applications for per- and poly-fluoroalkyl substances removal10.1007/s10098-024-03102-8 ↗
51. Sorption of Perfluorinated Compounds onto different types of sewage sludge and assessment of its importance during wastewater treatment10.1016/j.chemosphere.2014.03.087 ↗
52. Green sorption media for the removal of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) from water10.1016/j.scitotenv.2021.152886 ↗
53. Adsorption as a remediation technology for short-chain per- and polyfluoroalkyl substances (PFAS) from water—A critical review10.1039/D2EW00721E ↗
54. Regeneration of per- and polyfluoroalkyl substance-laden granular activated carbon using a solvent based technology10.1016/j.jenvman.2021.112439 ↗
55. PFAS removal by ion exchange resins: A review10.1016/j.chemosphere.2021.129777 ↗
56. Fit-for-purpose urban wastewater reuse: Analysis of issues and available technologies for sustainable multiple barrier approaches10.1080/10643389.2020.1763231 ↗
57. Cross-Flow Treatment of PFAS in Water: Materials Challenges and Potential Solutions10.1021/accountsmr.0c00106 ↗
58. Development of ceramic membranes with controllable PFAS mass transfer for passive sampling applications10.1016/j.ceja.2023.100562 ↗
59. Structure and mechanism of nanoengineered membranes toward per- and polyfluoroalkyl substances (PFAS) removal from water: A critical review10.1016/j.jwpe.2024.105471 ↗
60. Breaking Down Barriers: Innovations in PFAS Destruction
61. High-energy oxidation process: An efficient alternative for wastewater organic contaminants removal10.1007/s10098-017-1410-5 ↗
62. Understanding and managing the potential by-products of PFAS destruction10.1111/gwmr.12372 ↗
63. Treatment technologies for aqueous perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA)10.1007/s11783-009-0022-7 ↗
64. Gas-phase NMR technique for studying the thermolysis of materials: Thermal decomposition of ammonium perfluorooctanoate10.1021/ac049667k ↗
65. Yamada, T., and Taylor, P. (2003). Laboratory Scale Thermal Degradation of PFOS and Related Precoursors, University of Dayton Research Institute (UDRI). Final Report—UDR-TR-03-00044.
66. Rapid destruction and defluorination of perfluorooctanesulfonate by alkaline hydrothermal reaction10.1021/acs.estlett.9b00506 ↗
67. Per- and polyfluoroalkyl substances thermal destruction at water resource recovery facilities: A state of the science review10.1002/wer.1483 ↗
68. Thermal mineralization behavior of PFOA, PFHxA, and PFOS during reactivation of granular activated carbon (GAC) in nitrogen atmosphere10.1007/s11356-015-5353-2 ↗
69. Residual organic fluorinated compounds from thermal treatment of PFOA, PFHxA and PFOS adsorbed onto granular activated carbon (GAC)10.1007/s10163-016-0532-x ↗
70. Destruction of perfluorooctanoic acid (PFOA) and perfluorooctadecanoic acid (PFOcDA) by incineration: Analysis of the by-products and their characteristics10.1016/j.chemosphere.2025.144165 ↗
71. Capodaglio, A.G., and Olsson, G. (2020). Energy issues in sustainable urban wastewater management: Use, demand reduction and recovery in the urban water cycle. Sustainability, 12.10.3390/su12010266 ↗
72. US EPA (2020). Per- and Polyfluoroalkyl Substances (PFAS): Incineration to Manage PFAS Waste Streams, US EPA Tech. Brief EPA-452-F/03-022.
73. GHD (2025, August 17). Understanding the US DoD’s Prohibition of AFFF Incineration and Your Disposal Responsibilities. Available online: https://www.ghd.com/en-au/insights/us-department-of-defenses-prohibition-of-afff-incineration.
74. Production of energy (biodiesel) and recovery of materials (biochar) from pyrolysis of urban waste sludge10.4136/ambi-agua.2128 ↗
75. Removal of PFASs from biosolids using a semi-pilot scale pyrolysis reactor and the application of biosolids derived biochar for the removal of PFASs from contaminated water10.1039/D0EW00763C ↗
76. Pyrolysis transports, and transforms, PFAS from biosolids to py-liquid10.1039/D2EW00677D ↗
77. Pyrolysis processing of PFAS-impacted biosolids, a pilot study10.1080/10962247.2021.2009935 ↗
78. (2025, July 21). Wikipedia. Available online: https://en.wikipedia.org/wiki/Electromagnetic_radiation.
79. Treatment of perfluoroalkyl acids by heat-activated persulfate under conditions representative of in situ chemical oxidation10.1016/j.chemosphere.2018.04.128 ↗
80. Defluorination of per- and polyfluoroalkyl substances (PFASs) with hydrated electrons: Structural dependence and implications to PFAS remediation and management10.1021/acs.est.8b06648 ↗
81. Reductive defluorination of perfluorooctanoic acid by hydrated electrons in a sulfite-mediated UV photochemical system10.1016/j.jhazmat.2013.08.059 ↗
82. Destruction of Per- and Polyfluoroalkyl Substances (PFAS) with Advanced Reduction Processes (ARPs): A Critical Review10.1021/acs.est.9b05565 ↗
83. Can radiation chemistry supply a highly efficient AO(R)P process for organics removal from drinking and waste water? A review10.1007/s11356-017-9836-1 ↗
84. Energy Evaluation of Electron Beam Treatment of Perfluoroalkyl Substances in Water: A Critical Review10.1021/acsestengg.0c00222 ↗
85. Advanced Oxidation/Reduction Processes treatment for aqueous perfluorooctanoate (PFOA) and perfluorooctanesulfonate (PFOS)—a review of recent advances10.1016/j.cej.2017.10.153 ↗
86. Venkatesan, A.K., Cooper, C., Paquette, D., Mills, M.A., Londhe, K., Lee, C.S., and Grdanovska, S. (2021). Application of Electron Beam Technology to Decompose Persistent Emerging Drinking Water Contaminants: Poly- and Perfluoroalkyl Substances (PFAS) and 1,4-Dioxane, State University of New York. Final Report, Award #DE-SC0020277.10.2172/1837061 ↗
87. Application of ionizing radiation in decomposition of perfluorooctanoate (PFOA) in waters10.1016/j.cej.2018.09.065 ↗
88. Could EB irradiation be the simplest solution for removing emerging contaminants from water and wastewater?10.2166/wpt.2018.027 ↗
89. Capodaglio, A.G. (2020). Critical perspective on advanced treatment processes for water and wastewater: AOPs, ARPs, and AORPs. Appl. Sci., 10.10.3390/app10134549 ↗
90. Field Demonstration of a Pilot-Scale Plasma Reactor for the Rapid Removal of Poly- and Perfluoroalkyl Substances in Groundwater10.1021/acsestwater.0c00170 ↗
91. Plasma-based water treatment: Efficient transformation of perfluoroalkyl substances in prepared solutions and contaminated groundwater10.1021/acs.est.6b04215 ↗
92. Rapid removal of poly- and perfluorinated compounds from investigation- derived waste (IDW) in a pilot-scale plasma reactor10.1021/acs.est.9b02964 ↗
93. Challenges and opportunities for electrochemical processes as next-generation technologies for the treatment of contaminated water10.1021/acs.est.5b02414 ↗
94. Scaling up water treatment technologies for PFAS destruction: Current status and potential for fit-for-purpose application10.1016/j.coche.2023.100944 ↗
95. Electrochemical advanced oxidation processes (EAOP) to degrade per- and polyfluoroalkyl substances (PFASs)
96. Electrochemical advanced oxidation of per- and polyfluoroalkyl substances (PFASs): Development, challenges and perspectives10.1016/j.cej.2024.157222 ↗
97. Maldonado, V.Y., Becker, M.F., Nickelsen, M.G., and Witt, S.E. (2021). Laboratory and semi-pilot scale study on the electrochemical treatment of perfluoroalkyl acids from ion exchange still bottoms. Water, 13.10.3390/w13202873 ↗
98. Degradation of per- and polyfluoroalkyl substances (PFAS) in wastewater effluents by photocatalysis for water reuse10.1016/j.jwpe.2021.102556 ↗
99. Cecconet, D., Sturini, M., Malavasi, L., and Capodaglio, A.G. (2021). Graphitic carbon nitride as a sustainable photocatalyst material for pollutants removal. State-of-the art, preliminary tests and application perspectives. Materials, 14.10.3390/ma14237368 ↗
100. Adsorption and solid-phase photocatalytic degradation of perfluorooctane sulfonate in water using gallium-doped carbon-modified titanate nanotubes10.1016/j.cej.2021.129676 ↗