Recent Progress and Challenges Regarding Magnetite-Based Nanoparticles for Targeted Drug Delivery
Source abstract
Abstract
Magnetite-based nanoparticles are of constant interest in the scientific community as potential systems for biomedical applications. Over the years, the ability to synthesize diverse systems based on iron (II, III) oxide nanoparticles has been mastered to maximize their potential effectiveness in the targeted delivery of active substances in cancer therapy. The present review explores recent literature findings that detail various magnetic nanosystems. These encompass straightforward designs featuring a polymer coating on the magnetic core and more intricate matrices for delivering chemotherapeutic drugs. This paper emphasizes novel synthetic approaches that impact the efficacy and progress of anticancer investigations, specifically targeting a particular cancer type. The research also delves into combinations with alternative treatment methods and diagnostic approaches. Additionally, it highlights a critical aspect—the interaction with cells—identifying it as the least developed aspect in current research on these systems.
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Research context
OpenAlex topics: Nanoparticle-Based Drug Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland
Faculty of Physics, Adam Mickiewicz University, Uniwersytetu Poznańskiego 2, 61-614 Poznań, Poland
Funding
National Science Centre
References (100+)
Show source-provided references
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