journal article·2024-02-16Open access

A Survey of Preservatives Used in Cosmetic Products

Patrycja Poddębniak, Urszula Kalinowska-Lis

Applied Sciences· Volume 14· Issue 4

Abstract

The aim of this study was to indicate the type of preservatives used in selected categories of cosmetic products sold in Poland (part of the EU market) and determine the frequency of their use. The tested products consisted of 200 leave-on cosmetics, viz. body lotions (n = 100) and face creams (n = 100) and rinse-off cosmetics (n = 100) and mascaras (n = 25). The product labels of 325 adult cosmetic products from international brands were analyzed for the presence of preservatives based on the INCI compositions. The survey focused on preservatives included in Annex V of the Regulation (EC) No. 1223/2009 of the European Parliament and Council of 30 November 2009 on cosmetic products. The tested products contained 29 different preservatives belonging to eight chemical groups. Most preservatives were alcohols or their derivatives, carboxylic acids or their salts, or parabens. The most common types were phenoxyethanol, present in 198/325 (60.9%) formulations, followed by sodium benzoate, in 137 (42.2%), potassium sorbate, in 116 (35.7%), benzyl alcohol, in 76 (23.4%), and methylparaben in 33 (10.2%). Also, 33 of the 60 preservatives included in Annex V of Regulation (EC) No. 1223/2009 were not used in any of the tested preparations. In each category of products, the most common were combinations of two preservatives per single product (34.8% of all products), followed by single-preservative products (25.5%) and three-preservative products (19.4%).
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Chemistry and Chemical Engineering · Dyeing and Modifying Textile Fibers · Antimicrobial agents and applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Cosmetic Raw Materials Chemistry, Faculty of Pharmacy, Medical University of Lodz, 90-419 Łódź, Poland

Funding

Medical University of Lodz

References (33)

Show source-provided references
1. Controversy around parabens: Alternative strategies for preservative use in cosmetics and personal care products10.1016/j.envres.2020.110488 ↗
2. Preservatives in cosmetics technology10.52336/acm.2023.008 ↗
3. Preservatives in personal hygiene and cosmetic products, topical medications, and household cleaners in Spain
4. Allergic contact dermatitis caused by cosmetic products10.1016/j.ad.2013.12.018 ↗
5. Halla, N., Fernandes, I.P., Heleno, S.A., Costa, P., Boucherit-Otmani, Z., Boucherit, K., Rodrigues, A.E., Ferreira, I.C.F.R., and Barreiro, M.F. (2018). Cosmetic preservation: A review on present strategies. Molecules, 23.10.3390/molecules23071571 ↗
6. European Commission (2009). Regulation
7. (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on Cosmetic Products, Publications Office of the European Union. Official Journal of the European Union L 342/59.
8. Methylparaben potentiates UV-induced damage of skin keratinocytes10.1016/j.tox.2006.07.018 ↗
9. An overview of parabens and allergic contact dermatitis
10. Thimerosal—Clinical, epidemiologic and biochemical studies10.1016/j.cca.2015.02.030 ↗
11. Integrated approaches to testing and assessment as a tool for the hazard assessment and risk characterization of cosmetic preservatives10.1002/jat.4156 ↗
12. Salama, P., and Gliksberg, A. (2021). The Use of Catalytic Amounts of Selected Cationic Surfactants in the Design of New Synergistic Preservative Solutions. Cosmetics, 8.10.3390/cosmetics8020054 ↗
13. Antimicrobial Ingredients as Preservative Booster and Components of Self-Preserving Cosmetic Products10.1007/s00284-018-1492-2 ↗
14. Langsrud, S., Steinhauer, K., Lüthje, S., Weber, K., Goroncy-Bermes, P., and Holck, A.L. (2016). Ethylhexylglycerin Impairs Membrane Integrity and Enhances the Lethal Effect of Phenoxyethanol. PLoS ONE, 11.10.1371/journal.pone.0165228 ↗
15. Monarda essential oils as natural cosmetic preservative systems
16. Essential oils used in dermocosmetics: Review about its biological activities10.1111/jocd.14652 ↗
17. Essential oils and herbal extracts as antimicrobial agents in cosmetic emulsion10.1007/s12088-012-0329-0 ↗
18. IFRA (The International Fragrance Association) Standards 51th Amendment (January 2024), IFRA. Available online: https://ifrafragrance.org/docs/default-source/51st-amendment/ifra-standards---51st-amendment.pdf?sfvrsn=9bc6a23b_0.
19. SCCS (Scientific Committee on Consumer Safety) (2012). SCCS Opinion on Fragrance Allergens in Cosmetic Products, 2012 (SCCS/1459/11), SCCS.
20. Skin Safety and health prevention: An overview of chemicals in cosmetic products
21. SCCS (Scientific Committee on Consumer Safety) (2016). Opinion on Phenoxyethanol, 16 March 2016, Final Version of 6 October 2016, SCCS/1575/16, SCCS.
22. Safety review of phenoxyethanol when used as a preservative in cosmetics10.1111/jdv.15944 ↗
23. Contact allergy to preservatives. Analysis of IVDK data 1996–200910.1111/j.1365-2133.2011.10253.x ↗
24. Toxicology of Sorbic Acid and sorbates10.1080/02652039009373932 ↗
25. Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate10.1080/10915810152630729 ↗
26. Ex vivo human skin permeation of methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI)10.1007/s00204-017-1978-x ↗
27. Skin irritation potential of cosmetic preservatives: An exposure-relevant study10.1111/jocd.13502 ↗
28. Use of 2% 2-phenoxyethanol and 0.1% octenidine as antiseptic in premature newborn infants of 23–26 weeks gestation10.1053/jhin.2002.1249 ↗
29. Physical properties of parabens and their mixtures: Solubility in water, thermal behavior, and crystal structures10.1021/js9900452 ↗
30. The health controversies of parabens
31. European Commission (2014). Commission Regulation (EU) No 1004/2014 of 18 September 2014 Amending Annex V to Regulation (EC) No 1223/2009 of the European Parliament and of the Council on Cosmetic Products; 1004/2014, European Commission.
32. Stroppel, L., Schultz-Fademrecht, T., Cebulla, M., Blech, M., Marhöfer, R.J., Selzer, P.M., and Garidel, P. (2023). Antimicrobial Preservatives for Protein and Peptide Formulations: An Overview. Pharmaceutics, 563.10.3390/pharmaceutics15020563 ↗
33. Pentanol and Benzyl Alcohol Attack Bacterial Surface Structures Differently10.1128/AEM.02515-15 ↗