Automated Brain Tumor Identification in Biomedical Radiology Images: A Multi-Model Ensemble Deep Learning Approach
Source abstract
Abstract
Brain tumors (BT) represent a severe and potentially life-threatening cancer. Failing to promptly diagnose these tumors can significantly shorten a person’s life. Therefore, early and accurate detection of brain tumors is essential, allowing for appropriate treatment and improving the chances of a patient’s survival. Due to the different characteristics and data limitations of brain tumors is challenging problems to classify the three different types of brain tumors. A convolutional neural networks (CNNs) learning algorithm integrated with data augmentation techniques was used to improve the model performance. CNNs have been extensively utilized in identifying brain tumors through the analysis of Magnetic Resonance Imaging (MRI) images The primary aim of this research is to propose a novel method that achieves exceptionally high accuracy in classifying the three distinct types of brain tumors. This paper proposed a novel Stack Ensemble Transfer Learning model called “SETL_BMRI”, which can recognize brain tumors in MRI images with elevated accuracy. The SETL_BMRI model incorporates two pre-trained models, AlexNet and VGG19, to improve its ability to generalize. Stacking combined outputs from these models significantly improved the accuracy of brain tumor detection as compared to individual models. The model’s effectiveness is evaluated using a public brain MRI dataset available on Kaggle, containing images of three types of brain tumors (meningioma, glioma, and pituitary). The experimental findings showcase the robustness of the SETL_BMRI model, achieving an overall classification accuracy of 98.70%. Additionally, it delivers an average precision, recall, and F1-score of 98.75%, 98.6%, and 98.75%, respectively. The evaluation metric values of the proposed solution indicate that it effectively contributed to previous research in terms of achieving high detection accuracy.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Brain Tumor Detection and Classification · Advanced Neural Network Applications · AI in cancer detection
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Software Engineering, Sir Syed University of Engineering & Technology, Karachi 75300, Pakistan
Computer Science Department, Institute of Business Management (IoBM), Karachi 75190, Pakistan
College of Education, Jazan University, Jazan 82817, Saudi Arabia
E-Learning Center, Jazan University, Jazan 82817, Saudi Arabia
Funding
Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia
References (58)
Show source-provided references
1. Brain Tumour Classification Using Two-Tier Classifier with Adaptive Segmentation Technique10.1049/iet-cvi.2014.0193 ↗
2. An Introduction to Machine Learning10.1002/cpt.1796 ↗
3. A Hybrid Approach of Using Symmetry Technique for Brain Tumor Segmentation10.1155/2014/712783 ↗
4. Tumors Metastatic to the Pituitary Gland: Case Report and Literature Review10.1210/jc.2003-030395 ↗
5. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: A Summary10.1007/s00401-016-1545-1 ↗
6. A Survey on Brain Tumor Detection Techniques for MR Images10.1007/s11042-020-08898-3 ↗
7. Multi-Grade Brain Tumor Classification Using Deep CNN with Extensive Data Augmentation10.1016/j.jocs.2018.12.003 ↗
8. A Deep Learning-Based Framework for Automatic Brain Tumors Classification Using Transfer Learning10.1007/s00034-019-01246-3 ↗
9. Automatic Tumor Segmentation with Deep Convolutional Neural Networks for Radiotherapy Applications10.1007/s11063-017-9759-3 ↗
10. Deep Learning Based Brain Tumor Segmentation: Recent Updates10.1007/978-981-19-1122-4_42 ↗
11. Asad, R., Rehman, S.U., Imran, A., Li, J., Almuhaimeed, A., and Alzahrani, A. (2023). Computer-Aided Early Melanoma Brain-Tumor Detection Using Deep-Learning Approach. Biomedicines, 11.10.3390/biomedicines11010184 ↗
12. Özkaraca, O., Bağrıaçık, O.İ., Gürüler, H., Khan, F., Hussain, J., Khan, J., and Laila, U.e. (2023). Multiple Brain Tumor Classification with Dense CNN Architecture Using Brain MRI Images. Life, 13.10.3390/life13020349 ↗
13. Meena, S.D., Bulusu, S.V., Siddharth, V.S., Reddy, S.P., and Sheela, J. (2023). Brain Tumor Classification Using Transfer Learning, CRC Press.10.1201/9781003265436-9 ↗
14. Raza, A., Ayub, H., Khan, J.A., Ahmad, I., Salama, A.S., Daradkeh, Y.I., Javeed, D., Ur Rehman, A., and Hamam, H. (2022). A Hybrid Deep Learning-Based Approach for Brain Tumor Classification. Electronics, 11.10.3390/electronics11071146 ↗
15. Iman, M., Arabnia, H.R., and Rasheed, K. (2023). A Review of Deep Transfer Learning and Recent Advancements. Technologies, 11.10.3390/technologies11020040 ↗
16. (2023, July 30). Kaggle Official Web Page. Brain Tumor MRI Dataset. Available online: https://www.kaggle.com/datasets/masoudnickparvar/brain-tumor-mri-dataset.
17. Robust real-time polyp detection system design based on YOLO algorithms by optimizing activation functions and hyper-parameters with artificial bee colony (ABC)10.1016/j.eswa.2023.119741 ↗
18. MRI brain tumor detection using deep learning and machine learning approaches10.1016/j.measen.2024.101026 ↗
19. Albakri, A., and Alqahtani, Y.M. (2023). Internet of Medical Things with a Blockchain-Assisted Smart Healthcare System Using Metaheuristics with a Deep Learning Model. Appl. Sci., 13.10.3390/app13106108 ↗
20. A Novel Hybrid Deep Learning Model for Metastatic Cancer Detection10.1155/2022/8141530 ↗
21. Brain tumor classification in MRI image using convolutional neural network10.3934/mbe.2020328 ↗
22. Brain Tumor Detection and Classification Using Machine Learning: A Comprehensive Survey10.1007/s40747-021-00563-y ↗
23. Minarno, A.E., Mandiri, M.H.C., Munarko, Y., and Hariyady, H. (2021). Convolutional Neural Network with Hyperparameter Tuning for Brain Tumor Classification. Kinet. Game Technol. Inf. Syst. Comput. Netw. Comput. Electron. Control, 6.10.22219/kinetik.v6i2.1219 ↗
24. BrainMRNet: Brain Tumor Detection Using Magnetic Resonance Images with a Novel Convolutional Neural Network Model10.1016/j.mehy.2019.109531 ↗
25. An Integrated Design of Particle Swarm Optimization (PSO) with Fusion of Features for Detection of Brain Tumor10.1016/j.patrec.2019.11.017 ↗
26. Rajak, P., Jangde, A.S., and Gupta, G.P. (2023). Convergence of Big Data Technologies and Computational Intelligent Techniques, IGI Global.
27. Habiba, S.U., Islam, M.K., Nahar, L., Tasnim, F., Hossain, M.S., and Andersson, K. (2022, January 27–28). Brain-DeepNet: A Deep Learning Based Classifier for Brain Tumor Detection and Classification. Proceedings of the International Conference on Intelligent Computing & Optimization, Hua Hin, Thailand.10.1007/978-3-031-19958-5_52 ↗
28. Deep learning-based approaches for robust classification of cervical cancer10.1007/s00521-023-08757-w ↗
29. Gradient-Based Learning Applied to Document Recognition10.1109/5.726791 ↗
30. Parameshachari, B.D., and Sunil Kumar, D.S. (2022, January 16–17). SVM Based Brain Tumor Detection and Classification System. Proceedings of the 2022 IEEE 2nd Mysore Sub Section International Conference (MysuruCon), Mysuru, India.
31. Engstrom, L., Tran, B., Tsipras, D., Schmidt, L., and Madry, A. (2018). A Rotation and a Translation Suffice: Fooling CNNs with Simple Transformations. arXiv.
32. Goodfellow, I., Pouget-Abadie, J., Mirza, M., Xu, B., Warde-Farley, D., Ozair, S., Courville, A., and Bengio, Y. (2014, January 8–13). Generative Adversarial Nets. Proceedings of the Advances in Neural Information Processing Systems 27, Montreal, QC, Canada.
33. Combining Optimal Wavelet Statistical Texture and Recurrent Neural Network for Tumour Detection and Classification over MRI10.1007/s11042-020-08643-w ↗
34. Saeedi, S., Rezayi, S., Keshavarz, H., and Niakan Kalhori, S.R. (2023). MRI-Based Brain Tumor Detection Using Convolutional Deep Learning Methods and Chosen Machine Learning Techniques. BMC Med. Inform. Decis. Mak., 23.10.1186/s12911-023-02114-6 ↗
35. MRI Brain Tumor Detection and Classification Using Parallel Deep Convolutional Neural Networks10.1016/j.measen.2023.100694 ↗
36. Human Brain Tumor Classification and Segmentation Using CNN10.1007/s11042-022-13713-2 ↗
37. Kurdi, S.Z., Ali, M.H., Jaber, M.M., Saba, T., Rehman, A., and Damaševičius, R. (2023). Brain Tumor Classification Using Meta-Heuristic Optimized Convolutional Neural Networks. J. Pers. Med., 13.10.3390/jpm13020181 ↗
38. Analysis of MRI Brain Tumor Images Using Deep Learning Techniques10.1007/s00500-023-07921-7 ↗
39. Brain Tumor Image Generation Using an Aggregation of GAN Models with Style Transfer10.1038/s41598-022-12646-y ↗
40. Accurate Brain Tumor Detection Using Deep Convolutional Neural Network10.1016/j.csbj.2022.08.039 ↗
41. Automatic Brain Tumor Detection Using CNN Transfer Learning Approach10.1007/s11517-023-02820-3 ↗
42. A Systematic Approach for MRI Brain Tumor Localization and Segmentation Using Deep Learning and Active Contouring10.1155/2021/6695108 ↗
43. Ensemble of keyword extraction methods and classifiers in text classification10.1016/j.eswa.2016.03.045 ↗
44. A hybrid ensemble pruning approach based on consensus clustering and multi-objective evolutionary algorithm for sentiment classification10.1016/j.ipm.2017.02.008 ↗
45. Theory of Deep Convolutional Neural Networks: Down sampling10.1016/j.neunet.2020.01.018 ↗
46. A Hybrid Method for Heartbeat Classification via Convolutional Neural Networks, Multilayer Perceptron, and Focal Loss10.7717/peerj-cs.324 ↗
47. Efficient Densely Connected Convolutional Neural Networks10.1016/j.patcog.2020.107610 ↗
48. End-to-End Acoustic Modeling Using Convolutional Neural Networks for HMM-Based Automatic Speech Recognition10.1016/j.specom.2019.01.004 ↗
49. Scherer, D., Müller, A., and Behnke, S. (2010). Artificial Neural Networks—ICANN 2010, Proceedings of the 20th International Conference, Thessaloniki, Greece, 15–18 September 2010, Springer.
50. Imagenet classification with deep convolutional neural networks10.1145/3065386 ↗
51. Han, X., Zhong, Y., Cao, L., and Zhang, L. (2017). Pre-Trained Alexnet Architecture with Pyramid Pooling and Supervision for High Spatial Resolution Remote Sensing Image Scene Classification. Remote Sens., 9.10.3390/rs9080848 ↗
52. 3D Variational Brain Tumor Segmentation Using Dirichlet Priors on a Clustered Feature Set10.1007/s11548-011-0649-2 ↗
53. Comparison of deep learning approaches for multi-label chest X-ray classification10.1038/s41598-019-42294-8 ↗
54. Laila, U.E., Mahboob, K., Khan, A.W., Khan, F., and Taekeun, W. (2022). An Ensemble Approach to Predict Early-Stage Diabetes Risk Using Machine Learning: An Empirical Study. Sensors, 22.10.3390/s22145247 ↗
55. A novel approach for breast cancer detection using optimized ensemble learning framework and XAI10.1016/j.imavis.2024.104910 ↗
56. Harish, P., and Baskar, S. (2020). WITHDRAWN: MRI Based Detection and Classification of Brain Tumor Using Enhanced Faster R-CNN and Alex Net Model, Elsevier.10.1016/j.matpr.2020.11.495 ↗
57. Wong, S.C., Gatt, A., Stamatescu, V., and McDonnell, M.D. (2016—2, January 30). Understanding Data Augmentation for Classification: When to Warp?. Proceedings of the 2016 International Conference on Digital Image Computing: Techniques and Applications (DICTA), Gold Coast, QLD, Australia.10.1109/DICTA.2016.7797091 ↗
58. Garcea, F., Serra, A., Lamberti, F., and Morra, L. (2023). Data augmentation for medical imaging: A systematic literature review. Comput. Biol. Med., 152.10.1016/j.compbiomed.2022.106391 ↗