β-Glucans from Yeast—Immunomodulators from Novel Waste Resources
Source abstract
Abstract
β-glucans are a large class of complex polysaccharides with bioactive properties, including immune modulation. Natural sources of these compounds include yeast, oats, barley, mushrooms, and algae. Yeast is abundant in various processes, including fermentation, and they are often discarded as waste products. The production of biomolecules from waste resources is a growing trend worldwide with novel waste resources being constantly identified. Yeast-derived β-glucans may assist the host’s defence against infections by influencing neutrophil and macrophage inflammatory and antibacterial activities. β-glucans were long regarded as an essential anti-cancer therapy and were licensed in Japan as immune-adjuvant therapy for cancer in 1980 and new mechanisms of action of these molecules are constantly emerging. This paper outlines yeast β-glucans’ immune-modulatory and anti-cancer effects, production and extraction, and their availability in waste streams.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Polysaccharides and Plant Cell Walls · Immune responses and vaccinations · Probiotics and Fermented Foods
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Life and Physical Sciences, Midlands Campus, Technological University of the Shannon, N37 HD68 Athlone, Ireland
Department of Emergency and Intensive Care, San Gerardo University Hospital, ASST Monza, 20900 Monza, Italy
School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy
Materials Research Institute, Midlands Campus, Technological University of the Shannon, N37 HD68 Athlone, Ireland
LIFE—Health and Biosciences Research Institute, Midwest Campus, Technological University of the Shannon, V94 EC5T Limerick, Ireland
Shannon Applied Biotechnology Centre, Department of Applied Science, Faculty of Applied Sciences and Technology, Moylish Campus, Technological University of the Shannon, Midlands Midwest, Moylish, V94 EC5T Limerick, Ireland
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