journal article·2021-11-27Open access

Anticancer Effects of Seaweed-Derived Bioactive Compounds

Heesu Lee, Baskar Selvaraj, Jae Wook Lee

Applied Sciences· Volume 11· Issue 23

Abstract

Cancer remains a major life-threatening disease worldwide. The development of anticancer drugs using natural products obtained from marine organisms has been proposed as an alternative approach. Seaweeds are the mainstay of marine ecosystems; therefore, they are highly enriched with diverse bioactive compounds. In the past decade, a vast number of natural compounds, such as polysaccharides, polyphenols, carotenoids, and terpenoids, have been isolated from seaweeds. Seaweeds have bioactive compounds that show cytotoxicity in various cancer cell lines. These compounds prevent tumor growth by inducing apoptotic cell death and arrest growth by interfering with different kinases and cell cycle pathways. This review discussed the anticancer properties of various bioactive compounds isolated from different types of seaweeds and their therapeutic potential against cancers.
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Research context

OpenAlex topics: Seaweed-derived Bioactive Compounds · Protein Hydrolysis and Bioactive Peptides · Algal biology and biofuel production

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Anatomy, College of Dentistry, Gangneung Wonju National University, Gangneung 25457, Korea

Natural Product Research Center, Institute of Natural Product, Korea Institute of Science and Technology, Gangneung 25451, Korea

Convergence Research Center of Dementia, Brain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea

Division of Bio-Medical Science & Technology, University of Science and Technology, Daejun 34113, Korea

Funding

National Research Foundation of Korea · KIST Institutional Program · National Research Council of Science & Technology (NST)

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