Glucose Isomerase: Functions, Structures, and Applications
Source abstract
Abstract
Glucose isomerase (GI, also known as xylose isomerase) reversibly isomerizes D-glucose and D-xylose to D-fructose and D-xylulose, respectively. GI plays an important role in sugar metabolism, fulfilling nutritional requirements in bacteria. In addition, GI is an important industrial enzyme for the production of high-fructose corn syrup and bioethanol. This review introduces the functions, structure, and applications of GI, in addition to presenting updated information on the characteristics of newly discovered GIs and structural information regarding the metal-binding active site of GI and its interaction with the inhibitor xylitol. This review provides an overview of recent advancements in the characterization and engineering of GI, as well as its industrial applications, and will help to guide future research in this field.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Diet, Metabolism, and Disease · Pancreatic function and diabetes · Plant nutrient uptake and metabolism
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Life Science, Pohang University of Science and Technology, Pohang 37673, Korea
POSTECH Biotech Center, Pohang University of Science and Technology, Pohang 37673, Korea
Funding
National Research Foundation of Korea
References (78)
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