Recent Advances in Cellulose-Based Structures as the Wound-Healing Biomaterials: A Clinically Oriented Review
Source abstract
Abstract
Application of wound-healing/dressing biomaterials is amongst the most promising approaches for wound repair through protection from pathogen invasion/contamination, maintaining moisture, absorbing exudates, modulating inflammation, and facilitating the healing process. A wide range of materials are used to fabricate wound-healing/dressing biomaterials. Active wound-healing/dressings are next-generation alternatives for passive biomaterials, which provide a physical barrier and induce different biological activities, such as antibacterial, antioxidant, and proliferative effects. Cellulose-based biomaterials are particularly promising due to their tunable physical, chemical, mechanical, and biological properties, accessibility, low cost, and biocompatibility. A thorough description and analysis of wound-healing/dressing structures fabricated from cellulose-based biomaterials is discussed in this review. We emphasize and highlight the fabrication methods, applied bioactive molecules, and discuss the obtained results from in vitro and in vivo models of cellulose-based wound-healing biomaterials. This review paper revealed that cellulose-based biomaterials have promising potential as the wound-dressing/healing materials and can be integrated with various bioactive agents. Overall, cellulose-based biomaterials are shown to be effective and sophisticated structures for delivery applications, safe and multi-customizable dressings, or grafts for wound-healing applications.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Wound Healing and Treatments · Advanced Cellulose Research Studies · Electrospun Nanofibers in Biomedical Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran 19987-11111, Iran
Department of Biomedical Engineering, Rochester Institute of Technology, 160 Lomb Memorial Drive, Rochester, NY 14623, USA
Microsystems Engineering, Rochester Institute of Technology, Rochester, NY 14623, USA
Department of Biology, Varamin Pishva Branch, Islamic Azad University, Varamin 16517-16151, Iran
Department of Biology, Faculty of Science and Research, Islamic Azad University, Tehran 19558-65143, Iran
Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC V6T 1X7, Canada
Brain Research Centre, University of British Columbia, Vancouver, BC V6T 1X7, Canada
Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah 67158-47141, Iran
Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah 67158-47141, Iran
Radiation Biology Research Center, Iran University of Medical Sciences, Tehran 14496-14535, Iran
Department of Medical Biotechnology, Faculty of Paramedicine, Guilan University of Medical Sciences, Rasht 44771-66595, Iran
Université Clermont Auvergne, Clermont Auvergne INP, CNRS, Institut Pascal, 63000 Clermont-Ferrand, France
Institut Universitaire de France (IUF), 1 rue Descartes, 75005 Paris, France
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