journal article·2023-01-22Open access

Smart Healthcare Applications over 5G Networks: A Systematic Review

Angélica M. Peralta-Ochoa, Pedro A. Chaca-Asmal, Luis F. Guerrero-Vásquez, Jorge O. Ordoñez-Ordoñez, Edwin J. Coronel-González

Applied Sciences· Volume 13· Issue 3

Abstract

Provisioning of health services such as care, monitoring, and remote surgery is being improved thanks to fifth-generation cellular technology (5G). As 5G expands globally, more smart healthcare applications have been developed due to its extensive eMBB (Enhanced Mobile Broadband) and URLLC (Ultra-Reliable Low Latency Communications) features that can be used to generate healthcare systems that allow minimizing the face-to-face assistance of patients at hospital centers. This powerful network provides high transmission speeds, ultra-low latency, and a network capacity greater than that of 4G. Fifth-generation cellular technology is expected to be a means to provide excellent quality of medical care, through its technological provision to the use of IoMT (Internet of Medical Things) devices. Due to the numerous contributions in research on this topic, it is necessary to develop a review that provides an orderly perspective on research trends and niches for researchers to use as a starting point for their work. In this context, this article presents a systematic review based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), with article selection based on inclusion and exclusion criteria that avoid bias. This research was based on research questions that were answered from the included works. These questions focus on technical characteristics, health benefits, and security protocols necessary for the development of smart healthcare applications. We have identified that a high percentage of existing works in the literature are proposals (56.81%, n = 25) and theoretical studies (22.73%, n = 10); few implementations (15.91%, n = 7) and prototypes (4.55%, n = 2) exist, due to the limited global deployment of 5G. However, the panorama looks promising based on proposals and future work that these technological systems allow, all based on improving healthcare for people.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Wireless Body Area Networks · IoT and Edge/Fog Computing · Mobile Health and mHealth Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Electronic Engineering School, Universidad Politécnica Salesiana, Cuenca 010102, Ecuador

GI-IATa, UNESCO Chair on Support Technologies for Educational Inclusion, Universidad Politécnica Salesiana, Cuenca 010102, Ecuador

Funding

Universidad Politécnica Salesiana, Cuenca-Ecuador

References (67)

Show source-provided references
1. Neha, G., Juneja, P.K., Sharma, S., and Garg, U. (2021, January 6–8). Future Aspect of 5G-IoT Architecture in Smart Healthcare System. Proceedings of the 2021 5th International Conference on Intelligent Computing and Control Systems (ICICCS), Madurai, India.
2. Magsi, H., Sodhro, A.H., Chachar, F.A., Abro, S.A.K., Sodhro, G.H., and Pirbhulal, S. (2018, January 3–4). Evolution of 5G in Internet of medical things. Proceedings of the 2018 International Conference on Computing, Mathematics and Engineering Technologies (iCoMET), Sukkur, Pakistan.10.1109/ICOMET.2018.8346428 ↗
3. Kapassa, E., Touloupou, M., Mavrogiorgou, A., Kiourtis, A., Giannouli, D., Katsigianni, K., and Kyriazis, D. (2019, January 22–25). An Innovative eHealth System Powered By 5G Network Slicing. Proceedings of the 2019 Sixth International Conference on Internet of Things: Systems, Management and Security (IOTSMS), Granada, Spain.10.1109/IOTSMS48152.2019.8939266 ↗
4. 5G in healthcare: How fast will be the transformation?10.1007/s11845-020-02329-w ↗
5. Vergütz, A., Prates, N.G., Henrique Schwengber, B., Santos, A., and Nogueira, M. (2020). An Architecture for the Performance Management of Smart Healthcare Applications. Sensors, 20.10.3390/s20195566 ↗
6. An Anonymous Key Distribution Scheme for Group Healthcare Services in 5G-Enabled Multi-Server Environments10.1109/ACCESS.2021.3070641 ↗
7. Soldani, D., Fadini, F., Rasanen, H., Duran, J., Niemela, T., Chandramouli, D., Hoglund, T., Doppler, K., Himanen, T., and Laiho, J. (2017, January 4–7). 5G Mobile Systems for Healthcare. Proceedings of the 2017 IEEE 85th Vehicular Technology Conference (VTC Spring), Sydney, Australia.10.1109/VTCSpring.2017.8108602 ↗
8. Latif, S., Qadir, J., Farooq, S., and Imran, M.A. (2017). How 5g wireless (and concomitant technologies) will revolutionize healthcare?. Future Internet, 9.10.3390/fi9040093 ↗
9. Selem, E., Fatehy, M., and El-Kader, S.M.A. (2019, January 17–20). E-Health applications over 5G networks: Challenges and state of the art. Proceedings of the 2019 6th International Conference on Advanced Control Circuits and Systems (ACCS) 2019 5th International Conference on New Paradigms in Electronics information Technology (PEIT), Hurghada, Egypt.10.1109/ACCS-PEIT48329.2019.9062841 ↗
10. Telemedicine: Patient-Provider Clinical Engagement During the COVID-19 Pandemic and Beyond10.1007/s11605-020-04623-5 ↗
11. Zhang, C. (2021, October 13). 5G Aplications Help and China Fight against COVID-19. Available online: http://www.caict.ac.cn/english/research/covid19/study/202004/t20200426_280331.html.
12. The role of fifth-generation mobile technology in prehospital emergency care: An opportunity to support paramedics10.1016/j.hlpt.2020.01.002 ↗
13. The role of 5G for digital healthcare against COVID-19 pandemic: Opportunities and challenges10.1016/j.icte.2020.10.002 ↗
14. Ahad, A., Tahir, M., Aman Sheikh, M., Ahmed, K.I., Mughees, A., and Numani, A. (2020). Technologies Trend towards 5G Network for Smart Health-Care Using IoT: A Review. Sensors, 20.10.3390/s20144047 ↗
15. Fifth Generation Cellular Networks and Neurosurgery: A Narrative Review10.1016/j.wneu.2021.09.054 ↗
16. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement10.7326/0003-4819-151-4-200908180-00135 ↗
17. M-Health Solutions Using 5G Networks and M2M Communications10.1109/MITP.2016.52 ↗
18. Jusak, J., Pratikno, H., and Putra, V.H. (2016, January 8–10). Internet of Medical Things for cardiac monitoring: Paving the way to 5G mobile networks. Proceedings of the 2016 IEEE International Conference on Communication, Networks and Satellite (COMNETSAT), Surabaya, Indonesia.10.1109/COMNETSAT.2016.7907420 ↗
19. Kyriacou, E., Christofides, S., and Pattichis, C.S. (April, January 31). Towards 5G Health for Medical Video Streaming over Small Cells. Proceedings of the XIV Mediterranean Conference on Medical and Biological Engineering and Computing 2016, Paphos, Cyprus.10.1007/978-3-319-32703-7 ↗
20. Smart Mobile Healthcare System based on WBSN and 5G
21. An architecture and protocol for smart continuous eHealth monitoring using 5G10.1016/j.comnet.2017.05.018 ↗
22. Emotion-Aware Connected Healthcare Big Data Towards 5G10.1109/JIOT.2017.2772959 ↗
23. Smartphone-Powered Electrochemical Biosensing Dongle for Emerging Medical IoTs Application10.1109/TII.2017.2777145 ↗
24. Fang, D., and Ye, F. (2018, January 20–24). Identity Management Framework for E-Health Systems over 5G Networks. Proceedings of the 2018 IEEE International Conference on Communications (ICC), Kansas City, MO, USA.10.1109/ICC.2018.8422885 ↗
25. Deshpande, A., Unal, A., Passi, K., Singh, D., Nayak, M., Patel, B., and Pathan, S. (2017, January 18–19). Advanced LTE (5G) in Medical IOT-Research, Future and Scope. Proceedings of the Smart Trends in Information Technology and Computer Communications, Pune, India.10.1007/978-981-13-1423-0 ↗
26. Mohanta, B., Das, P., and Patnaik, S. (2019, January 27–28). Healthcare 5.0: A Paradigm Shift in Digital Healthcare System Using Artificial Intelligence, IOT and 5G Communication. Proceedings of the 2019 International Conference on Applied Machine Learning (ICAML), Bhubaneswar, India.10.1109/ICAML48257.2019.00044 ↗
27. Zhang, D., Zhang, T., Zhai, Y., Rodrigues, J.J.P.C., Zhang, D., Wen, Z., Yu, K., and Sato, T. (2019, January 4–6). 5G-Enabled Health Systems: Solutions, Challenges and Future Research Trends. Proceedings of the 2019 ITU Kaleidoscope: ICT for Health: Networks, Standards and Innovation (ITU K), Atlanta, GA, USA.10.23919/ITUK48006.2019.8995906 ↗
28. Mamun, M.I., Rahman, A., Khaleque, M.A., Hamid, M.A., and Mridha, M.F. (2019, January 22–25). AutiLife: A Healthcare Monitoring System for Autism Center in 5G Cellular Network using Machine Learning Approach. Proceedings of the 2019 IEEE 17th International Conference on Industrial Informatics (INDIN), Helsinki-Espoo, Finland.10.1109/INDIN41052.2019.8972179 ↗
29. Tactile-Internet-Based Telesurgery System for Healthcare 4.0: An Architecture, Research Challenges, and Future Directions10.1109/MNET.001.1900063 ↗
30. Imran, M.A., Sambo, Y.A., and Abbasi, Q.H. (2019). Enabling 5G Communication Systems to Support Vertical Industries, Wiley.10.1002/9781119515579 ↗
31. Usman, M., Philip, N., and Politis, C. (2019, January 9–13). 5G enabled mobile healthcare for ambulances. Proceedings of the 2019 IEEE Globecom Workshops (GC Wkshps), Waikoloa, HI, USA.10.1109/GCWkshps45667.2019.9024584 ↗
32. Post-surgical fall detection by exploiting the 5 G C-Band technology for eHealth paradigm10.1016/j.asoc.2019.105537 ↗
33. Morosi, S., Jayousi, S., Mucchi, L., Peinetti, F., Mastrantonio, L., Fioravanti, G., Giacomini, A., Fratini, A., Padiglione, F., and De Lucia, F. (2019, January 2–3). Medical Tele-Monitoring and Tele-Assistance for Diabetics Patients by Means of 5G Cellular Networks. Proceedings of the EAI International Conference on Body Area Networks, Florence, Italy.10.1007/978-3-030-34833-5_7 ↗
34. Padmashree, T., and Nayak, S.S. (2020, January 7–9). 5G Technology for E-Health. Proceedings of the 2020 Fourth International Conference on I-SMAC (IoT in Social, Mobile, Analytics and Cloud) (I-SMAC), Palladam, India.
35. Tsoulchas, V., Tsolis, N., Zoumi, E., Skondras, E., and Vergados, D.D. (2020, January 15–17). Health Monitoring of People with Diabetes using IoT and 5G Wireless Network Infrastructures. Proceedings of the 2020 11th International Conference on Information, Intelligence, Systems and Applications (IISA), Piraeus, Greece.10.1109/IISA50023.2020.9284388 ↗
36. 5G Enabled Tactile Internet for Tele-Robotic Surgery10.1016/j.procs.2020.04.284 ↗
37. Future 5g network based smart hospitals: Hybrid detection technique for latency improvement10.1109/ACCESS.2020.3017625 ↗
38. 5G ultra-remote robot-assisted laparoscopic surgery in China10.1007/s00464-020-07823-x ↗
39. The Role of Health Technology and Informatics in a Global Public Health Emergency: Practices and Implications From the COVID-19 Pandemic10.2196/19866 ↗
40. Khorashadizadeh, S., Ikuesan, A.R., and Kebande, V.R. (2019, January 22–23). Generic 5g infrastructure for iot ecosystem. Proceedings of the International Conference of Reliable Information and Communication Technology, Johor, Malaysia.10.1007/978-3-030-33582-3_43 ↗
41. A Security Awareness and Protection System for 5G Smart Healthcare Based on Zero-Trust Architecture10.1109/JIOT.2020.3041042 ↗
42. A Home Telemedicine System for Continuous Respiratory Monitoring10.1109/JBHI.2020.3012621 ↗
43. 5G-Network-Enabled Smart Ambulance: Architecture, Application, and Evaluation10.1109/MNET.011.2000014 ↗
44. Sports and health big data system based on 5G network and Internet of Things system10.1016/j.micpro.2020.103363 ↗
45. Optimal deep learning approaches and healthcare big data analytics for mobile networks toward 5G10.1016/j.compeleceng.2021.107376 ↗
46. Highly efficient key agreement for remote patient monitoring in MEC-enabled 5G networks10.1007/s11227-020-03472-y ↗
47. Ensemble Learning Based Postpartum Hemorrhage Diagnosis for 5G Remote Healthcare10.1109/ACCESS.2021.3051215 ↗
48. Design and Implementation of 5G e-Health Systems: Technologies, Use Cases, and Future Challenges10.1109/MCOM.001.2100035 ↗
49. Lin, T.W., and Hsu, C.L. (2021). FAIDM for Medical Privacy Protection in 5G Telemedicine Systems. Appl. Sci., 11.10.3390/app11031155 ↗
50. Integration of 5G and Block-Chain Technologies in Smart Telemedicine Using IoT10.1155/2021/8814364 ↗
51. Application of 5G Technology to Conduct Real-Time Teleretinal Laser Photocoagulation for the Treatment of Diabetic Retinopathy10.1001/jamaophthalmol.2021.2312 ↗
52. 5G-enabled ultra-sensitive fluorescence sensor for proactive prognosis of COVID-1910.1016/j.bios.2021.113160 ↗
53. Lin, T.W., Hsu, C.L., Le, T.V., Lu, C.F., and Huang, B.Y. (2021). A Smartcard-Based User-Controlled Single Sign-On for Privacy Preservation in 5G-IoT Telemedicine Systems. Sensors, 21.10.3390/s21082880 ↗
54. Lightweight authentication protocol for e-health clouds in IoT-based applications through 5G technology10.1016/j.dcan.2020.06.003 ↗
55. Tang, Z., Hu, H., Xu, C., and Zhao, K. (2021). Exploring an Efficient Remote Biomedical Signal Monitoring Framework for Personal Health in the COVID-19 Pandemic. Int. J. Environ. Res. Public Health, 18.10.3390/ijerph18179037 ↗
56. Ying, S., and Yu, W. (2021, January 24–29). Application of 5G Technology in the Construction of Intelligent Health Management System. Proceedings of the International Conference on Human–Computer Interaction, Virtual Event.10.1007/978-3-030-78645-8_52 ↗
57. Seamless Health Monitoring Using 5G NR for Internet of Medical Things10.1007/s11277-021-08730-7 ↗
58. Application of a Robotic Tele-Echography System for COVID-19 Pneumonia10.1002/jum.15406 ↗
59. A 5G-powered robot-assisted teleultrasound diagnostic system in an intensive care unit10.1186/s13054-021-03563-z ↗
60. Talukder, A., and Haas, R. (2021, January 21–25). AIoT: AI meets IoT and Web in Smart Healthcare. Proceedings of the 13th ACM Web Science Conference 2021, Virtual Event, UK.10.1145/3462741.3466650 ↗
61. A systematic review of IoT in healthcare: Applications, techniques, and trends10.1016/j.jnca.2021.103164 ↗
62. Guerrero-Vásquez, L.F., López-Nores, M., Pazos-Arias, J.J., Robles-Bykbaev, V.E., Bustamante-Cacao, K.C., Jara-Quito, H.J., Bravo-Torres, J.F., and Campoverde-Jara, P.X. (2022). Review Journal of Autism and Developmental Disorders, Springer.
63. Smart cities and public health: A systematic review10.1016/j.procs.2019.12.214 ↗
64. Pacheco Rocha, N., Dias, A., Santinha, G., Rodrigues, M., Queirós, A., and Rodrigues, C. (2019). Smart Cities and Healthcare: A Systematic Review. Technologies, 7.10.3390/technologies7030058 ↗
65. Rocha, N.P., Bastardo, R., Pavão, J., Santinha, G., Rodrigues, M., Rodrigues, C., Queirós, A., and Dias, A. (2021). Smart Cities’ Applications to Facilitate the Mobility of Older Adults: A Systematic Review of the Literature. Appl. Sci., 11.10.3390/app11146395 ↗
66. Cortés (2021, December 09). Tendencias de Salud Digital 2022. Available online: https://www.conexiones365.com/nota/expo-med/innovacion/tendencias-salud-digital-2022.
67. WHO (2021, December 10). La Oms Publica El Primer Informe Mundial Sobre Inteligencia Artificial (IA) Aplicada a la Salud y Seis Principios Rectores Relativos a su Concepción Y Utilización. Available online: https://www.who.int/es/news/item/28-06-2021-who-issues-first-global-report-on-ai-in-health-and-six-guiding-principles-for-its-design-and-use.