Comparison of Iron Oxide Nanoparticles in Photothermia and Magnetic Hyperthermia: Effects of Clustering and Silica Encapsulation on Nanoparticles’ Heating Yield
Source abstract
Abstract
Photothermal therapy is gathering momentum. In order to assess the effects of the encapsulation of individual or clustered superparamagnetic iron oxide nanoparticles (SPIONs) on nanoparticle light-to-heat conversion, we designed and tested individual and clustered SPIONs encapsulated within a silica shell. Our study compared both photothermia and magnetic hyperthermia, and it involved individual SPIONs as well as silica-encapsulated individual and clustered SPIONs. While, as expected, SPION clustering reduced heat generation in magnetic hyperthermia, the silica shell improved SPION heating in photothermia.
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Research context
OpenAlex topics: Nanoparticle-Based Drug Delivery · Nanofluid Flow and Heat Transfer · Photoacoustic and Ultrasonic Imaging
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department for Materials Synthesis, Jožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia
Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia
Laboratoire Matière et Systèmes Complexes (MSC), UMR 7057, CNRS and Université Paris Diderot, Bâtiment Condorcet, 10 rue Alice Domon et Léonie Duquet, 75205 Paris, France
Sorbonne Université, CNRS UMR 8234, PHysico-chimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), F-75005 Paris, France
Institute of Pharmacology and Structural Biology, 205 Route de Narbonne, 31400 Toulouse, France
Funding
Javna Agencija za Raziskovalno Dejavnost RS
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