journal article·2020-09-28Open access

AI-Based Stroke Disease Prediction System Using Real-Time Electromyography Signals

Jaehak Yu, Sejin Park, Soon-Hyun Kwon, Chee Meng Benjamin Ho, Cheol-Sig Pyo, Hansung Lee

Applied Sciences· Volume 10· Issue 19

Abstract

Stroke is a leading cause of disabilities in adults and the elderly which can result in numerous social or economic difficulties. If left untreated, stroke can lead to death. In most cases, patients with stroke have been observed to have abnormal bio-signals (i.e., ECG). Therefore, if individuals are monitored and have their bio-signals measured and accurately assessed in real-time, they can receive appropriate treatment quickly. However, most diagnosis and prediction systems for stroke are image analysis tools such as CT or MRI, which are expensive and difficult to use for real-time diagnosis. In this paper, we developed a stroke prediction system that detects stroke using real-time bio-signals with artificial intelligence (AI). Both machine learning (Random Forest) and deep learning (Long Short-Term Memory) algorithms were used in our system. EMG (Electromyography) bio-signals were collected in real time from thighs and calves, after which the important features were extracted, and prediction models were developed based on everyday activities. Prediction accuracies of 90.38% for Random Forest and of 98.958% for LSTM were obtained for our proposed system. This system can be considered an alternative, low-cost, real-time diagnosis system that can obtain accurate stroke prediction and can potentially be used for other diseases such as heart disease.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Stroke Rehabilitation and Recovery · Artificial Intelligence in Healthcare · Acute Ischemic Stroke Management

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of KSB Convergence Research, Electronics and Telecommunications Research Institute (ETRI), Daejeon 34129, Korea

School of Computer Engineering, Youngsan University, 288 Junam-Ro, Yangsan, Gyeongnam 50510, Korea

Funding

Ministry of Science, ICT and Future Planning

References (55)

Show source-provided references
1. Deep learning for IoT Big data and streaming analytics: A survey10.1109/COMST.2018.2844341 ↗
2. Fourth industrial revolution for development: The relevance of Cloud federation in healthcare support10.1109/ACCESS.2019.2960615 ↗
3. The fourth industrial revolution (Industry 4.0): A social innovation perspective10.22215/timreview/1117 ↗
4. Lopes, N.V.M. (2020). AI, IoT, Big data, and technologies in digital economy with blockchain at sustainable work satisfaction to smart mankind: Access to 6th dimension of human rights. Smart Governance for Cities: Perspectives and Experiences, Springer. [2nd ed.].
5. Global, regional, and national burden of stroke, 1990-2016: A systematic analysis for the Global Burden of Disease Study 201610.1016/S1474-4422(19)30034-1 ↗
6. Automated segmentation and classification of brain stroke using expectation-maximization and random forest classifier10.1016/j.bbe.2019.04.004 ↗
7. Simple estimates of symptomatic intracranial hemorrhage risk and outcome after intravenous thrombolysis using age and stroke severity10.5853/jos.2016.01109 ↗
8. Traditional risk factors for stroke in East Asia10.5853/jos.2016.00885 ↗
9. Female-and male-specific risk factors for stroke: A systematic review and meta-analysis
10. Is atrial fibrillation a stroke risk factor or risk marker? An appraisal using the bradford hill framework for causality10.1016/j.hlc.2019.08.005 ↗
11. Centers for Disease Control and Prevention (2020, September 27). The Third National Health and Nutrition Examination Survey (NHANES III 1988-94) Reference Manuals and Reports, Available online: https://wwwn.cdc.gov/nchs/nhanes/nhanes3/ManualsAndReports.aspx.
12. Probability of stroke: A risk profile from the Framingham study
13. Stroke risk profile: Adjustment for antihypertensive medication: The Framingham Study
14. Framingham risk function overestimates risk of coronary heart disease in men and women from Germany-results from the MONICA Augsburg and the RPOCAM cohorts10.1016/S0195-668X(03)00081-2 ↗
15. Coronary heart disease incidence in northern and southern European populations: A reanalysis of the seven countries study for a European coronary risk chart10.1136/heart.84.3.238 ↗
16. Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese multi-provincial cohort study10.1001/jama.291.21.2591 ↗
17. Stroke risk prediction model: A risk profile from the Korean study10.1016/j.atherosclerosis.2007.05.014 ↗
18. Yu, J., Kim, D., Park, H., Chon, S., Cho, K., Kim, S., Yu, S., Park, S., and Hong, S. (2019, January 28–30). Semantic Analysis of NIH stroke scale using machine learning techniques. Proceedings of the 2019 International Conference on Platform Technology and Service (PlatCon), Jeju, Korea.10.1109/PlatCon.2019.8668961 ↗
19. Acute ischaemic stroke prediction from physiological time series patterns10.4066/AMJ.2013.1650 ↗
20. Sengupta, A., Rajan, V., Bhattacharya, S., and Sarma, G.R.K. (2016, January 16–20). A statistical model for stroke outcome prediction and treatment planning. Proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Orlando, FL, USA.10.1109/EMBC.2016.7591242 ↗
21. Statistics Korea (2020, September 27). The Cause of Death Statistics in Koreans. Available online: http://kostat.go.kr/portal/korea/kor_nw/1/6/2/index.board.
22. Retrospective assessment of initial stroke severity: Comparison of the NIH stroke scale and the Canadian neurological scale10.1161/01.STR.32.3.656 ↗
23. Prediction of functional outcome after stroke: Comparison of the orpington prognostic scale and the NIH stroke scale
24. The modified National Institutes of Health Stroke Scale: Its time has come10.1111/j.1747-4949.2009.00294.x ↗
25. Development of a stroke prediction model for Korean
26. Trialists’ Collaboration Antithrombotic (2002). Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. Br. Med. J. (BMJ), 324, 71–86.10.1136/bmj.324.7329.71 ↗
27. Latest perspectives on cigarette smoking and cardiovascular disease: The Framingham study
28. On the use and utility of the Weibull model in the analysis of survival data10.1016/S0197-2456(03)00072-2 ↗
29. Long-term risk of recurrent stroke after a first-ever stroke
30. Knowledge, health-promoting behaviors, and biological risks of recurrent stroke among stroke patients in Korea10.1111/jjns.12013 ↗
31. EEG in ischaemic stroke: Quantitative EEG can uniquely inform (sub-)acute prognoses and clinical management10.1016/j.clinph.2012.07.003 ↗
32. Constructing the prediction model for the risk of stroke in a Chinese population: Report from a cohort study in Taiwan10.1161/STROKEAHA.110.586222 ↗
33. Long sleep duration and risk of ischemic stroke and hemorrhagic stroke: The Kailuan prospective study10.1038/srep36861 ↗
34. Designing an artificial neural network model for the prediction of thrombo-embolic stroke
35. Evolving spiking neural networks for personalised modelling, classification and prediction of spatio-temporal patterns with a case study on stroke10.1016/j.neucom.2013.09.049 ↗
36. Singh, M.S., Choudhary, P., and Thongam, K. (2019, January 27–29). A Comparative Analysis for Various Stroke Prediction Techniques. Proceedings of the International Conference on Computer Vision and Image Processing (CVIP 2019), Jaipur, India.
37. Artificial neural network prediction of ischemic tissue fate in acute stroke imaging10.1038/jcbfm.2010.56 ↗
38. Prediction of stroke thrombolysis outcome using CT brain machine learning10.1016/j.nicl.2014.02.003 ↗
39. Khosla, A., Cao, Y., Lin, C.C.Y., Chiu, H.K., Hu, J., and Lee, H. (2010, January 24–28). An integrated machine learning approach to stroke prediction. Proceedings of the 16th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, Washington, DC, USA.10.1145/1835804.1835830 ↗
40. Prediction and control of stroke by data mining
41. Pascanu, R., Gulcehre, C., Cho, K., and Bengio, Y. (2013). How to construct deep recurrent neural networks. arXiv, Available online: https://arxiv.org/abs/1312.6026.
42. Long short-term memory10.1162/neco.1997.9.8.1735 ↗
43. Android malware detection based on system call sequences and LSTM10.1007/s11042-017-5104-0 ↗
44. MathWorks, Inc. (2020, September 27). Long Short-Term Memory Networks. Available online: https://www.https://www.mathworks.com/help/deeplearning/ug/long-short-term-memory-networks.html.
45. Chantamit, P., and Goyal, M. (2018, January 15–19). Long short-term memory recurrent neural network for stroke prediction. Proceedings of the International Conference on Machine Learning and Data Mining in Pattern Recognition (MLDM 2018), New York, NY, USA.
46. WHO (2020, September 27). ICD-10: International Statistical Classification of Disease and Related Health Tenth Revision. Available online: https://www.who.int/classifications/icd/ICD-10_2nd_ed_volume2.pdf.
47. Yu, Y., Parsi, B., Speier, W., Arnold, C., Lou, M., and Scalzo, F. (2019, January 13–17). LSTM Network for Prediction of Hemorrhagic Transformation in Acute Stroke. Proceedings of the International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2019), Shenzhen, China.10.1007/978-3-030-32251-9_20 ↗
48. Design of a concise and comprehensive protocol for post stroke neuromechanical assessment
49. Electromyographic biofeedback for neuromuscular reeducation in the hemiplegic stroke patient: A meta-analysis10.1016/0003-9993(93)90083-M ↗
50. A community-based fitness and mobility exercise program for older adults with chronic stroke: A randomized, controlled trial10.1111/j.1532-5415.2005.53521.x ↗
51. Accuracy of weightbearing estimation by stroke versus healthy subjects10.2466/pms.1991.72.3.935 ↗
52. An EMG-driven model to estimate muscle forces and joint moments in stroke patients10.1016/j.compbiomed.2009.09.002 ↗
53. A review of standing balance recovery from stroke10.1016/j.gaitpost.2004.10.002 ↗
54. Hall, M. (1998). Correlation-based Feature Selection for Machine Learning. [Ph.D. Thesis, Department of Computer Science, The University of Waikato].
55. Real-time cooling load forecasting using a hierarchical multi-class SVDD10.1007/s11042-013-1412-1 ↗