journal article·2022-08-05Open access

Carbon Nanoparticles and Their Biomedical Applications

Drahomira Holmannova, Pavel Borsky, Tereza Svadlakova, Lenka Borska, Zdenek Fiala

Applied Sciences· Volume 12· Issue 15

Abstract

This review summarizes the current knowledge on current and future applications of carbon nanoparticles in medicine. The carbon nanoparticle family has a large number of representatives with unique physicochemical properties that make them good candidates for use in clinical medicine. The best-known (and most researched) carbon nanoparticles include graphene, graphene oxide, and carbon nanotubes. The main direction of use involves medical diagnostics, which includes bioimaging and the detection of chemicals or metabolites present in the body. Since the question of nanoparticle toxicity has not been fully answered, the use of nanoparticles in the fields of therapeutics (drug delivery), regenerative medicine (cell scaffolding, tissue engineering), and vaccine production is still under research and many in vivo studies are ongoing. These preclinical studies suggest that carbon nanoparticles have great potential for diagnosis and treatment; the results show that the nanoparticles used do not have significant toxic effects; however, great caution is needed before nanoparticles are introduced into routine clinical practice.
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Research context

OpenAlex topics: Graphene and Nanomaterials Applications · Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Preventive Medicine, Faculty of Medicine, Charles University, 500 03 Hradec Králové, Czech Republic

Department of Clinical Immunology and Allergology, University Hospital Hradec Králové and Faculty of Medicine in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic

Funding

ERDF-Project “NANOBIO” · Charles University project SVV · Cooperation Program, research area HEAS

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