Polarization Sensitive Optical Coherence Tomography: A Review of Technology and Applications
Source abstract
Abstract
Polarization sensitive optical coherence tomography (PS-OCT) is an imaging technique based on light scattering. PS-OCT performs rapid two- and three-dimensional imaging of transparent and translucent samples with micrometer scale resolution. PS-OCT provides image contrast based on the polarization state of backscattered light and has been applied in many biomedical fields as well as in non-medical fields. Thereby, the polarimetric approach enabled imaging with enhanced contrast compared to standard OCT and the quantitative assessment of sample polarization properties. In this article, the basic methodological principles, the state of the art of PS-OCT technologies, and important applications of the technique are reviewed in a concise yet comprehensive way.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Optical Coherence Tomography Applications · Photoacoustic and Ultrasonic Imaging · Advanced Fluorescence Microscopy Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Waehringer Guertel 18-20, 4L, 1090 Vienna, Austria
Funding
Austrian Science Fund (FWF) · European Research Council
References (100+)
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1. Optical coherence tomography10.1126/science.1957169 ↗
2. Drexler, W., and Fujimoto, J.G. (2008). Optical Coherence Tomography Technology and Applications, Springer.10.1007/978-3-540-77550-8 ↗
3. Optical coherence tomography—Development, principles, applications10.1016/j.zemedi.2009.11.002 ↗
4. Eye-length measurement by interferometry with partially coherent light10.1364/OL.13.000186 ↗
5. Measurement of intraocular distances by backscattering spectral interferometry10.1016/0030-4018(95)00119-S ↗
6. Optical coherence tomography today: Speed, contrast, and multimodality10.1117/1.JBO.19.7.071412 ↗
7. Polarized light interaction with tissues10.1117/1.JBO.21.7.071114 ↗
8. Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography10.1364/OL.22.000934 ↗
9. Review of polarization sensitive optical coherence tomography and Stokes vector determination10.1117/1.1483879 ↗
10. Polarization sensitive optical coherence tomography—A review10.1364/BOE.8.001838 ↗
11. A new calculus for the treatment of optical systemsi. Description and discussion of the calculus10.1364/JOSA.31.000488 ↗
12. Stokes vectors, Mueller matrices, and polarized scattered light10.1119/1.14202 ↗
13. Polarization-sensitive low-coherence reflectometer for birefringence characterization and ranging10.1364/JOSAB.9.000903 ↗
14. Measurement and imaging of birefringence and optic axis orientation by phase resolved polarization sensitive optical coherence tomography10.1364/OE.9.000780 ↗
15. Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components10.1364/OL.29.002512 ↗
16. Generalized Jones matrix optical coherence tomography: Performance and local birefringence imaging10.1364/OE.18.000854 ↗
17. Determination of local polarization properties of biological samples in the presence of diattenuation by use of Mueller optical coherence tomography10.1364/OL.29.002402 ↗
18. Fiber-based polarization-sensitive OCT of the human retina with correction of system polarization distortions10.1364/BOE.5.002736 ↗
19. Detection of multiple scattering in optical coherence tomography using the spatial distribution of Stokes vectors10.1364/OE.15.018033 ↗
20. Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography10.1364/OE.16.016410 ↗
21. Degree of polarization uniformity with high noise immunity using polarization-sensitive optical coherence tomography10.1364/OL.39.006783 ↗
22. Spectral degree of polarization uniformity for polarization-sensitive OCT10.1080/09500340.2014.945501 ↗
23. Degree of polarization (uniformity) and depolarization index: Unambiguous depolarization contrast for optical coherence tomography10.1364/OL.40.003954 ↗
24. Enhanced depolarization contrast in polarization-sensitive optical coherence tomography10.1364/OL.41.002350 ↗
25. Polarization sensitive optical coherence tomography of melanin provides intrinsic contrast based on depolarization10.1364/BOE.3.001670 ↗
26. Melanin pigmentation in rat eyes: In vivo imaging by polarization-sensitive optical coherence tomography and comparison to histology10.1167/iovs.15-17742 ↗
27. Numerical compensation of system polarization mode dispersion in polarization-sensitive optical coherence tomography10.1364/OE.21.001163 ↗
28. Artifacts in polarization-sensitive optical coherence tomography caused by polarization mode dispersion10.1364/OL.38.000923 ↗
29. Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging10.1364/OE.21.016353 ↗
30. Advanced multi-contrast Jones matrix optical coherence tomography for Doppler and polarization sensitive imaging10.1364/OE.21.019412 ↗
31. In vivo human retinal imaging by Fourier domain optical coherence tomography10.1117/1.1482379 ↗
32. Differential diagnosis of human bladder mucosa pathologies in vivo with cross-polarization optical coherence tomography10.1364/BOE.6.001464 ↗
33. Quantitative evaluation of atherosclerotic plaques using cross-polarization optical coherence tomography, nonlinear, and atomic force microscopy10.1117/1.JBO.21.12.126010 ↗
34. Characterizing of tissue microstructure with single-detector polarization-sensitive optical coherence tomography10.1364/AO.45.004464 ↗
35. Two-dimensional depth-resolved Mueller matrix of biological tissue measured with double-beam polarization-sensitive optical coherence tomography10.1364/OL.27.000101 ↗
36. Depth-resolved two-dimensional Stokes vectors of backscattered light and Mueller matrices of biological tissue measured with optical coherence tomography10.1364/AO.39.006318 ↗
37. Optical-fiber-based Mueller optical coherence tomography10.1364/OL.28.001206 ↗
38. Practical decomposition for physically admissible differential Mueller matrices10.1364/OL.39.001779 ↗
39. Birefringence characterization of biological tissue by use of optical coherence tomography10.1364/OL.23.000228 ↗
40. Transversal phase resolved polarization sensitive optical coherence tomography10.1088/0031-9155/49/7/013 ↗
41. High speed spectral domain polarization sensitive optical coherence tomography of the human retina10.1364/OPEX.13.010217 ↗
42. Single-camera polarization-sensitive spectral-domain OCT by spatial frequency encoding10.1364/OL.35.000241 ↗
43. Mapping local optical axis in birefringent samples using polarization-sensitive optical coherence tomography10.1117/1.JBO.17.11.110501 ↗
44. Mapping local retardance in birefringent samples using polarization sensitive optical coherence tomography10.1364/OL.37.001415 ↗
45. Polarization-sensitive optical coherence tomography based on polarization-maintaining fibers and frequency multiplexing10.1364/OE.16.013032 ↗
46. Polarization maintaining fiber based ultra-high resolution spectral domain polarization sensitive optical coherence tomography10.1364/OE.17.022704 ↗
47. Swept-source polarization-sensitive optical coherence tomography based on polarization-maintaining fiber10.1364/OE.18.003392 ↗
48. Polarization-maintaining fiber based polarization-sensitive optical coherence tomography in spectral domain10.1364/OL.35.000154 ↗
49. Large-field high-speed polarization sensitive spectral domain OCT and its applications in ophthalmology10.1364/BOE.3.002720 ↗
50. High-speed polarization sensitive optical coherence tomography scan engine based on Fourier domain mode locked laser10.1364/BOE.3.002987 ↗
51. Polarization sensitive optical coherence microscopy for brain imaging10.1364/OL.41.002213 ↗
52. All fiber optics circular-state swept source polarization-sensitive optical coherence tomography10.1117/1.JBO.19.2.021110 ↗
53. Design considerations for polarization-sensitive optical coherence tomography with a single input polarization state10.1364/BOE.3.002273 ↗
54. Single input state polarization sensitive swept source optical coherence tomography based on an all single mode fiber interferometer10.1364/BOE.5.002798 ↗
55. Single input state, single-mode fiber-based polarization-sensitive optical frequency domain imaging by eigenpolarization referencing10.1364/OL.40.002025 ↗
56. Form-biattenuance in fibrous tissues measured with polarization-sensitive optical coherence tomography (PS-OCT)10.1364/OPEX.13.004611 ↗
57. Corneal birefringence compensation for polarization sensitive optical coherence tomography of the human retina10.1117/1.2771560 ↗
58. Determination of the depth-resolved Stokes parameters of light backscattered from turbid media by use of polarization-sensitive optical coherence tomography10.1364/OL.24.000300 ↗
59. Jones-matrix imaging of biological tissues with quadruple-channel optical coherence tomography10.1117/1.1483878 ↗
60. Polarization-sensitive complex Fourier domain optical coherence tomography for Jones matrix imaging of biological samples10.1063/1.1804233 ↗
61. Jones matrix imaging of biological samples using parallel-detecting polarization-sensitive Fourier domain optical coherence tomography10.1007/s10043-004-0146-8 ↗
62. Differential geometry of normalized Stokes vector trajectories in anisotropic media10.1364/JOSAA.23.000679 ↗
63. Polarization contrast imaging of biological tissues by polarization-sensitive Fourier-domain optical coherence tomography10.1364/AO.45.001142 ↗
64. High-speed fiber-based polarization-sensitive optical coherence tomography of in vivo human skin10.1364/OL.25.001355 ↗
65. Fiber-based polarization-sensitive Fourier domain optical coherence tomography using B-scan-oriented polarization modulation method10.1364/OE.14.006502 ↗
66. In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography10.1117/1.1413208 ↗
67. Real-time multi-functional optical coherence tomography10.1364/OE.11.000782 ↗
68. Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 µm10.1364/OPEX.13.003931 ↗
69. Optical tractography of the mouse heart using polarization-sensitive optical coherence tomography10.1364/BOE.4.002540 ↗
70. High resolution imaging of the fibrous microstructure in bovine common carotid artery using optical polarization tractography10.1002/jbio.201500229 ↗
71. High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing10.1364/OE.16.001096 ↗
72. Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra a-line polarization modulation10.1364/OL.33.001330 ↗
73. Swept source/Fourier domain polarization sensitive optical coherence tomography with a passive polarization delay unit10.1364/OE.20.010229 ↗
74. Passive component based multifunctional Jones matrix swept source optical coherence tomography for Doppler and polarization imaging10.1364/OL.37.001958 ↗
75. Method to calibrate phase fluctuation in polarization-sensitive swept-source optical coherence tomography10.1117/1.3597721 ↗
76. Imaging myocardial fiber orientation using polarization sensitive optical coherence tomography10.1364/BOE.4.000460 ↗
77. Longitudinal, 3D imaging of collagen remodeling in murine hypertrophic scars in vivo using polarization-sensitive optical frequency domain imaging10.1038/JID.2015.399 ↗
78. Three-dimensional multi-contrast imaging of in vivo human skin by Jones matrix optical coherence tomography10.1364/BOE.8.001290 ↗
79. In vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer by polarization-sensitive optical coherence tomography10.1364/OL.27.001610 ↗
80. Simultaneous intensity, birefringence, and flow measurements with high-speed fiber-based optical coherence tomography10.1364/OL.27.001534 ↗
81. Performance of fourier domain vs. Time domain optical coherence tomography10.1364/OE.11.000889 ↗
82. Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography10.1364/OL.28.002067 ↗
83. Sensitivity advantage of swept source and Fourier domain optical coherence tomography10.1364/OE.11.002183 ↗
84. Single camera based spectral domain polarization sensitive optical coherence tomography10.1364/OE.15.001054 ↗
85. Polarization-sensitive spectral-domain optical coherence tomography using a single line scan camera10.1364/OE.15.002421 ↗
86. Single-camera sequential-scan-based polarization-sensitive SDOCT for retinal imaging10.1364/OL.34.000205 ↗
87. Single camera spectral domain polarization-sensitive optical coherence tomography using offset B-scan modulation10.1364/OE.18.007281 ↗
88. High-speed spectral domain polarization-sensitive optical coherence tomography using a single camera and an optical switch at 1.3 µm10.1117/1.3277668 ↗
89. Polarization-sensitive spectral-domain optical coherence tomography using a multi-line single camera spectrometer10.1364/OE.18.023805 ↗
90. Wavelength-tuning interferometry of intraocular distances10.1364/AO.36.006548 ↗
91. Optical frequency-domain reflectometry using rapid wavelength tuning of a Cr4+: Forsterite laser10.1364/OL.22.001704 ↗
92. High-speed OCT light sources and systems10.1364/BOE.8.000828 ↗
93. Full range polarization-sensitive Fourier domain optical coherence tomography10.1364/OPEX.12.006033 ↗
94. Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation10.1364/OE.16.005892 ↗
95. Investigation of post-glaucoma-surgery structures by three-dimensional and polarization sensitive anterior eye segment optical coherence tomography10.1364/OE.17.003980 ↗
96. Full-range polarization-sensitive swept-source optical coherence tomography by simultaneous transversal and spectral modulation10.1364/OE.18.013964 ↗
97. Polarization-sensitive optical frequency domain imaging based on unpolarized light10.1364/OE.19.000552 ↗
98. Automated measurement of choroidal thickness in the human eye by polarization sensitive optical coherence tomography10.1364/OE.20.007564 ↗
99. Retinal polarization-sensitive optical coherence tomography at 1060 nm with 350 kHz a-scan rate using an Fourier domain mode locked laser10.1117/1.JBO.18.2.026008 ↗
100. Optically buffered Jones-matrix-based multifunctional optical coherence tomography with polarization mode dispersion correction10.1364/BOE.6.000225 ↗