journal article·2021-01-26Open access

Review on Silver Nanoparticles as a Novel Class of Antibacterial Solutions

Corina Michaela Crisan, Teodora Mocan, Meda Manolea, Lavinia Iulia Lasca, Flaviu-Alexandru Tăbăran, Lucian Mocan

Applied Sciences· Volume 11· Issue 3

Abstract

Nanomaterials represent a promising novel class of materials to be used as antibacterial solutions. Inhomogeneity of synthesis and characterization methods, as well as resulting variate physical and chemical properties make selection of proper nanostructure difficult when designing antimicrobial experiments. Present study focuses on the already existing evidence regarding silver nanoparticles and their antibacterial applications, with focus on various modulatory factors of reported antimicrobial efficiency. Present paper focuses on synthesis and characterization methods, factors modulating antibacterial efficiency, laboratory quantification procedures, as well as up–to-date knowledge on mechanisms of antibacterial action for silver nanoparticles. Moreover, challenges and future prospects for antimicrobial applications of silver nanoparticles are reviewed and discussed.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Nanoparticles: synthesis and applications · Gold and Silver Nanoparticles Synthesis and Applications · Advanced Nanomaterials in Catalysis

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

3-rd Surgery Clinic, University of Medicine and Pharmacy, 400162 Cluj-Napoca, Romania

Physiology Discipline, University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania

Nanomedicine Department, Regional Institute of Gastroenterology and Hepatology, 400162 Cluj-Napoca, Romania

Emergency Hospital, 410169 Oradea, Romania

Pathology Department, University of Agriculture Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania

Funding

Universitatea de Medicină şi Farmacie Iuliu Haţieganu Cluj-Napoca · Consiliul National al Cercetarii Stiintifice

References (75)

Show source-provided references
1. Green synthesis of silver nanoparticles: Characterization and determination of antibacterial potency10.1007/s13204-015-0426-6 ↗
2. Vancomycin Capped with Silver Nanoparticles as an Antibacterial Agent against Multi-Drug Resistance Bacteria10.15171/apb.2017.058 ↗
3. Antibacterial Effect of Silver Nanoparticles on Klebsiella spp.10.47285/hr.v1i2.54 ↗
4. Self-assembled N-doped Q-dot carbon nanostructures as a SERS-active biosensor with selective therapeutic functionality10.1016/j.snb.2020.128703 ↗
5. Functionalized carbon-based nanomaterials and quantum dots with antibacterial activity: A review
6. MoS 2@ polydopamine-Ag nanosheets with enhanced antibacterial activity for effective treatment of Staphylococcus aureus biofilms and wound infection10.1039/C8NR04111C ↗
7. Rauwel, P., Küünal, S., Ferdov, S., and Rauwel, E. (2015). A review on the green synthesis of silver nanoparticles and their morphologies studied via TEM. Adv. Mater. Sci. Eng., 1–9.10.1155/2015/682749 ↗
8. Green synthesis and characterization of bioinspired silver, gold and platinum nanoparticles and evaluation of their synergistic antibacterial activity after combining with different classes of antibiotics10.1016/j.msec.2018.11.050 ↗
9. Antibacterial activity of pH-dependent biosynthesized silver nanoparticles against clinical pathogen10.1155/2014/725165 ↗
10. Raza, M.A., Kanwal, Z., Rauf, A., Sabri, A.N., Riaz, S., and Naseem, S. (2016). Size-and shape-dependent antibacterial studies of silver nanoparticles synthesized by wet chemical routes. Nanomaterials, 6.10.3390/nano6040074 ↗
11. Feng, A., Cao, J., Wei, J., Chang, F., Yang, Y., and Xiao, Z. (2018). Facile Synthesis of Silver Nanoparticles with High Antibacterial Activity. Materials, 11.10.3390/ma11122498 ↗
12. Antibacterial activity of silver nanoparticles target sara through srna-teg49, a key mediator of hfq, in staphylococcus aureus
13. Biogenic pentagonal silver nanoparticles for safer and more effective antibacterial therapeutics10.2147/IJN.S168224 ↗
14. Synthesis of silver nanoparticles: Chemical, physical and biological methods
15. Nacl: For the safer in vivo use of antibacterial silver based nanoparticles10.2147/IJN.S153168 ↗
16. Cellulose Whiskers Influence the Morphology and Antibacterial Properties of Silver Nanoparticles Composites10.1166/jnn.2018.15285 ↗
17. Non-cytotoxic effect of green synthesized silver nanoparticles and its antibacterial activity10.1016/j.jphotobiol.2017.10.010 ↗
18. Preparation of poly (lactide)/lignin/silver nanoparticles composite films with UV light barrier and antibacterial properties10.1016/j.ijbiomac.2017.10.038 ↗
19. Surface ligand controls silver ion release of nanosilver and its antibacterial activity against Escherichia coli10.2147/IJN.S132327 ↗
20. Antibacterial efficacy of silver nanoparticles against multi-drug resistant clinical isolates from post-surgical wound infections10.1016/j.micpath.2017.04.013 ↗
21. Evaluation of cytotoxicity, immune compatibility and antibacterial activity of biogenic silver nanoparticles10.1007/s00430-016-0477-7 ↗
22. Mechanistic study of the synergistic antibacterial activity of combined silver nanoparticles and common antibiotics10.1021/acs.est.6b00998 ↗
23. Panáček, A., Smékalová, M., Kilianová, M., Prucek, R., Bogdanová, K., Večeřová, R., Kolář, M., Havrdová, M., Płaza, G., and Chojniak, J. (2016). Strong and nonspecific synergistic antibacterial efficiency of antibiotics combined with silver nanoparticles at very low concentrations showing no cytotoxic effect. Molecules, 21.10.3390/molecules21010026 ↗
24. Hortigüela, M.J., Yuste, L., Rojo, F., and Aranaz, I. (2016). Green synthesis of hierarchically structured silver-polymer nanocomposites with antibacterial activity. Nanomaterials, 6.10.3390/nano6080137 ↗
25. Charge stabilized silver nanoparticles applied as antibacterial agents10.1166/jnn.2015.9727 ↗
26. Sumac silver novel biodegradable nano composite for bio-medical application: Antibacterial activity10.3390/molecules200712946 ↗
27. Impact of protecting ligands on surface structure and antibacterial activity of silver nanoparticles10.1021/acs.langmuir.5b00049 ↗
28. Enhanced stability and antibacterial efficacy of a traditional Chinese medicine-mediated silver nanoparticle delivery system
29. Synthesis of silver nanoparticles and antibacterial property of silk fabrics treated by silver nanoparticles10.1186/1556-276X-9-216 ↗
30. Synthesis, characterization, and evaluation of antibacterial effect of Ag nanoparticles against Escherichia coli O157:H7 and methicillin-resistant Staphylococcus aureus (MRSA)
31. Antibacterial activity and synergistic effect of biosynthesized AgNPs with antibiotics against multidrug-resistant biofilm-forming coagulase-negative staphylococci isolated from clinical samples10.1007/s12010-014-0852-z ↗
32. Antibacterial activity and mechanism of Ag–ZnO nanocomposite on S. aureus and GFP-expressing antibiotic resistant E. coli10.1016/j.colsurfb.2013.12.005 ↗
33. Characterization techniques for nanoparticles: Comparison and complementarity upon studying nanoparticle properties10.1039/C8NR02278J ↗
34. Current applications of X-ray powder diffraction—A review
35. Femtosecond X-ray protein nanocrystallography10.1038/nature09750 ↗
36. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution10.1021/mp800032f ↗
37. Optical properties and ultrafast dynamics of metallic nanocrystals10.1146/annurev.physchem.54.011002.103759 ↗
38. Preparation of polychrome silver nanoparticles in different solvents10.1039/b205214h ↗
39. Following enzyme activity with infrared spectroscopy10.3390/s100402626 ↗
40. Characterization of dendrimers by X-ray photoelectron spectroscopy10.1366/0003702991945524 ↗
41. Particle size distribution measurements of manganese-doped ZnS nanoparticles10.1021/ac900043y ↗
42. Augmented antibacterial activity of ampicillin with silver nanoparticles against methicillin-resistant Staphylococcus aureus (MRSA)10.1038/s41429-018-0111-6 ↗
43. Corn cob silica as an antibacterial support for silver nanoparticles: Efficacy on Escherichia coli and Listeria monocytogenes10.1007/s10661-018-6954-2 ↗
44. Synergetic effect of vancomycin loaded silver nanoparticles for enhanced antibacterial activity10.1016/j.colsurfb.2018.12.043 ↗
45. Antibacterial Activity of Silver Nanoparticles: Structural Effects10.1002/adhm.201701503 ↗
46. Plasma membrane is the target of rapid antibacterial action of silver nanoparticles in Escherichia coli and Pseudomonas aeruginosa10.2147/IJN.S177163 ↗
47. Vasil’kov, A., Dovnar, R., Smotryn, S., Iaskevich, N., and Naumkin, A. (2018). Plasmon Resonance of Silver Nanoparticles as a Method of Increasing Their Antibacterial Action. Antibiotics, 7.10.3390/antibiotics7030080 ↗
48. Antibacterial effects and resistance induction of silver and gold nanoparticles against Staphylococcus aureus-induced mastitis and the potential toxicity in rats10.1002/mbo3.698 ↗
49. Surface coating and particle size are main factors explaining the transcriptome-wide responses of the earthworm Lumbricus rubellus to silver nanoparticles10.1039/C9EN01144G ↗
50. Silver nanoparticles with different size and shape: Equal cytotoxicity, but different antibacterial effects10.1039/C5RA27836H ↗
51. The effects of bacteria-nanoparticles interface on the antibacterial activity of green synthesized silver nanoparticles10.1016/j.micpath.2016.11.030 ↗
52. Silver nanoparticles as potential antibacterial agents10.3390/molecules20058856 ↗
53. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances10.1038/nprot.2007.521 ↗
54. Antibacterial activity of ZnO nanoparticle on gram-positive and gram-negative bacteria
55. Biogenic nanoparticles bearing antibacterial activity and their synergistic effect with broad spectrum antibiotics: Emerging strategy to combat drug resistant pathogens10.1016/j.jsps.2015.06.011 ↗
56. Eco-friendly approach to the synthesis of silver nanoparticles and their antibacterial activity against Staphylococcus spp. and Escherichia coli10.1080/10934529.2018.1474568 ↗
57. Green synthesis: Proposed mechanism and factors influencing the synthesis of platinum nanoparticles10.1515/gps-2020-0041 ↗
58. Simple green production of silver nanoparticles facilitated by bacterial genomic DNA and their antibacterial activity10.1080/21691401.2017.1332638 ↗
59. Functional nanonetwork-structured polymers and carbons with silver nanoparticle yolks for antibacterial application10.1039/C7CC04621A ↗
60. Silver nanoparticle/bacterial cellulose gel membranes for antibacterial wound dressing: Investigation in vitro and in vivo10.1088/1748-6041/9/3/035005 ↗
61. An improved green synthesis method and Escherichia coli antibacterial activity of silver nanoparticles10.1016/j.jphotobiol.2018.04.002 ↗
62. Biosynthesis of silver nanoparticles using chlorella vulgaris and evaluation of the antibacterial efficacy against staphylococcus aureus
63. Characterization and in vitro antibacterial activity of saponin-conjugated silver nanoparticles against bacteria that cause burn wound infection10.1007/s11274-017-2309-3 ↗
64. A novel mechanism for the antibacterial effect of silver nanoparticles on Escherichia coli10.1007/s10534-014-9782-z ↗
65. Role of efflux pumps in the antibiotic resistance of bacteria embedded in a biofilm10.4161/viru.23724 ↗
66. Both silver ions and silver nanoparticles facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes10.1016/j.watres.2019.115229 ↗
67. Salleh, A., Naomi, R., Utami, N.D., Mohammad, A.W., Mahmoudi, E., Mustafa, N., and Fauzi, M.B. (2020). The potential of silver nanoparticles for antiviral and antibacterial applications: A mechanism of action. Nanomaterials, 10.10.3390/nano10081566 ↗
68. Evaluation of the mechanical, physical and antimicrobial properties of chitosan thin films doped with greenly synthesized silver nanoparticles10.1016/j.mtcomm.2020.101372 ↗
69. Label-free SERS quantum semiconductor probe for molecular-level and in vitro cellular detection: A Noble-metal-free methodology10.1021/acsami.8b10590 ↗
70. Oroactive dental biomaterials and their use in endodontic therapy10.1002/jbm.b.34379 ↗
71. Antimicrobial ultrathin film based on well-defined silver nanoparticles and polylactide10.1088/2043-6254/ab92f9 ↗
72. Preparation of silver nanoparticles and riboflavin embedded electrospun polymer nanofibrous scaffolds for in vivo wound dressing application10.1016/j.procbio.2019.09.033 ↗
73. In vitro and in vivo evaluation of structurally-controlled silk fibroin coatings for orthopedic infection and in-situ osteogenesis10.1016/j.actbio.2020.08.040 ↗
74. New biodegradable nanoparticles-in-nanofibers based membranes for guided periodontal tissue and bone regeneration with enhanced antibacterial activity10.1016/j.jare.2020.06.014 ↗
75. Fiorati, A., Bellingeri, A., Punta, C., Corsi, I., and Venditti, I. (2020). Silver Nanoparticles for Water Pollution Monitoring and Treatments: Ecosafety Challenge and Cellulose-Based Hybrids Solution. Polymers, 12.10.3390/polym12081635 ↗