journal article·2019-05-29Open access

Morphology and Properties of Electrospun PCL and Its Composites for Medical Applications: A Mini Review

Mokgaotsa Jonas Mochane, Teboho Simon Motsoeneng, Emmanuel Rotimi Sadiku, Teboho Clement Mokhena, Jeremia Shale Sefadi

Applied Sciences· Volume 9· Issue 11

Abstract

Polycaprolactone (PCL) is one of the most used synthetic polymers for medical applications due to its biocompatibility and slow biodegradation character. Combining the inherent properties of the PCL matrix with the characteristic of nanofibrous particles, result into promising materials that can be suitable for different applications, including the biomedical applications. The advantages of nanofibrous structures include large surface area, a small diameter of pores and a high porosity, which make them of great interest in different applications. Electrospinning, as technique, has been heavily used for the preparation of nano- and micro-sized fibers. This review discusses the different methods for the electrospinning of PCL and its composites for advanced applications. Furthermore, the steady state conditions as well as the effect of the electrospinning parameters on the resultant morphology of the electrospun fiber are also reported.
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Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Advanced Sensor and Energy Harvesting Materials · biodegradable polymer synthesis and properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Life Sciences, Central University of Technology, Free State, Private Bag X20539, Bloemfontein 9301, South Africa

Department of Chemistry, University of South Africa, Gauteng, Florida 1709, South Africa

Institute of NanoEngineering Research (INER), Department of Chemical, Metallurgical and Materials Engineering, Tshwane University of Technology, RSA, Pretoria 0001, South Africa

CSIR Materials Science and Manufacturing, Polymers and Composites, Port Elizabeth 6000, South Africa

Department of Chemistry, Nelson Mandela University, Port Elizabeth 6031, South Africa

School of Natural and Applied Sciences, Sol Plaatje University, Kimberley 8301, South Africa

Funding

National Research Funding (NRF) Thuthuka, South Africa

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