Transdifferentiation and adult stem cells: Myth or reality?
Source abstract
Abstract
The paper by Kruse et al. published in this issue of Applied Physics A claims that cells isolated from pancreas of adult rats or humans can generate cells of multiple lineages. To convincingly show “transdifferentiation” of adult stem cells across lineage boundaries requires stringent experimental criteria such as clonal analyses. The data provided by Kruse et al. fall short of such standards and the conclusion that multipotential cells were isolated is unconvinving.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Pluripotent Stem Cells Research · Mesenchymal stem cell research · Biomedical Ethics and Regulation
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References (9)
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