Green synthesis of Gold nanoparticles via Annona muricata fruit extract: antioxidant, and antidiabetic potential

1. Z.M. Abbas, W.A. Shatti, A.M. Mohammad, Z.T. Khodair, Magnetic iron oxide: preparation and characterization for antibacterial activity applications. J. Sol-Gel Sci. Technol. 109(2), 534–542 (2024)10.1007/s10971-023-06300-w ↗

2. M.S. Ardestani, A. Bitarafan-Rajabi, P. Mohammadzadeh, S. Mortazavi-Derazkola, O. Sabzevari, A.D. Azar, S. Kazemi, S.R. Hosseini, S.M. Ghoreishi, Synthesis and characterization of novel 99mTc-DGC nano-complexes for improvement of heart diagnostic. Bioorg. Chem. 96, 103572 (2020)10.1016/j.bioorg.2020.103572 ↗

3. Z.T. Khodair, N.M. Ibrahim, T.J. Kadhim, A.M. Mohammad, Synthesis and characterization of nickel oxide (NiO) nanoparticles using an environmentally friendly method, and their biomedical applications. Chem. Phys. Lett. 797, 139564 (2022)10.1016/j.cplett.2022.139564 ↗

4. H.S. Ahmed, S.R. Saeed, A.M. Mohammad, Influence of calcination temperature on magnetic properties and antibacterial activities of Co–Ni-Cd-Fe2O4 nanocomposites. J. Supercond. Nov. Magn. 38(3), 1–14 (2025)10.1007/s10948-025-06988-7 ↗

5. M.B. Jumaa, T.H. Mubarak, A.M. Mohammad, Exploring Cu-substituted Zn nanoferrites: synthesis, structural, magnetic, morphological, and antibacterial properties. J. Sol-Gel Sci. Technol. 114(3), 841–856 (2025)10.1007/s10971-025-06742-4 ↗

6. A.E. Adebayo, A.M. Oke, A. Lateef, A.A. Oyatokun, O.D. Abisoye, I.P. Adiji, D.O. Fagbenro, T.V. Amusan, J. Badmus, T. Asafa, Biosynthesis of silver, gold and silver–gold alloy nanoparticles using Persea americana fruit peel aqueous extract for their biomedical properties. Nanotechnol. Environ. Eng. 4, 1–15 (2019)10.1007/s41204-019-0060-8 ↗

7. N.J. Alaallah, E. Abd Alkareem, A. Ghaidan, N.A. Imran, Eco-friendly approach for silver nanoparticles synthesis from lemon extract and their anti-oxidant, anti-bacterial, and anti-cancer activities. J. Turk. Chem. Soc. Sect. A Chem. 10(1), 205–216 (2023)10.18596/jotcsa.1159851 ↗

8. V. Sekar, C. Balakrishnan, P. Kathirvel, S. Swamiappan, M.A. Alshehri, S. Sayed, C. Panneerselvam, Ultra-sonication-enhanced green synthesis of silver nanoparticles using Barleria buxifolia leaf extract and their possible application. Artif. Cells Nanomed. Biotechnol. 50(1), 177–187 (2022)10.1080/21691401.2022.2084100 ↗

9. G.M. Sulaiman, W.H. Mohammed, T.R. Marzoog, A.A.A. Al-Amiery, A.A.H. Kadhum, A.B. Mohamad, Green synthesis, antimicrobial and cytotoxic effects of silver nanoparticles using Eucalyptus chapmaniana leaves extract. Asian Pac. J. Trop. Biomed. 3(1), 58–63 (2013)10.1016/S2221-1691(13)60024-6 ↗

10. B. Sun, N. Hu, L. Han, Y. Pi, Y. Gao, K. Chen, Anticancer activity of green synthesised gold nanoparticles from Marsdenia tenacissima inhibits A549 cell proliferation through the apoptotic pathway. Artif. Cells Nanomed. Biotechnol. 47(1), 4012–4019 (2019)10.1080/21691401.2019.1575844 ↗

11. U.K. Parida, B.K. Bindhani, P. Nayak, Green synthesis and characterization of gold nanoparticles using onion (Allium cepa) extract. World J Nano Sci Eng 1(04), 93 (2011)10.4236/wjnse.2011.14015 ↗

12. R.K. Das, N. Gogoi, U. Bora, Green synthesis of gold nanoparticles using Nyctanthes arbortristis flower extract. Bioprocess Biosyst. Eng. 34, 615–619 (2011)10.1007/s00449-010-0510-y ↗

13. K.P. Kumar, W. Paul, C.P. Sharma, Green synthesis of gold nanoparticles with Zingiber officinale extract: characterization and blood compatibility. Process Biochem. 46(10), 2007–2013 (2011)10.1016/j.procbio.2011.07.011 ↗

14. B. Sadeghi, M. Mohammadzadeh, B. Babakhani, Green synthesis of gold nanoparticles using Stevia rebaudiana leaf extracts: characterization and their stability. J. Photochem. Photobiol. B Biol. 148, 101–106 (2015)10.1016/j.jphotobiol.2015.03.025 ↗

15. S.J. Mary, V. Veeravarmal, P. Thankappan, P. Arumugam, P.I. Augustine, R. Franklin, Anti-cancer effects of green synthesized gold nanoparticles using leaf extract of Annona muricata L against squamous cell carcinoma cell line 15 through apoptotic pathway. Dent. Res. J. 21(1), 14 (2024)

16. I.L. Santos, AMd.C. Rodrigues, E.R. Amante, L.HMd. Silva, Soursop (Annona muricata) properties and perspectives for integral valorization. Foods 12(7), 1448 (2023)10.3390/foods12071448 ↗

17. N. Badrie, A.G. Schauss, Soursop (Annona muricata L.): composition, nutritional value, medicinal uses, and toxicology, in Bioactive foods in promoting health. (2010), pp.621–64310.1016/B978-0-12-374628-3.00039-6 ↗

18. S.M. Abdul Wahab, I. Jantan, M.A. Haque, L. Arshad, Exploring the leaves of Annona muricata L. as a source of potential anti-inflammatory and anticancer agents. Front. Pharmacol. 9, 661 (2018)10.3389/fphar.2018.00661 ↗

19. N.S. Al-Radadi, Synthesis, characterization, antimalarial, antimicrobial, and antioxidant activities of GNPs with Annona muricata leaf extract. Arab. J. Chem. 18(1), 106081 (2025)

20. A.I. Usman, A.A. Aziz, O.A. Noqta, Application of green synthesis of gold nanoparticles: a review. Jurnal Teknologi (Sciences & Engineering) 81(1), 171–182 (2019)

21. M. Hosny, M. Fawzy, A.M. Abdelfatah, E.E. Fawzy, A.S. Eltaweil, Comparative study on the potentialities of two halophytic species in the green synthesis of gold nanoparticles and their anticancer, antioxidant and catalytic efficiencies. Adv. Powder Technol. 32(9), 3220–3233 (2021)10.1016/j.apt.2021.07.008 ↗

22. V. Soshnikova, Y.J. Kim, P. Singh, Y. Huo, J. Markus, S. Ahn, V. Castro-Aceituno, J. Kang, M. Chokkalingam, R. Mathiyalagan, Cardamom fruits as a green resource for facile synthesis of gold and silver nanoparticles and their biological applications. Artif. Cells Nanomed. Biotechnol. 46(1), 108–117 (2018)10.1080/21691401.2017.1296849 ↗

23. D. Villaño, M. Fernández-Pachón, M.L. Moyá, A. Troncoso, M. García-Parrilla, Radical scavenging ability of polyphenolic compounds towards DPPH free radical. Talanta 71(1), 230–235 (2007)10.1016/j.talanta.2006.03.050 ↗

24. P. Prieto, M. Pineda, M. Aguilar, Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. Anal. Biochem. 269(2), 337–341 (1999)10.1006/abio.1999.4019 ↗

25. S. Donga, G.R. Bhadu, S. Chanda, Antimicrobial, antioxidant and anticancer activities of gold nanoparticles green synthesized using Mangifera indica seed aqueous extract. Artif. Cells Nanomed. Biotechnol. 48(1), 1315–1325 (2020)10.1080/21691401.2020.1843470 ↗

26. K. Balan, W. Qing, Y. Wang, X. Liu, T. Palvannan, Y. Wang, F. Ma, Y. Zhang, Antidiabetic activity of silver nanoparticles from green synthesis using Lonicera japonica leaf extract. RSC Adv. 6(46), 40162–40168 (2016)10.1039/C5RA24391B ↗

27. M. Telagari, K. Hullatti, In-vitro α-amylase and α-glucosidase inhibitory activity of Adiantum caudatum Linn. and Celosia argentea Linn. extracts and fractions. Indian J. Pharmacol. 47(4), 425 (2015)10.4103/0253-7613.161270 ↗

28. T.P. Patil, A.A. Vibhute, S.L. Patil, T.D. Dongale, A.P. Tiwari, Green synthesis of gold nanoparticles via Capsicum annum fruit extract: characterization, antiangiogenic, antioxidant and anti-inflammatory activities. Appl. Surf. Sci. Adv. 13, 100372 (2023)10.1016/j.apsadv.2023.100372 ↗

29. A. Zuhrotun, D.J. Oktaviani, A.N. Hasanah, Biosynthesis of gold and silver nanoparticles using phytochemical compounds. Molecules 28(7), 3240 (2023)10.3390/molecules28073240 ↗

30. J. Mehdi, V.A. Ansari and A. Singh, A review of gold nanoparticles: synthesis methods and biomedical applications. Biomedical Materials & Devices. 1–17 (2025)10.1007/s44174-025-00421-2 ↗

31. A. Pugazhendhi, D. Prabakar, J.M. Jacob, I. Karuppusamy, R.G. Saratale, Synthesis and characterization of silver nanoparticles using Gelidium amansii and its antimicrobial property against various pathogenic bacteria. Microb. Pathog. 114, 41–45 (2018)10.1016/j.micpath.2017.11.013 ↗

32. E.G. Döll, E.R. Santana, J.P. Winiarski, L.G. Baumgarten, I.C. Vieira, Green synthesis of gold nanoparticles using peach extract incorporated in graphene for the electrochemical determination of antioxidant butylated hydroxyanisole in food matrices. Biosensors 13(12), 1037 (2023)

33. Y. Gavamukulya, E.N. Maina, A.M. Meroka, E.S. Madivoli, H.A. El-Shemy, F. Wamunyokoli, G. Magoma, Green synthesis and characterization of highly stable silver nanoparticles from ethanolic extracts of fruits of Annona muricata. J. Inorg. Organomet. Polym. Mater. 30(4), 1231–1242 (2020)10.1007/s10904-019-01262-5 ↗

34. S. Santhosh, R. Yuvarajan, D. Natarajan, Annona muricata leaf extract-mediated silver nanoparticles synthesis and its larvicidal potential against dengue, malaria and filariasis vector. Parasitol. Res. 114, 3087–3096 (2015)10.1007/s00436-015-4511-2 ↗

35. A.M. Mohammad, S.K. Fatah, M.H. Majeed, S.M. Mohammed, S.M. Mohammed, Enhanced antibacterial activity and structural characterization of ZnO-doped MgO nanocomposites synthesized via sol–gel technique. Bionanoscience. 14(2), 1228–1241 (2024)10.1007/s12668-024-01384-2 ↗

36. M. Hamelian, K. Varmira, H. Veisi, Green synthesis and characterizations of gold nanoparticles using thyme and survey cytotoxic effect, antibacterial and antioxidant potential. J. Photochem. Photobiol. B, Biol. 184, 71–79 (2018)10.1016/j.jphotobiol.2018.05.016 ↗

37. T.-T. Vo, T.T.-N. Nguyen, T.T.-T. Huynh, T.T.-T. Vo, T.T.-N. Nguyen, D.-T. Nguyen, V.-S. Dang, C.-H. Dang, T.-D. Nguyen, Biosynthesis of silver and gold nanoparticles using aqueous extract from Crinum latifolium leaf and their applications forward antibacterial effect and wastewater treatment. J. Nanomater. 2019(1), 8385935 (2019)

38. W.A. Shatti, Z.M. Abbas, A.M. Mohammad, S.M. Mohammed, Structural and electrical properties of Al3+ substituted cobalt ferrite nanoparticles for improved antibacterial activity. J. Supercond. Novel Magn. 38(1), 40 (2025)10.1007/s10948-024-06851-1 ↗

39. U. Chakraborty, G. Bhanjana, N. Kaur, R. Sharma, G. Kaur, A. Kaushik, G.R. Chaudhary, Microwave-assisted assembly of Ag2O-ZnO composite nanocones for electrochemical detection of 4-nitrophenol and assessment of their photocatalytic activity towards degradation of 4-nitrophenol and methylene blue dye. J. Hazard. Mater. 416, 125771 (2021)10.1016/j.jhazmat.2021.125771 ↗

40. F. Wu, J. Zhu, G. Li, J. Wang, V.P. Veeraraghavan, S. Krishna. Mohan, Q. Zhang, Biologically synthesized green gold nanoparticles from Siberian ginseng induce growth-inhibitory effect on melanoma cells (B16). Artif. Cells Nanomed. Biotechnol. 47(1), 3297–3305 (2019)10.1080/21691401.2019.1647224 ↗

41. A. Mohammad, M. Mohammed, L. Hussein, Structural, magnetic and optical properties of Co0.5Ni0.5Fe2O4 nanoparticles synthesized by sol-gel auto combustion method. Dig. J. Nanomater. Biostruct. 15(1), 231–241 (2020)10.15251/DJNB.2020.151.231 ↗

42. U.M. Badeggi, E. Ismail, A.O. Adeloye, S. Botha, J.A. Badmus, J.L. Marnewick, C.N. Cupido, A.A. Hussein, Green synthesis of gold nanoparticles capped with procyanidins from Leucosidea sericea as potential antidiabetic and antioxidant agents. Biomolecules 10(3), 452 (2020)10.3390/biom10030452 ↗

43. N.E.-A. El-Naggar, S.E. El-Malkey, M. Abu-Saied, A.A. Mohammed, Exploration of a novel and efficient source for production of bacterial nanocellulose, bioprocess optimization and characterization. Sci. Rep. 12(1), 18533 (2022)

44. B. Kabak, D. Trak, E. Kendüzler, Y. Arslan, Novel approach for green synthesis of stable gold nanoparticles with dried turmeric root extract: investigations on sensor and catalytic applications. Environ. Sci. Pollut. Res. 31(38), 50614–50629 (2024)10.1007/s11356-024-34588-w ↗

45. N.E.-A. El-Naggar, A.A. El-Sawah, M.F. Elmansy, O.T. Elmessiry, M.E. El-Saidy, M.K. El-Sherbeny, M.T. Sarhan, A.A. Elhefnawy, S.R. Dalal, Process optimization for gold nanoparticles biosynthesis by Streptomyces albogriseolus using artificial neural network, characterization and antitumor activities. Sci. Rep. 14(1), 4581 (2024)

46. N.E.-A. El-Naggar, S.R. Dalal, A.M. Zweil, M. Eltarahony, Artificial intelligence-based optimization for chitosan nanoparticles biosynthesis, characterization and in-vitro assessment of its anti-biofilm potentiality. Sci. Rep. 13(1), 4401 (2023)

47. T.H. Mubarak, M.B. Jumaa, A.M. Mohammad, Structural, magnetic, and antibacterial properties of Ni1− xCuxFe2O4 nanocomposites: influence of Cu substitution. Appl. Phys. A 131(10), 1–19 (2025)10.1007/s00339-025-08893-1 ↗

48. M.N. Owaid, M.A. Rabeea, A.A. Aziz, M.S. Jameel, M.A. Dheyab, Mushroom-assisted synthesis of triangle gold nanoparticles using the aqueous extract of fresh Lentinula edodes (shiitake), Omphalotaceae. Environ. Nanotechnol. Monit. Manag. 12, 100270 (2019)

49. A. Muthuvel, K. Adavallan, K. Balamurugan, N. Krishnakumar, Biosynthesis of gold nanoparticles using Solanum nigrum leaf extract and screening their free radical scavenging and antibacterial properties. Biomed. Prev. Nutr. 4(2), 325–332 (2014)10.1016/j.bionut.2014.03.004 ↗

50. P.P. Dutta, M. Bordoloi, K. Gogoi, S. Roy, B. Narzary, D.R. Bhattacharyya, P.K. Mohapatra, B. Mazumder, Antimalarial silver and gold nanoparticles: green synthesis, characterization and in vitro study. Biomed. Pharmacother. 91, 567–580 (2017)10.1016/j.biopha.2017.04.032 ↗

51. K. Prashanth, R. Onkarappa, Germicidal properties of biosynthesised gold nanoparticles from Streptomyces sp. PRO 15. Biosci. Biotechnol. Res. Commun. 14, 1118–1123 (2021)10.21786/bbrc/14.3.32 ↗

52. K. Sirivibulkovit, S. Nouanthavong, Y. Sameenoi, Based DPPH assay for antioxidant activity analysis. Anal. Sci. 34(7), 795–800 (2018)10.2116/analsci.18P014 ↗

53. K.H. Oh, V. Soshnikova, J. Markus, Y.J. Kim, S.C. Lee, P. Singh, V. Castro-Aceituno, S. Ahn, D.H. Kim, Y.J. Shim, Biosynthesized gold and silver nanoparticles by aqueous fruit extract of Chaenomeles sinensis and screening of their biomedical activities. Artif. Cells Nanomed. Biotechnol. 46(3), 599–606 (2018)10.1080/21691401.2017.1332636 ↗

54. A. Folorunso, S. Akintelu, A.K. Oyebamiji, S. Ajayi, B. Abiola, I. Abdusalam, A. Morakinyo, Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata. J. Nanostruct. Chem. 9, 111–117 (2019)10.1007/s40097-019-0301-1 ↗

55. R. Raybaudi-Massilia, A. Suárez, F. Arvelo, F. Sojo, J. Mosqueda-Melgar, A. Zambrano, M. Calderón-Gabaldón, An analysis in-vitro of the cytotoxic, antioxidant and antimicrobial activity of aqueous and alcoholic extracts of Annona muricata L. seed and pulp. British Journal of Applied Science & Technology 5(4), 333–341 (2015)10.9734/BJAST/2015/13587 ↗

56. F. Ameen, K.S. Al-Maary, A. Almansob, S. AlNadhari, Antioxidant, antibacterial and anticancer efficacy of Alternaria chlamydospora-mediated gold nanoparticles. Appl. Nanosci. 13(3), 2233–2240 (2023)10.1007/s13204-021-02047-4 ↗

57. M.F. Zayed, R.A. Mahfoze, S.M. El-Kousy, E.A. Al-Ashkar, In-vitro antioxidant and antimicrobial activities of metal nanoparticles biosynthesized using optimized Pimpinella anisum extract. Colloids Surf. A Physicochem. Eng. Asp. 585, 124167 (2020)10.1016/j.colsurfa.2019.124167 ↗

58. R. Mariychuk, J. Fejer, J. Porubska, L.M. Grishchenko, V.V. Lisnyak, Green synthesis and characterization of gold triangular nanoprisms using extract of Juniperus communis L. Appl. Nanosci. 10(8), 2835–2841 (2020)10.1007/s13204-019-00990-x ↗

59. F. Fayazbakhsh, F. Hataminia, H.M. Eslam, M. Ajoudanian, S. Kharrazi, K. Sharifi, H. Ghanbari, Evaluating the antioxidant potential of resveratrol-gold nanoparticles in preventing oxidative stress in endothelium on a chip. Sci. Rep. 13(1), 21344 (2023)10.1038/s41598-023-47291-6 ↗

60. M. Hamelian, S. Hemmati, K. Varmira, H. Veisi, Green synthesis, antibacterial, antioxidant and cytotoxic effect of gold nanoparticles using Pistacia atlantica extract. J. Taiwan Inst. Chem. Eng. 93, 21–30 (2018)10.1016/j.jtice.2018.07.018 ↗

61. O.M. El-Borady, M.S. Ayat, M.A. Shabrawy, P. Millet, Green synthesis of gold nanoparticles using Parsley leaves extract and their applications as an alternative catalytic, antioxidant, anticancer, and antibacterial agents. Adv. Powder Technol. 31(10), 4390–4400 (2020)10.1016/j.apt.2020.09.017 ↗

62. V. Vinotha, A. Iswarya, R. Thaya, M. Govindarajan, N.S. Alharbi, S. Kadaikunnan, J.M. Khaled, M.N. Al-Anbr, B. Vaseeharan, Synthesis of ZnO nanoparticles using insulin-rich leaf extract: anti-diabetic, antibiofilm and anti-oxidant properties. J. Photochem. Photobiol. B, Biol. 197, 111541 (2019)10.1016/j.jphotobiol.2019.111541 ↗

63. T. Sarkar, K.K. Bharadwaj, M. Salauddin, S. Pati, R. Chakraborty, Phytochemical characterization, antioxidant, anti-inflammatory, anti-diabetic properties, molecular docking, pharmacokinetic profiling, and network pharmacology analysis of the major phytoconstituents of raw and differently dried Mangifera indica (Himsagar cultivar): an in vitro and in silico investigations. Appl. Biochem. Biotechnol. (2021). https://doi.org/10.1007/s12010-021-03669-810.1007/s12010-021-03669-8 ↗

64. V. Ajayi, T. Adebayo and A. Lateef, Novel multitasking gold nanoparticles biosynthesized by Cassia fistula: antifungal, anti-obesity, anti-diabetic, and anti-ulcer activities. (2023)10.21203/rs.3.rs-3590139/v1 ↗

65. Ł Niżnik, M. Noga, D. Kobylarz, A. Frydrych, A. Krośniak, L. Kapka-Skrzypczak, K. Jurowski, Gold nanoparticles (AuNPs)—toxicity, safety and green synthesis: a critical review. Int. J. Mol. Sci. 25(7), 4057 (2024)10.3390/ijms25074057 ↗

66. K.-T. Kim, L.-E. Rioux, S.L. Turgeon, Alpha-amylase and alpha-glucosidase inhibition is differentially modulated by fucoidan obtained from Fucus vesiculosus and Ascophyllum nodosum. Phytochemistry 98, 27–33 (2014)10.1016/j.phytochem.2013.12.003 ↗

67. I. Khan, S. Bawazeer, A. Rauf, M.N. Qureshi, N. Muhammad, Y.S. Al-Awthan, O. Bahattab, A. Maalik, K.R. Rengasamy, Synthesis, biological investigation and catalytic application using the alcoholic extract of Black Cumin (Bunium persicum) seeds-based silver nanoparticles. J. Nanostruct. Chem. (2022). https://doi.org/10.1007/s40097-021-00402-z10.1007/s40097-021-00402-z ↗

68. O. Afuye, A.A. Olasunkanmi, Green synthesis of MgO nanoparticles using Anona muricata leaf aqueous extract and its antidiabetic activity. International Journal of Women in Technical Education and Employment 3(2), 59–67 (2022)

69. V. Sekar, M.M. Al-Ansari, J. Narenkumar, L. Al-Humaid, P. Arunkumar, A. Santhanam, Synthesis of gold nanoparticles (AuNPs) with improved anti-diabetic, antioxidant and anti-microbial activity from Physalis minima. J. King Saud Univ. Sci. 34(6), 102197 (2022)10.1016/j.jksus.2022.102197 ↗

70. A. Loyola-Leyva, K. Hernández-Vidales, J. Ruiz-García, J.P. Loyola-Rodríguez, Characterization of green synthesized nanoparticles with anti-diabetic properties. A systematic review. Curr. Diabetes Rev. 21(7), E200524230102 (2025)10.2174/0115733998306451240425135229 ↗

71. N. Assad, M.B. Laila, M.N.U. Hassan, MFu.. Rehman, L. Ali, M. Mustaqeem, B. Ullah, M.N. Khan, M. Iqbal, S. Ercişli, Eco-friendly synthesis of gold nanoparticles using Equisetum diffusum D. Don. with broad-spectrum antibacterial, anticancer, antidiabetic, and antioxidant potentials. Sci. Rep. 15(1), 19246 (2025)10.1038/s41598-025-02450-9 ↗

72. G. Gawas, M. Ayyanar, N. Gurav, D. Hase, V. Murade, S. Nadaf, M.S. Khan, R. Chikhale, M. Kalaskar, S. Gurav, Process optimization for the bioinspired synthesis of gold nanoparticles using cordyceps militaris, its characterization, and assessment of enhanced therapeutic efficacy. Pharmaceuticals. 16(9), 1311 (2023)10.3390/ph16091311 ↗

73. M. Kiran, C.R. Kumar, U. Shwetha, H. Onkarappa, V. Betageri and M. Latha: Green synthesis and characterization of gold nanoparticles from Moringa oleifera leaves and assessment of antioxidant, antidiabetic and anticancer properties, (Elsevier, City, 2021), p. 100714.10.1016/j.cdc.2021.100714 ↗

74. F. Mahmoudi, F. Mahmoudi, K.H. Gollo, M.M. Amini, Novel gold nanoparticles: Green synthesis with eryngium thyrsoideum Boiss extract, characterization, and in vivo investigations on inflammatory gene expression and biochemical parameters in type 2 diabetic rats. Biol. Trace Elem. Res. 200(5), 2223–2232 (2022)10.1007/s12011-021-02819-7 ↗

75. Y. Guo, N. Jiang, L. Zhang, M. Yin, Green synthesis of gold nanoparticles from Fritillaria cirrhosa and its anti-diabetic activity on Streptozotocin induced rats. Arab. J. Chem. 13(4), 5096–5106 (2020)10.1016/j.arabjc.2020.02.009 ↗

76. S. Ayyoub, B. Al-Trad, A.A. Aljabali, W. Alshaer, M. Al Zoubi, S. Omari, D. Fayyad, M.M. Tambuwala, Biosynthesis of gold nanoparticles using leaf extract of Dittrichia viscosa and in vivo assessment of its anti-diabetic efficacy. Drug Deliv. Transl. Res. 12(12), 2993–2999 (2022)10.1007/s13346-022-01163-0 ↗

77. A.A. Omolaja, B. Pearce, S.I. Omoruyi, J.A. Badmus, E. Ismail, J. Marnewick, S. Botha, M. Benjeddou, O.E. Ekpo, A.A. Hussein, The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus. Surf. Interfaces 25, 101251 (2021)

78. S. Veeramani, A.P. Narayanan, K. Yuvaraj, R. Sivaramakrishnan, A. Pugazhendhi, I. Rishivarathan, S.P. Jose, R. Ilangovan, Nigella sativa flavonoids surface coated gold NPs (Au-NPs) enhancing antioxidant and anti-diabetic activity. Process Biochem. 114, 193–202 (2022)10.1016/j.procbio.2021.01.004 ↗