Nanozyme-enhanced mitophagy to improve the efficacy of mesenchymal stem cells in myocardial infarction therapy

1. Mechanisms of mitophagy in cellular homeostasis, physiology and pathology10.1038/s41556-018-0176-2 ↗

2. Cellular mitophagy: mechanism, roles in diseases and small molecule pharmacological regulation10.7150/thno.79876 ↗

3. Mitochondrial dynamics and mitophagy in cardiometabolic disease

4. Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy10.1016/j.redox.2021.102010 ↗

5. Predicting death after acute myocardial infarction10.1016/j.tcm.2017.07.011 ↗

6. AKI and long-term risk for cardiovascular events and mortality10.1681/ASN.2016010105 ↗

7. B.R. Chaitman, K.P. Alexander, D.D. Cyr, J.S. Berger, H.R. Reynolds, S. Bangalore, W.E. Boden, R.D. Lopes, M. Demkow, G. Piero Perna, R.K. Riezebos, E.O. McFalls, S. Banerjee, A. Bagai, G. Gosselin, S.M. O'Brien, F.W. Rockhold, D.D. Waters, K.A. Thygesen, G.W. Stone, H.D. White, D.J. Maron, J.S. Hochman, I.R. Group, Myocardial infarction in the ischemia trial: impact of different definitions on incidence, prognosis, and treatment comparisons, Circulation 143(8) (2021) 790–804. https://doi.org/10.1161/CIRCULATIONAHA.120.047987.10.1161/CIRCULATIONAHA.120.047987 ↗

8. Use of mesenchymal stem cells for therapy of cardiac disease10.1161/CIRCRESAHA.116.303614 ↗

9. Regenerative cardiovascular therapies: stem cells and beyond10.3390/ijms20061420 ↗

10. The pivotal roles of exosomes derived from endogenous immune cells and exogenous stem cells in myocardial repair after acute myocardial infarction10.7150/thno.53326 ↗

11. The vital roles of mesenchymal stem cells and the derived extracellular vesicles in promoting angiogenesis after acute myocardial infarction10.1089/scd.2021.0006 ↗

12. Inflammation in myocardial infarction: roles of mesenchymal stem cells and their secretome10.1038/s41420-022-01235-7 ↗

13. Combining stem cells in myocardial infarction: the road to superior repair?10.1002/med.21839 ↗

14. New strategies for improving stem cell therapy in ischemic heart disease10.1007/s10741-016-9576-1 ↗

15. Improving the engraftment and integration of cell transplantation for cardiac regeneration10.1093/cvr/cvz237 ↗

16. Beyond oxidative stress: an immunologist's guide to reactive oxygen species10.1038/nri3423 ↗

17. Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes10.1039/c3cs35486e ↗

18. Construction of a chiral artificial enzyme used for enantioselective catalysis in live cells10.1039/D0SC03082A ↗

19. Redox dyshomeostasis strategy for tumor therapy based on nanomaterials chemistry10.1039/D1SC06315D ↗

20. 2D vanadium carbide MXenzyme to alleviate ROS-mediated inflammatory and neurodegenerative diseases10.1038/s41467-021-22278-x ↗

21. A self-sustaining antioxidant strategy for effective treatment of myocardial infarction

22. Redox activation of ATM enhances GSNOR translation to sustain mitophagy and tolerance to oxidative stress10.15252/embr.202050500 ↗

23. Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling10.1161/01.CIR.0000062649.63838.C9 ↗

24. Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction10.1161/CIRCRESAHA.109.212589 ↗

25. Massive mechanical loss of microspheres with direct intramyocardial injection in the beating heart: implications for cellular cardiomyoplasty10.1016/j.jtcvs.2006.05.034 ↗

26. hESCs-derived early vascular cell spheroids for cardiac tissue vascular engineering and myocardial infarction treatment

27. Antioxidant nanozyme-engineered mesenchymal stem cells for in vivo MRI tracking and synergistic therapy of myocardial infarction

28. Route of delivery modulates the efficacy of mesenchymal stem cell therapy for myocardial infarction: a Meta-analysis of preclinical studies and clinical trials10.1161/CIRCRESAHA.116.309819 ↗

29. Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair10.1038/s41467-021-21682-7 ↗

30. Biosafety and biocompatibility assessment of Prussian blue nanoparticles in vitro and in vivo10.2217/nnm-2020-0191 ↗

31. Prussian blue: a nanozyme with versatile catalytic properties10.3390/ijms22115993 ↗

32. Prussian blue analogue nanoenzymes mitigate oxidative stress and boost bio-fermentation10.1039/C9NR04951G ↗

33. Prussian blue scavenger ameliorates hepatic ischemia-reperfusion injury by inhibiting inflammation and reducing oxidative stress

34. Hollow Prussian blue nanozymes drive neuroprotection against ischemic stroke via attenuating oxidative stress, counteracting inflammation, and suppressing cell apoptosis10.1021/acs.nanolett.8b04729 ↗

35. Catalytically synthesized Prussian blue nanoparticles defeating natural enzyme peroxidase10.1021/jacs.8b05223 ↗

36. Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia10.1016/j.biomaterials.2022.121690 ↗

37. RBC membrane camouflaged Prussian blue nanoparticles for gamabutolin loading and combined chemo/photothermal therapy of breast cancer10.1016/j.biomaterials.2019.119301 ↗

38. Progress in the preparation of Prussian blue-based nanomaterials for biomedical applications10.1039/D2TB02617A ↗

39. The inflammatory response in myocardial injury, repair, and remodelling10.1038/nrcardio.2014.28 ↗

40. Alternative strategy to optimize cerium oxide for enhanced X-ray-induced photodynamic therapy10.1021/acsnano.2c08047 ↗

41. Indocyanine green-modified hollow mesoporous Prussian blue nanoparticles loading doxorubicin for fluorescence-guided tri-modal combination therapy of cancer10.1039/C8NR10430A ↗

42. Hyaluronic acid modified hollow Prussian blue nanoparticles loading 10-hydroxycamptothecin for targeting thermochemotherapy of cancer10.7150/thno.13250 ↗

43. Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography10.1016/S0039-6257(00)00123-5 ↗

44. Indocyanine green-conjugated magnetic Prussian blue nanoparticles for synchronous photothermal/photodynamic tumor therapy

45. Thermosensitive hydrogel incorporating Prussian blue nanoparticles promotes diabetic wound healing via ROS scavenging and mitochondrial function restoration10.1021/acsami.1c24569 ↗

46. Engineering ROS-scavenging Prussian blue nanozymes for efficient atherosclerosis nanotherapy10.1039/D2TB02661A ↗

47. Two-photon nanoprobes based on bioorganic nanoarchitectonics with a photo-oxidation enhanced emission mechanism10.1038/s41467-023-40897-4 ↗

48. Key role of microtubule and its acetylation in a Zinc Oxide nanoparticle-mediated lysosome-autophagy system10.1002/smll.201901073 ↗

49. Leonurine protects bone mesenchymal stem cells from oxidative stress by activating mitophagy through PI3K/Akt/mTOR pathway10.3390/cells11111724 ↗

50. Mitochondrial autophagy: molecular mechanisms and implications for cardiovascular disease10.1038/s41419-022-04906-6 ↗

51. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy10.1038/nature14893 ↗

52. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria10.1073/pnas.1523926113 ↗

53. BNIP3 interacting with LC3 triggers excessive mitophagy in delayed neuronal death in stroke10.1111/cns.12325 ↗

54. Retention and functional effect of adipose-derived stromal cells administered in alginate hydrogel in a rat model of acute myocardial infarction