Modified implant with dual functions of antioxidant and extracellular matrix reconstruction for regulating MSCs senescence
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OpenAlex topics: Bone Tissue Engineering Materials · Facial Trauma and Fracture Management · Graphene and Nanomaterials Applications
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References (60)
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1. Anon · 2022
2. Cellular senescence in bone10.1016/j.bone.2019.01.015 ↗
3. Orthopedic implants and devices for bone fractures and defects: past, present and perspective10.1016/j.engreg.2020.05.003 ↗
4. Ti based biomaterials, the ultimate choice for orthopaedic implants – A review10.1016/j.pmatsci.2008.06.004 ↗
5. Bone and metal: an orthopaedic perspective on osseointegration of metals10.1016/j.actbio.2014.06.004 ↗
6. Systemic bone loss after fracture10.1007/s12018-018-9253-0 ↗
7. The elevated level of IL-1α in the bone marrow of aged mice leads to MSC senescence partly by down-regulating Bmi-110.1016/j.exger.2021.111313 ↗
8. DNA damage in aging, the stem cell perspective10.1007/s00439-019-02047-z ↗
9. DNA damage, DNA repair, Aging, and Neurodegeneration10.1101/cshperspect.a025130 ↗
10. Microenvironmental contributions to hematopoietic stem cell aging10.3324/haematol.2018.211334 ↗
11. Oxidative stress in stem cell aging10.1177/0963689717735407 ↗
12. Epigenetic control of stem cell potential during homeostasis, Aging, and Disease10.1016/j.stem.2015.05.009 ↗
13. Epigenetic regulation of bone marrow stem cell aging: revealing epigenetic signatures associated with hematopoietic and mesenchymal stem cell aging10.14336/AD.2017.1213 ↗
14. Study on the dynamic biological characteristics of human bone marrow mesenchymal stem cell senescence10.1155/2019/6789823 ↗
15. Wnt/β-catenin signaling induces the aging of mesenchymal stem cells through promoting the ROS production10.1007/s11010-012-1498-1 ↗
16. Nanocatalytic biofunctional MOF coating on titanium implants promotes osteoporotic bone regeneration through cooperative pro-osteoblastogenesis MSC reprogramming10.1021/acsnano.2c07200 ↗
17. Autophagy in bone homeostasis and the onset of osteoporosis10.1038/s41413-019-0058-7 ↗
18. Metformin: from mechanisms of action to therapies10.1016/j.cmet.2014.09.018 ↗
19. Metformin and inflammation: its potential beyond glucose-lowering effect10.2174/1871530315666150316124019 ↗
20. Metformin reduces endogenous reactive oxygen species and associated DNA damage10.1158/1940-6207.CAPR-11-0536 ↗
21. Cultured cell-derived extracellular matrices to enhance the osteogenic differentiation and angiogenic properties of human mesenchymal stem/stromal cells10.1002/term.2907 ↗
22. Ageing and rejuvenation of tissue stem cells and their niches10.1038/s41580-022-00510-w ↗
23. Fibroageing: an ageing pathological feature driven by dysregulated extracellular matrix-cell mechanobiology10.1016/j.arr.2021.101393 ↗
24. Surface mediated in situ differentiation of mesenchymal stem cells on gene-functionalized titanium films fabricated by layer-by-layer technique10.1016/j.biomaterials.2009.03.037 ↗
25. Genipin-crosslinked catechol-chitosan mucoadhesive hydrogels for buccal drug delivery10.1016/j.biomaterials.2014.10.024 ↗
26. Chitosan-catechol: a polymer with long-lasting mucoadhesive properties10.1016/j.biomaterials.2015.02.010 ↗
27. TiO2 nanotubes as drug nanoreservoirs for the regulation of mobility and differentiation of mesenchymal stem cells10.1016/j.actbio.2011.10.021 ↗
28. Cecropin B loaded TiO2 nanotubes coated with hyaluronidase sensitive multilayers for reducing bacterial adhesion10.1016/j.matdes.2015.12.126 ↗
29. Surface functionalization of TiO 2 nanotubes with bone morphogenetic protein 2 and its synergistic effect on the differentiation of mesenchymal stem cells10.1021/bm1014365 ↗
30. The molecular mechanism of mediation of adsorbed serum proteins to endothelial cells adhesion and growth on biomaterials10.1016/j.biomaterials.2013.04.028 ↗
31. Recent advance in surface modification for regulating cell adhesion and behaviors10.1515/ntrev-2020-0076 ↗
32. Surface characterization of TiO2 nanotube arrays produced on Ti6Al4V alloy by anodic oxidation10.1016/j.surfcoat.2021.127903 ↗
33. Mediation of biomaterial–cell interactions by adsorbed proteins: a review10.1089/ten.2005.11.1 ↗
34. Osteoblast adhesion on biomaterials10.1016/S0142-9612(99)00242-2 ↗
35. Drug-Releasing Tannic acid-mediated adhesive PEG hydrogel for porous titanium implants10.1021/acsomega.3c06966 ↗
36. TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA10.1038/s41556-024-01419-6 ↗
37. Manganese-induced alpha-synuclein overexpression aggravates mitochondrial damage by repressing PINK1/Parkin-mediated mitophagy10.1016/j.fct.2021.112213 ↗
38. Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS–AMPK–mTOR axis10.1038/s41419-019-1728-5 ↗
39. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer10.1016/j.smim.2014.01.001 ↗
40. Macrophage-derived interleukin-1beta promotes human breast cancer cell migration and lymphatic adhesion in vitro10.1007/s00262-017-2020-0 ↗
41. Feprazone mitigates IL-1β-induced cellular senescence in chondrocytes10.1021/acsomega.0c06066 ↗
42. Activation of interleukin-6/signal transducer and activator of transcription 3 by human papillomavirus early proteins 6 induces fibroblast senescence to promote cervical tumourigenesis through autocrine and paracrine pathways in tumour microenvironment10.1016/j.ejca.2013.07.140 ↗
43. Regulated cell death (RCD) in cancer: key pathways and targeted therapies10.1038/s41392-022-01110-y ↗
44. Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK /NF -κ B activation10.1111/acel.12075 ↗
45. Aging-associated lncRNAs are evolutionarily conserved and participate in NFκB signaling10.1038/s43587-021-00056-0 ↗
46. Mesenchymal stem cells repair bone marrow damage of aging rats and regulate autophagy and aging genes10.1002/cbf.3548 ↗
47. Mitochondrial dysfunction in aging10.1016/j.arr.2023.101955 ↗
48. Rejuvenating aged bone repair through multihierarchy reactive oxygen species-regulated hydrogel
49. A redox homeostasis modulatory hydrogel with glrx3 + extracellular vesicles attenuates disc degeneration by suppressing nucleus pulposus cell senescence10.1021/acsnano.3c01713 ↗
50. Mesenchymal stem cells. A potential source for skeletal repair10.1136/ard.61.suppl_2.ii29 ↗
51. Adipocyte accumulation in the bone marrow during obesity and aging impairs stem cell-based hematopoietic and bone regeneration10.1016/j.stem.2017.02.009 ↗
52. A smart fluorescence nanoprobe for the detection of cellular alkaline phosphatase activity and early osteogenic differentiation10.1016/j.nano.2016.01.010 ↗
53. Fabrication of strontium-incorporated protein supramolecular nanofilm on titanium substrates for promoting osteogenesis10.1016/j.msec.2020.110851 ↗
54. A dual-functional implant with an enzyme-responsive effect for bacterial infection therapy and tissue regeneration10.1039/C9BM01924C ↗
55. Aptamer/hydroxyapatite-functionalized titanium substrate promotes implant osseointegration via recruiting mesenchymal stem cells10.1021/acsami.2c10809 ↗
56. Cellular proliferation, self-assembly, and modulation of signaling pathways in silk fibroin gelatin-based 3D bioprinted constructs10.1021/acsabm.0c01252 ↗
57. Functions of the bone morphogenetic protein signaling pathway through non-coding RNAs10.1016/j.ncrna.2022.07.002 ↗
58. Bioactive fluorescent hybrid microparticles as a stand-alone osteogenic differentiation inducer
59. Attenuation of osteoarthritis progression via locoregional delivery of Klotho-expressing plasmid DNA and Tanshinon IIA through a stem cell-homing hydrogel10.1186/s12951-024-02608-z ↗
60. Mesenchymal stem/stromal cell senescence: hallmarks, Mechanisms, and Combating Strategies10.1093/stcltm/szac004 ↗